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  • 1
    Article
    Article
    Language: English
    In: Science (New York, N.Y.), 11 August 2017, Vol.357(6351), pp.618
    Description: I was halfway through my Ph.D. coursework and struggling to define my nebulous research topic, with deadlines hurtling toward me and the MATLAB error beep propagating through my skull like a cluster bomb, when it all became too much. Smashing the keyboard in frustration and ripping incomprehensible
    Keywords: Sciences (General) ; Biology;
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 2
    In: Nature, 2011, Vol.471(7338), p.267
    Description: Abstract not available.
    Keywords: Carbon ; Forests ; Solid State Milieux (General) (So) ; Design Principles, Theory, and Analysis (Mt) ; General and Nonclassified (MD) ; General and Nonclassified (Ep) ; General and Nonclassified (Ed) ; General and Nonclassified (EC) ; Electronics and Communications Milieux (General) (Ea) ; Computing Milieux (General) (Ci) ; Surveying, Theory, and Analysis (CE) ; (An);
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 3
    Language: English
    In: Nursing Standard, June 13, 2012, Vol.26(41), p.26(2)
    Keywords: International Cooperation -- Reports ; Nurses -- Reports
    ISSN: 0029-6570
    E-ISSN: 20479018
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  • 4
    Language: English
    In: Nursing Standard, May 23, 2012, Vol.26(38), p.64(1)
    Keywords: College Students -- Education ; Educational Programs -- Analysis
    ISSN: 0029-6570
    E-ISSN: 20479018
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  • 5
    In: Nature, 2010, Vol.464(7287), p.355
    Description: Here in France, the Appellation d'Origine Contrôlée (AOC) system [which certifies a food's geographical origin] is right and there is a measurable difference between locations - a real terroir. After decades of my promoting it, chefs have recently taken up using rotary evaporators - a device available...
    Keywords: Molecules ; Chefs ; Taste;
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 6
    In: International Journal of Obesity, 2010, Vol.35(5), p.748
    Description: The primary purpose of our study was to determine the role of uric acid in fructose-mediated metabolic effects, and as such our study compared the effects of fructose supplementation with or without allopurinol (a xanthine oxidase inhibitor). The reason we used high doses of fructose was to ensure the robust metabolic effects that would better allow distinction of the role of uric acid. Although the study was single blinded, the laboratory tests were performed by technicians blinded to the two groups and the blood pressure readings were made by an automated 24 h ambulatory blood pressure equipment. Hence, all results consisted of ‘hard’ data. An important finding in our study was the observation that fructose can raise blood pressure and that this was uric acid dependent. These studies are consistent with epidemiological studies1, 2 and a recent clinical trial.3We agree that inclusion of a glucose control group would have been beneficial. However, a carefully performed clinical trial by Stanhope et al.4 has already documented that fructose, but not glucose, induces features of metabolic syndrome in humans. Experimental studies have also documented that fructose is distinct from glucose in its ability to induce metabolic syndrome and that this is independent of energy intake.5, 6 These data are consistent with a recent meta-analysis that found that high-fructose corn syrup-containing beverages increase the risk for metabolic syndrome and diabetes.7Our finding that we induced metabolic syndrome in 25% of adults within 2 weeks is of great concern. Although we agree that the rapidity of this induction is likely because of the large doses of fructose used in this study, it raises the specter that lower doses of fructose may cause similar effects over a longer period of time and would be consistent with the observation that obesity and metabolic syndrome develop over years in humans. For example, although it takes only 2 months to induce insulin resistance with 60% fructose in rats, studies show that a 15% fructose diet can induce insulin resistance in 15 months.8In conclusion, we believe our study makes an important contribution on the role of excessive fructose in inducing metabolic syndrome and on the role of fructose-induced hyperuricemia in the blood pressure response. Although the doses of fructose used in the study were large, we must remember that some groups, such as young adults and children, are ingesting as much as 20–30% of their diet as added sugars. Other groups, such as African Americans and Hispanic Americans, are ingesting disproportionately higher amounts of fructose-containing sugars. When one further notes that the coexistent glucose can enhance fructose absorption in the intestine, our study gains additional clinical relevance. Hence, we strongly recommend public health measures to reduce the intake of fructose-containing sugars in the population; we believe this will have a major benefit to prevent obesity, diabetes and hypertension, with overall benefits to cardiovascular health.Dr Johnson has a lay book, The Sugar Fix (Rodale, Simon and Schuster) and is also listed as an inventor on several patent applications related to blocking the effects of fructose to induce obesity and metabolic syndrome. All other authors declare no conflict of interest.
    Keywords: Medicine ; Diet & Clinical Nutrition ; Recreation & Sports;
    ISSN: 0307-0565
    E-ISSN: 14765497
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  • 7
    Article
    Article
    In: Nature, 2013, Vol.498(7452), p.36
    ISSN: 0028-0836
    E-ISSN: 14764687
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  • 8
    Language: English
    In: Nature, April 1, 2010, Vol.464(7289), p.691(2)
    Keywords: Animal Physiology -- Research ; Body Mass Index -- Physiological Aspects ; Body Mass Index -- Research ; Energy Metabolism -- Physiological Aspects ; Energy Metabolism -- Research
    ISSN: 0028-0836
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  • 9
    In: Journal of Advanced Nursing, February 2014, Vol.70(2), pp.282-294
    Description: Byline: Lacie White Keywords: concept analysis; evolutionary method; holistic; mindfulness; nursing; presence; self-care Abstract Aim To report an analysis of the concept of mindfulness. Background Mindfulness is an emerging concept in health care that has significant implications for a variety of clinical populations. Nursing uses this concept in limited ways, and subsequently requires conceptual clarity to further identify its significance, use and applications in nursing. Design Mindfulness was explored using Rodgers evolutionary method of concept analysis. Data Sources For this analysis, a sample of 59 English theoretical and research-based articles from the Cumulative Index to Nursing and Allied Health Literature database were obtained. The search was conducted between all-inclusive years of the database, 1981-2012. Review Methods Data were analysed with particular focus on the attributes, antecedents, consequences, references and related terms that arose in relation to mindfulness in the nursing literature. Results The analysis found five intricately connected attributes: mindfulness is a transformative process where one develops an increasing ability to 'experience being present', with 'acceptance', 'attention' and 'awareness'. Antecedents, attributes and consequences appeared to inform and strengthen one another over time. Mindfulness is a significant concept for the discipline of nursing with practical applications for nurse well-being, the development and sustainability of therapeutic nursing qualities and holistic health promotion. Conclusion It is imperative that nurse well-being and self-care become a more prominent focus in nursing research and education. Further development of the concept of mindfulness could support this focus, particularly through rigorous qualitative methodologies.
    Keywords: Concept Analysis ; Evolutionary Method ; Holistic ; Mindfulness ; Nursing ; Presence ; Self‐Care
    ISSN: 0309-2402
    E-ISSN: 1365-2648
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  • 10
    Language: English
    In: European Journal of Operational Research, 16 March 2016, Vol.249(3), pp.827-841
    Description: Stimulated by the growing interest in behavioural issues in the management sciences, research scholars have begun to address the implications of behavioural insights for Operational Research (OR). This current work reviews some foundational debates on the nature of OR to serve as a theoretical backdrop to orient a discussion on a behavioural perspective and OR. The paper addresses a specific research need by outlining that there is a distinct and complementary contribution of a behavioural perspective to OR. However, there is a need to build a theoretical base in which the insights from classical behavioural research is just one of a number of convergent building blocks that together point towards a compelling basis for behavioural OR. In particular, the focus of the paper is a framework that highlights the collective nature of OR practice and provides a distinct and interesting line of enquiry for future research.
    Keywords: Behavioural OR ; Process of OR ; Philosophy of OR ; Collective Behaviour ; Engineering ; Business ; Computer Science
    ISSN: 0377-2217
    E-ISSN: 1872-6860
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