UID:
almafu_9961809024102883
Format:
1 online resource (XXXVIII, 736 p.)
ISBN:
9783111341996
Series Statement:
De Gruyter Series in Mathematics and Life Sciences , 9
Content:
This book aims to engage “Young Science – Talented & Ambitious” for a lasting collaboration to advance holistic mathematical modeling of “how the body works” in variant surroundings. The book sets road signs to mathematics in body’s vital, physical, and cognitive functions, as well as to factors of health impact in person’s environmental and social settings. It showcases selected current research in mathematical and biological theory, mathematical models at molecular, organism, and population levels as well as engineering, imaging, and data sciences methodologies, including bio-informatics and machine learning applications. For overarching theory, evaluation of surrogate structures with category theory, multi-scale whole-body dynamics by separation of functional organization from cellular material as well as mathematical axioms matching classic principles of philosophy in traditional Chinese medicine are introduced. Interested are systems-oriented researchers in all sciences related to human health who seek new profile-shaping challenges in transdisciplinary collaboration.
Note:
Frontmatter --
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Prologue I --
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Prologue II --
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Prologue III --
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Preface --
,
Overview --
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Contents --
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Part I: Theories --
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Part I-A: Overarching theory --
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Introduction --
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Universal axioms in classical Chinese philosophy --
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Category theory for structural characterization --
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Axiomatic bipolar dynamics and their control --
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Part I-B: Systems theories --
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Introduction --
,
Stochastic formalization of agent-oriented systems --
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Simplification of high-dimensional multitempo dynamic models --
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Ideas of symmetry as a biophysical basis of system biomedicine --
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Disorder of multiscale control --
,
Part II: Person’s life-sphere --
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Part II-A: Person’s biosphere --
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Introduction --
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Mutations as activators of biological evolutionary processes at population levels --
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Immunometabolism of T-cells in COVID-19 --
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Part II-A.2: Body’s vital functions --
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Introduction --
,
Structural modeling of vascular networks --
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Mathematical modeling of AI application for the diagnosis of blood flow disorders --
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Modeling of glucose and insulin regulation within the framework of a self-consistent model of the cardiovascular system --
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Hemodynamics in residual myocardial ischemia --
,
The quasi-one-dimensional model of the lymph flow in the human lymphatic system --
,
An integrate-and-fire mechanism for modeling rhythmicity in the neuroendocrine system --
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Kinetic network modeling of the neuroendocrine hypothalamic-pituitary-adrenal axis dynamics with particular attention on the role of alcohol as a digestif --
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Inflammation and immune response in atherosclerosis --
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Part II-A.3: Body’s motor functions --
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Introduction --
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A magnetic resonance spectroscopy approach to quantitatively measure GABA and phosphorus level changes in the primary motor cortex elicited by transcranial direct current stimulation --
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Part II-A.4: Body’s operational functions --
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Introduction --
,
The fermionic mind hypothesis–a category-theoretic verification of consciousness --
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Cross-task cognitive workload measurement based on the sample selection of the EEG data --
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Part II-B: Person’s eco-sphere exposures --
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Introduction --
,
The spread of SARS-CoV-2 in Russia and the evolution of the properties of the pathogen --
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Agent-based modeling of epidemic spread via kinetic Monte Carlo method --
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Control of SARS-nCoV outbreaks in China 2020 --
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Part II-B.2: Civilization --
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Introduction --
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Pesticide exposure: Toward holistic environmental modeling --
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Part II-C: Person’s sociosphere exposures --
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Introduction --
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Evolution of the health system in Shanghai, China, 2016–2020 --
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Part III: Technologies --
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Introduction --
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Design-process automation using functional process blocks --
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Slow/fast dynamic models with applications to engineering problems --
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Part III-B: Information sciences --
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Introduction --
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Numerical modeling of medical ultrasound using the grid-characteristic method --
,
The direct and the inverse magnetic encephalography problem --
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Part III-C: Data-analytic sciences --
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Introduction --
,
Assessing the bioequivalence of two different drugs with the same active ingredient --
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Estimation of adjusted relative risks in log-binomial regression using the Bekhit–Schöpe–Wagenpfeil algorithm --
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Part IV: Clinical medicine --
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Introduction --
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Finding optimal two-stage combined treatment protocols for a blood cancer model --
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Unraveling the mysteries: Mathematical perspectives on traditional Chinese medicine meridians --
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Epilogue --
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Index
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Issued also in print.
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In English.
Additional Edition:
ISBN 9783111342047
Additional Edition:
ISBN 9783111341972
Language:
English
DOI:
10.1515/9783111341996
URL:
https://doi.org/10.1515/9783111341996
URL:
https://www.degruyter.com/isbn/9783111341996
URL:
Volltext
(URL des Erstveröffentlichers)
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