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  • 1
  • 2
    Language: English
    In: Cancer Research, 07/15/2016, Vol.76(14 Supplement), pp.3259-3259
    Description: Angiopoeitin-2 (Ang2) is released from endothelial cells only in response to stimulus (e.g. wound healing, tumor growth) and facilitates blood vessel sprouting and inhibits pericyte-endothelial cell interaction via Tie2 signaling. Combination of an anti-Ang2 antibody and aflibercept,...
    Keywords: Cell Survival ; Vascular Endothelial Growth Factor ; Ovarian Cancer ; Retina ; Immunotherapy ; Animal Models ; Angiogenesis ; Pericytes ; Wound Healing ; Tumors ; Clinical Trials ; Metastases ; Endothelial Cells ; Antibodies ; Blood Vessels ; Immunoglobulin G ; Cell Interactions ; Xenografts ; Products;
    ISSN: 0008-5472
    E-ISSN: 1538-7445
    Source: CrossRef
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  • 3
    In: 南大商学评论, 2016, Vol.13(03), pp.59-72
    Description: "需求引致创新"是需求与创新关系中具有代表性的观点,国内外众多学者从市场规模、市场结构、市场需求三个方面证明了市场需求对企业创新具有非线性的正向作用。在我国进入中等收入水平、市场化改革不断深入、国际市场需求疲软的经济环境下,市场规模、市场结构、市场需求发生了动态改变。在此背景下,本文从这三个角度梳理了"需求引致创新"方面的文献,进一步指出现有研究的特点和不足之处,并从动态性角度给出后续研究的方向。
    Description: " Demand-induced innovation " is a representative point of view on the relationship between demand and innovation. Many scholars at home and abroad have proved that market demand has a positive nonlinear effect on enterprise innovation from three aspects, market size, market structure and market demand. In China, the market size, market structure and market demand have changed dynamically under the economic environment of middle income level, market-oriented reform and weak international market demand. In this context, the paper combs the literatures of "demand-induced innovation" from these three perspectives, further points out the characteristics and shortcomings of the existing researches, and gives the direction of the follow-up research from the dynamic point of view.
    Keywords: 市场规模 ; 市场结构 ; 市场需求 ; 企业创新 ; Market Size Market Structure Market Demand Enterprise Innovation
    Source: 维普数据 (Chongqing VIP Information Co.)
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  • 4
    In: 测绘通报 - Bulletin of Surveying and Mapping, 2012, Issue 01, pp.3-6
    Description: 采用静态与动态测量相结合的模式,可以很方便地获得基准站及流动站相对于平均观测历元时刻的ITRF框架坐标,与常规GPS RTK测量相比,该方法效率高,且获得的结果具有明确的基准定义。利用3个IGS跟踪站的数据,分析不同框架及历元下对应点的大地经纬度及大地高的差异情况,并分析其变化对GPS高程转换的影响。结果表明,不同框架及历元结果对GPS RTK高程转换的影响基本可忽略,该方法具有较好的应用价值。
    Keywords: Gpsrtk ; 静态和动态测量 ; 坐标框架 ; 历元 ; Gps高程转换
    ISSN: 0494-0911
    Source: 维普数据 (Chongqing VIP Information Co.)
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  • 5
    Language: English
    In: Electrochimica Acta, 01 May 2015, Vol.163, pp.93-101
    Description: A new type of hierarchical urchin-like Mn Co C O (HU-Mn Co C O ) is fabricated using a template-free chemical co-precipitation method. The morphology of this system is highly influenced by the Mn/Co ratio. The obtained urchin-like microspheres are composed of end-connected nanorods and accompanied by structural voids. When tested in lithium-ion batteries, HU-Mn Co C O delivers a high reversible discharge capacity of 924 mAh g at 500 mA g in the 2nd cycle, with 83% capacity retention over 300 cycles. Rate capability testing shows that HU-Mn Co C O can deliver discharge capacities of 734 mAh g at 1 A g and 414 mAh g at 5 A g , respectively. Although the transition-metal content and conductivity of HU-Mn Co C O are much lower than that of MnCo O , the material still exhibits a high specific capacity, good capacity retention, and excellent rate capability, suggesting that HU-Mn Co C O is a promising anode material for future lithium-ion batteries (LIBs). In addition, a gradual electrochemical activation process is observed to occur in the first several cycles, relating to the gradual generation of SEI layers on the electrode surface. It is found that the SEI layers on the surface of oxalate materials are predominantly composed of lithium alkyl carbonates from the reductive decomposition of electrolyte and the catalytic products of Li C O . We speculate that the formed SEI layers with high lithium ion conductivity play an important role in achieving the observed high specific capacities and excellent rate capabilities of oxalates.
    Keywords: Lithium Ion Battery ; Anode Material ; Cobalt-Manganese Oxalates ; Urchin-Like ; Sei Layer ; Engineering ; Chemistry
    ISSN: 0013-4686
    E-ISSN: 1873-3859
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  • 6
    Language: English
    In: Electrochimica Acta, May 1, 2015, Vol.163, p.93(9)
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.electacta.2015.02.134 Byline: Xuehang Wu, Jianghuai Guo, Matthew J. McDonald, Shiguang Li, Binbin Xu, Yong Yang Abstract: Display Omitted Author Affiliation: (a) State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China (b) School of Energy Research, Xiamen University, Xiamen 361005, China Article History: Received 18 December 2014; Revised 14 February 2015; Accepted 16 February 2015
    Keywords: Batteries – Chemical Properties ; Batteries – Electric Properties
    ISSN: 0013-4686
    Source: Cengage Learning, Inc.
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  • 7
    Language: Chinese
    In: China Cucurbits and Vegetables, 2010, Vol.(1), pp.1-3
    Description: 将12个线椒品种自交系分成2组,按NC-Ⅱ设计配制成36个杂交组合,估算 36个组合的品质、产量、熟性等10个性状的主成分值。结果表明,数量分类结果基本反映了线椒品种间的遗传差异,符合实际情况;当主成分特征值累计贡献率大于75% 时,主成分值即基本反映原来性状的遗传特征。
    Description: Twelve inbred long chili pepper lines were divided into two groups and 36 hybrids were made by NC-II. Principal components of 10 traits including quality,yield and maturity were estimated using the 36 hybrid long chili pepper. The results showed that the quantitative classification basically revealed the genetic differences among the varieties. When principal components explain more than 75% of variation,the principal components represent the genetic characteristics of the trait. ; Resume(Zh,En) ; 9 ref.
    Keywords: Pepper ; Quantitative Trait Loci ; Species ; Poivre ; Locus Des Caracteres Quantitatifs ; Espece ; Pimienta ; Loci De Rasgos Cuantitativos ; Especies
    ISSN: 1673-2871
    Source: AGRIS (Food and Agriculture Organization of the United Nations)
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  • 8
    Language: English
    In: The Journal of cell biology, 03 December 2007, Vol.179(5), pp.935-50
    Description: Ligand-induced endocytosis and lysosomal degradation of cognate receptors regulate the extent of cell signaling. Along with linear endocytic motifs that recruit the adaptin protein complex 2 (AP2)-clathrin molecules, monoubiquitination of receptors has emerged as a major endocytic signal. By investigating ubiquitin-dependent lysosomal degradation of the interferon (IFN)-alpha/beta receptor 1 (IFNAR1) subunit of the type I IFN receptor, we reveal that IFNAR1 is polyubiquitinated via both Lys48- and Lys63-linked chains. The SCF(betaTrcp) (Skp1-Cullin1-F-box complex) E3 ubiquitin ligase that mediates IFNAR1 ubiquitination and degradation in cells can conjugate both types of chains in vitro. Although either polyubiquitin linkage suffices for postinternalization sorting, both types of chains are necessary but not sufficient for robust IFNAR1 turnover and internalization. These processes also depend on the proximity of ubiquitin-acceptor lysines to a linear endocytic motif and on its integrity. Furthermore, ubiquitination of IFNAR1 promotes its interaction with the AP2 adaptin complex that is required for the robust internalization of IFNAR1, implicating cooperation between site-specific ubiquitination and the linear endocytic motif in regulating this process.
    Keywords: Endocytosis ; Ubiquitination ; Receptor, Interferon Alpha-Beta -- Chemistry
    ISSN: 00219525
    E-ISSN: 1540-8140
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  • 9
    In: 包装工程 - Packaging Engineering, 2014, Vol.35(07), pp.76-80
    Description: 目的研究八宝粥产品罐装包装凹陷变形的原因及解决方法。方法首先采用网络问卷的方式对216位消费者进行八宝粥产品包装消费者调查。再通过走访4家大型超市对7种品牌罐装包装八宝粥进行抽样调查,最后选取D牌八宝粥作为调查对象,进行从生产到销售上架的跟踪调查。结果货架上的八宝粥罐装包装凹陷现象较为严重,包装凹陷在一定程度上影响了消费者对八宝粥产品的认知及购买。八宝粥产品罐身凹陷变形出现在生产到销售各个环节.并且随着运输环节的增加,凹陷变形率也增加。结论八宝粥产品罐身凹陷变形主要出现在生产灌装封盖、杀菌冷却环节以及运输装卸环节.其改进可通过对各环节的综合管理得以实现。
    Description: Objective To study the causes and solutions of eight-ingredient porridge product canned packaging deformation. Methods First, an internet-based questionnaire was used to quiz 216 consumers about eight-ingredient porridge packaging. Second, a sampling investigation was conducted for seven brands of canned eight-ingredient porridge packaging by visiting four large supermarkets. Lastly, follow-up research of D brand eight-ingredient porridge was performed from production to sales. Results Dent problem in eight-ingredient porridge canned packaging was serious, which affected the consumers" perception and purchase of eight-ingredient porridge. Dents in canned packages of eight-ingredient porridge occurred in every link of produc- tion and sales, which increased with the increase of transport links. ConcLusion The eight-ingredient porridge canned packa- ging deformation mainly appeared in the filling, capping, sterilization, cooling process and handling procedure. The situation might be improved by integrated management of each link.
    Keywords: 八宝粥 ; 罐装包装 ; 马口铁三片罐 ; 凹陷 ; Eight-Ingredient Porridge; Canned Package; Tinplate Three-Piece Can; Dent
    ISSN: 1001-3563
    Source: 维普数据 (Chongqing VIP Information Co.)
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  • 10
    Language: English
    Description: China's Economic Issues is a series of in-depth studies of nine current macroeonomic issues in contemporary China. Featuring the work of leading Chinese experts and economists, each of these nine volumes focuses on a specific topic or sector of vital importance to the pace of China's economic reform....
    Keywords: Economics
    ISBN: 9781623200398
    ISBN: 1623200393
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