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  • Monograph/Item  (8)
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  • 1
    UID:
    (DE-627)167800541X
    Format: 1 Online-Ressource (53 Seiten, 2,56 MB) , Illustrationen, Diagramme
    Note: Förderkennzeichen BMBF 03ZZ0903H. - Verbund-Nummer 01160600 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Additional Edition: Erscheint auch als Druck-Ausgabe Basisvorhaben 2 "Grundlagenentwicklungen für Technologie-, Biomaterial- und Wirkstoffinnovationen" - Teilvorhaben H Jena : [INNOVENT e.V.], 2019
    Language: German
    Keywords: Implantat ; Implantatwerkstoff ; Beschichten ; Biokompatibilität ; Biopolymere ; Kontrollierte Wirkstofffreisetzung ; Funktionsgel ; Elektrospinnen ; Forschungsbericht
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  • 2
    UID:
    (DE-627)1657014185
    Format: Online-Ressource (XV, 830 p. 297 illus., 194 illus. in color, online resource)
    ISBN: 9783319680255
    Series Statement: SpringerLink
    Content: This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. The book then reviews general types of biomaterials - polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications - before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization - chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity - an d reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a broader selection of materials and implantable solutions. This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union
    Content: Chapter 1. Short History of Biomaterials Used in Hip Arthroplasty and their Modern Evolution -- Part 1: Material Classes -- Chapter 2. Progress Beyond the State-of-the-art in the Field of Metallic Materials for Bioimplant Applications -- Chapter 4. Polymeric Biomaterials in Clinical Practice -- Chapter 5. Polymeric Biomaterials Based on Polylactide, Chitosan and Hydrogels in Medicine -- Chapter 6. Polyethylene Based Polymer for Joint Replacement -- Chapter 7. Ceramics for Hip Joint Replacement -- Chapter 8. Metallic Biomaterials -- Chapter 9. Biodegradable Metals as Biomaterials for Clinical Practice: Iron-based Materials -- Chapter 10. Porous Metals in Orthopaedics -- Chapter 11. Properties and Behavior of Shape Memory Alloys in the Scope of Biomedical and Engineering Applications -- Chapter 12. Bioactive Biomaterials: Potential for Application in Bone Regenerative Medicine -- Chapter 13. Bioactive Coatings -- Chapter 14. Nanometals in Cancer Diagnosis and Therapy -- Part 2: Biomaterial Properties and Characterization -- Chapter 15. Chemical Bulk Properties of Biomaterials -- Chapter 16. Assessment of Metallic Alloys Biocompatibility -- Chapter 17. Determining the Biological Properties of Biomaterials In Vivo -- Chapter 18. Genotoxicity and Mutagenicity Testing of Biomaterials -- Chapter 19. Histopathological Analysis of Bone Tissue Reaction on Implanted Biomaterials -- Chapter 20. Imaging in Clinical and Preclinical Practice -- Chapter 21. Selected Instrumental Methods for Physicochemical and Spectroscopic Characterization of Different Biomaterials -- Chapter 22. An Overview of In Vitro Mechanical and Structural Characterization of Hip Prosthesis Components -- Chapter 23. Characterization of Mechanical Properties of Metal Biomaterials -- Chapter 24. Manufacturability of Biomaterials -- Chapter 25. Computer Modeling of Stent Deployment in the Coronary Artery Coupled with Plaque Progression -- Part 3: Clinical Applications -- Chapter 26. Biomaterials in Dentistry - Implantology and Guided Bone Regeneration -- Chapter 27. Knee Arthroplasties -- Chapter 28. Total Endoprothesis of Hip Joint: Characteristics and Application in Patients in the Central Region of Serbia
    Additional Edition: 9783319680248
    Additional Edition: Druckausg. 978-3-319-68024-8
    Additional Edition: Printed edition 9783319680248
    Language: English
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 3
    UID:
    (DE-627)166580971X
    Format: 1 Online-Ressource (74 Seiten, 6,01 MB) , Illustrationen, Diagramme
    Note: Förderkennzeichen BMBF 03WKCB01F. - Verbund-Nummer 01089225 , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Additional Edition: Erscheint auch als Druck-Ausgabe Berg, Albrecht Innovativer, regionaler Wachstumskern - BASIS - BioAnalytics and surfaces for integrations in systems Jena : INNOVENT e.V. Technologieentwicklung Jena, 2018
    Language: German
    Keywords: Funktionsgel ; Biopolymere ; Lactone ; RGD-Sequenz ; Vernetzung ; Funktionalisierung ; Sol-Gel-Verfahren ; Biokompatibilität ; Sensor ; Implantat ; Forschungsbericht
    URL: Volltext  (kostenfrei)
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  • 4
    UID:
    (DE-627)1002850061
    Format: 1 Online-Ressource (823 pages)
    ISBN: 9783319680255
    Content: "Preface" -- "Contents" -- "About the Editors" -- "1 Short History of Biomaterials Used in Hip Arthroplasty and Their Modern Evolution" -- "Abstract" -- "1 Introduction" -- "1.1 Brief Digression of Hip Anatomy" -- "1.2 Overview of Problems Leading to Hip Surgery" -- "2 History of Biomaterials Used in THA" -- "2.1 The Advance in Hip Replacement Prosthesis" -- "3 Biomaterials Used for Contemporary Types of THA" -- "4 Development of Modern Biomaterials Used in THA" -- "References" -- "Material Classes" -- "2 Progress Beyond the State-of-the-Art in the Field of Metallic Materials for Bioimplant Applications" -- "Abstract" -- "1 Introduction" -- "2 Fundamentals of BMGs" -- "3 Permanent Metallic Materials. Recent Advances on Ti-Based BMGs" -- "4 Biodegradable Metallic Materials. Recent Advances on Mg-Based BMGs" -- "5 Surface Engineering of Ti-Based Alloys" -- "6 Nanostructured Coatings by Hydrothermal Treatment on Biomedical Ti-Alloys" -- "7 Hydrothermally-Grown Coatings Enhance the Mechanical Properties and Corrosion Resistance" -- "8 Conclusions" -- "Acknowledgements" -- "References" -- "3 Review of Existing BiomaterialsâMethod of Material Selection for Specific Applications in Orthopedics" -- "Abstract" -- "1 Introduction" -- "2 Materials in Orthopedics" -- "2.1 Metal Materials" -- "2.1.1 Stainless Steel" -- "2.1.2 Cobalt Superalloys" -- "2.1.3 Titanium and Its Alloys" -- "2.2 Polymers" -- "2.3 Ceramics" -- "2.4 Composite Materials" -- "2.4.1 Practical Examples of Commercially Applied Composite Materials" -- "3 Advanced Material Structures" -- "3.1 Porous MetalsâMetal Foams" -- "3.2 Biodegradable Materials" -- "3.2.1 Biodegradable Polymers" -- "3.2.2 Biodegradable Metals" -- "3.3 Scaffolds" -- "3.4 Smart Biomaterials" -- "4 Case Study of Material Selection for the Femoral Component of an Artificial Hip Prosthesis
    Content: "4.1 Analysis of the Material Requirements in Case of a Hip Prosthesis" -- "Acknowledgements" -- "References" -- "4 Polymeric Biomaterials in Clinical Practice" -- "Abstract" -- "1 Polymeric BiomaterialsâBasis of Structure" -- "1.1 Mechanical Properties" -- "1.2 Degradation" -- "2 Applications of Polymers" -- "2.1 Polymers in Drug Delivery" -- "3 Summary" -- "References" -- "5 Polymeric Biomaterials Based on Polylactide, Chitosan and Hydrogels in Medicine" -- "Abstract" -- "1 Polymeric Biomaterials" -- "2 Introduction" -- "3 Poly(Lactic Acid)" -- "3.1 Properties of PLA" -- "3.2 Copolymers, Blends and Composites of PLA" -- "3.3 Application" -- "3.4 PLAâChallenges" -- "4 Chitosan" -- "4.1 Properties of Chitosan" -- "4.2 Application" -- "5 Hydrogels" -- "5.1 Natural Hydrogels (Biological Hydrogels)" -- "5.2 Synthetic Hydrogels" -- "5.3 Biohybrid Hydrogels" -- "5.4 Biomedical Applications of Hydrogels" -- "6 Future Perspectives" -- "References" -- "6 Polyethylene Based Polymer for Joint Replacement" -- "Abstract" -- "1 Introduction" -- "2 Improvements of Polyethylene for Joint Replacement" -- "2.1 Cross-linked Polyethylene" -- "2.2 Composite Polyethylenes" -- "3 Aging of Polyethylene" -- "4 Wear Tests on Polyethylene" -- "4.1 Polyethylene and Hip Wear Simulation" -- "4.2 Polyethylene and Knee Wear Simulation" -- "5 Molecular Characterization of PE" -- "6 Future Directions" -- "References" -- "7 Ceramics for Hip Joint Replacement" -- "Abstract" -- "1 Introduction" -- "2 Alumina for Hip Prostheses" -- "2.1 1st Generation of Alumina" -- "2.2 2nd Generation of Alumina" -- "2.3 3rd Generation of Alumina" -- "3 Zirconia Used as Medical Device" -- "3.1 Zirconia Toughened Alumina" -- "4 Wear Tests on Ceramic Components" -- "5 Molecular Characterization of Ceramic Materials" -- "6 Conclusions" -- "Acknowledgements" -- "References" -- "8 Metallic Biomaterials
    Content: "Abstract" -- "1 Introduction" -- "2 Basic Properties of the Metal Materials Used in Medicine" -- "2.1 Biocompatibility" -- "2.2 Corrosion Resistance" -- "2.3 Mechanical Properties" -- "2.4 Wear" -- "3 Metal Materials in Current Biomedical Applications" -- "3.1 Stainless Steel" -- "3.2 Titanium Alloys" -- "3.3 Cobalt-Based Alloys" -- "3.4 NiâTi Shape Memory Alloys" -- "3.5 Mg Alloys" -- "4 Summary and Looking to the Future" -- "References" -- "9 Biodegradable Metals as Biomaterials for Clinical Practice: Iron-Based Materials" -- "Abstract" -- "1 Introduction" -- "1.1 Application Areas of Degradable Implants" -- "1.2 Basic Properties" -- "1.3 Production Technologies" -- "1.4 Biodegradable Metal Materials" -- "2 Iron and Iron-Based Materials for Biodegradable Implants" -- "2.1 Iron Properties" -- "2.2 Iron Biochemistry" -- "2.3 Development of Biodegradable Medical Implants Made of Iron Based Materials" -- "2.3.1 Alloying Elements" -- "2.3.2 Composites" -- "2.3.3 Porosity" -- "2.3.4 Production Technologies" -- "2.3.5 Biocompatibility Properties" -- "2.3.6 Magnetic Properties" -- "2.3.7 Research DirectionâMaterial Degradation" -- "2.3.8 Modeling and Simulation" -- "3 Economic Impact of Biodegradable Metallic Implants" -- "4 Conclusions" -- "Acknowledgements" -- "References" -- "10 Porous Metals in Orthopedics" -- "Abstract" -- "1 Introduction" -- "2 Production" -- "3 Mechanical Properties" -- "4 Medical Device Testing for Porous Metals" -- "5 Materials" -- "6 Applications and Conclusions" -- "Acknowledgements" -- "References" -- "11 Properties and Behavior of Shape Memory Alloys in the Scope of Biomedical and Engineering Applications" -- "Abstract" -- "1 Introduction" -- "2 Shape Memory Alloy Properties: Experimental Investigation and Modeling" -- "2.1 SMA Constitutive Modeling Approaches" -- "2.2 Loading Rate Influence on SMA Behavior
    Content: "3 Applications of SMA" -- "3.1 Medical Application" -- "3.1.1 Orthodontic Application" -- "3.1.2 Orthopedic Application" -- "3.1.3 Cardiovascular Application" -- "3.1.4 Other Medical Applications" -- "3.2 Other Technical Applications" -- "4 Conclusions" -- "Acknowledgements" -- "References" -- "12 Bioactive Biomaterials: Potential for Application in Bone Regenerative Medicine" -- "Abstract" -- "1 Introduction to Bioactive Biomaterials in Medicine" -- "1.1 Implant-Tissue Interactions" -- "2 Classification of Biomaterials in Medicine" -- "2.1 Bioinert Biomaterials" -- "2.2 Bioactive Biomaterials" -- "3 Bioactive Biomaterials in Bone Regenerative Medicine" -- "3.1 Natural Bone Substitutes" -- "3.2 Synthetic Bone Substitutes" -- "3.2.1 Ceramics" -- "3.2.2 Metals" -- "3.2.3 Polymers" -- "3.2.4 Hydrogels" -- "3.2.5 Composites" -- "3.3 Nanomaterials" -- "4 Bioactive Biomaterials in Dentistry" -- "5 Bioactive Biomaterials in Drug Delivery Systems" -- "6 Future Directions and Perspectives" -- "Acknowledgements" -- "References" -- "13 Bioactive Coatings" -- "Abstract" -- "1 Introduction" -- "2 Processing/Characterisation/Biocompatibility and Bioactivity Properties of Bioactive Coatings" -- "2.1 Hydroxyapatite Coatings" -- "2.2 Bioglass Coatings" -- "2.3 Polymer-Based Bioactive and Degradable Coatings" -- "2.3.1 Natural Polymer Derived Coatings" -- "2.3.2 Bioactive and Degradable Coatings Based on Synthetic Polymers" -- "2.4 Bioactive Composite Coatings" -- "2.5 Antimicrobial Coatings" -- "3 Future Trends" -- "Acknowledgements" -- "References" -- "14 Nanometals in Cancer Diagnosis and Therapy" -- "Abstract" -- "1 Introduction" -- "2 Gold Nanomaterials" -- "3 Silver Nanomaterials (AgNMs)" -- "4 Magnetic Nanoparticles (MagNPs)" -- "5 Nanomaterials Characterization" -- "6 Nanometals in Cancer Imaging" -- "7 Nanometals in Drug Delivery
    Content: "8 Nanometals in Gene Therapy" -- "9 Metalnanomaterials in Photothermal Therapy" -- "10 Conclusions and Future Perspectives" -- "Acknowledgements" -- "References" -- "Biomaterial Properties and Characterization" -- "15 Chemical Bulk Properties of Biomaterials" -- "Abstract" -- "1 Introduction" -- "2 The Role of Water in the Interaction Between Biomaterials and the Living Matter" -- "3 Chemical Properties of Different Classes of Biomaterials" -- "3.1 Metals and Alloys" -- "3.2 Ceramics and Bioactive Glasses" -- "3.3 Polymers" -- "4 Concluding Remarks" -- "References" -- "16 Assessment of Metallic Alloys Biocompatibility" -- "Abstract" -- "1 Introduction" -- "2 In Vitro Assays to Evaluate Material Biocompatibility" -- "2.1 Cell Model Selection" -- "2.2 Cell Viability and Proliferation" -- "2.3 Adhesion and Morphology" -- "2.4 Osteoblast Differentiation" -- "2.5 Inflammatory Response" -- "3 Principal Causes of Toxicity" -- "3.1 Corrosion" -- "3.2 Surface" -- "4 Conclusions and Future Directions" -- "Acknowledgements" -- "Bibliography" -- "17 Determining the Biological Properties of Biomaterials In Vivo" -- "Abstract" -- "1 Introduction" -- "2 Hypersensitivity Reactions to Biomaterials" -- "2.1 Type I of Hypersensitivity Reactions" -- "2.2 Type IV of Hypersensitivity Reactions" -- "2.3 Hypersensitivity to Orthopedic Materials" -- "2.4 Hypersensitivity to Dental Materials" -- "2.5 Endovascular Devices" -- "3 Effects of Biomaterials to Implantation" -- "3.1 Injury" -- "3.2 Blood-Biomaterial Interactions" -- "3.3 Provisional Matrix Formation" -- "3.4 Inflammation" -- "3.5 Granulation Tissue" -- "3.6 The Foreign Body Reaction" -- "3.7 Fibrous Capsule Development and Fibrosis" -- "4 Conclusion" -- "Acknowledgements" -- "References" -- "18 Genotoxicity and Mutagenicity Testing of Biomaterials" -- "Abstract" -- "1 Introduction
    Content: "2 In Vitro Genotoxicity/Mutagenicity Testing
    Additional Edition: 9783319680248
    Additional Edition: Print version Zivic, Fatima Biomaterials in Clinical Practice : Advances in Clinical Research and Medical Devices Cham : Springer International Publishing,c2017 9783319680248
    Language: English
    URL: Volltext  (lizenzpflichtig)
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  • 5
  • 6
    UID:
    (DE-627)165672409X
    Edition: Online-Ausg. Dresden Saechsische Landesbibliothek - Staats- und Universitaetsbibliothek Dresden 2015 Online-Ressource
    Note: Aus: BioMed Research International, Volume 2013 (2013), Article ID 938368, 10 pages, ISSN: 2314-6133. - Elektron. Sonderdr.: Dresden : SLUB, 2015
    Language: English
    Subjects: Biology
    RVK:
    URL: Volltext  (kostenfrei)
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  • 7
  • 8
    UID:
    (DE-627)1657069095
    Format: 1 Online-Ressource
    Note: Sonderdruck aus: Scientific Reports (2017), 7(1), ISSN: 2045-2322. DOI: 10.1038/s41598-017-01264-8. Artikelnr.: 1210
    Language: English
    Subjects: Physics
    RVK:
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