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  • GBV  (8)
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  • 1
    Online Resource
    Online Resource
    Biochemistry of Collagens, Laminins and Elastin, 2nd : Structure, Function and Biomarkers (2019)
    San Diego : Elsevier Science & Technology
    Details
    UID:
    (DE-627)1673267769
    Format: 1 online resource (436 pages)
    Edition: 2nd ed.
    ISBN: 9780128170694
    Note: Description based on publisher supplied metadata and other sources
    Additional Edition: 9780128170687
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780128170687
    Language: English
    URL: lizenzpflichtig
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  • 2
    Online Resource
    Online Resource
    Biochemistry of Collagens, Laminins and Elastin : Structure, Function and Biomarkers (2023)
    San Diego : Elsevier Science & Technology
    Details
    UID:
    (DE-627)187057995X
    Format: 1 online resource (586 pages)
    Edition: 3rd ed.
    ISBN: 9780443156182
    Content: Front Cover -- Biochemistry of Collagens, Laminins and Elastin -- Biochemistry of Collagens, Laminins and Elastin Structure, Function and Biomarkers -- Copyright -- Contents -- List of contributors -- List of contributors -- Foreword -- Preface -- Acknowledgments -- List of abbreviations -- Introduction -- Why are collagens and structural proteins important? -- Introduction to the matrix-Interstitial and basement membranes -- Overall structure of collagens -- Collagen synthesis and other essentials -- The origin of collagens-Collagen phylogenetics -- Collagen turnover as function of age -- Why laminins? -- Understanding the epitope of a protein -- Why do we need to quantify the ECM? -- Propeptides -- Degradation fragments -- Tissue balance -- Signaling peptides -- Conclusion -- References -- The collagen history -- The diversity of the collagen family: Beyond the 28 collagen types -- Molecular and supramolecular assembly of collagens -- Collagens: A networking family in various contexts -- References -- 1 - Type I collagen -- References -- 2 - Type II collagen -- Soluble biomarkers of type II collagen -- References -- 3 - Type III collagen -- Biomarkers of type III collagen -- References -- 4 - Type IV collagen -- Composition and structure of type IV collagen -- Type IV collagen diseases -- Matrikines from the NC1 domains -- Biomarkers of type IV collagen -- References -- 5 - Type V collagen -- Autoimmunity -- Cardiovasuclar disease -- Cancer -- Biomarkers of type V collagen -- References -- 6 - Type VI collagen -- Biomarkers of type VI collagen -- References -- 7 - Type VII collagen -- Expression and function -- The role of COLVII in pathologies -- Soluble biomarkers of type VII collagen -- References -- 8 - Type VIII collagen -- Type VIII collagen -- Biomarkers of type VIII collagen -- References -- 9 - Type IX collagen.
    Note: Description based on publisher supplied metadata and other sources
    Additional Edition: 9780443156175
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780443156175
    Language: English
    URL: lizenzpflichtig
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  • 3
    Online Resource
    Online Resource
    Biochemistry of Collagens, Laminins and Elastin : Structure, Function and Biomarkers = Structure, Function and Biomarkers (2016)
    San Diego : Elsevier Science
    Details
    UID:
    (DE-627)865254036
    Format: 1 Online-Ressource (274 p)
    ISBN: 9780128098479
    Content: Front Cover -- Biochemistry of Collagens, Laminins and Elastin -- Biochemistry of Collagens, Laminins and Elastin: Structure, Function and Biomarkers -- Copyright -- Contents -- List of Contributors -- Preface -- Acknowledgments -- List of Abbreviations -- Introduction -- WHY ARE COLLAGENS AND STRUCTURAL PROTEINS IMPORTANT? -- INTRODUCTION TO THE MATRIX-INTERSTITIAL AND BASEMENT MEMBRANES -- OVERALL STRUCTURE OF COLLAGENS -- COLLAGEN SYNTHESIS AND OTHER ESSENTIALS -- COLLAGEN TURNOVER AS FUNCTION OF AGE -- WHY LAMININS? -- REFERENCES -- 1 - Type I Collagen -- BIOMARKERS OF TYPE I COLLAGEN
    Note: Description based upon print version of record
    Additional Edition: 9780128098998
    Additional Edition: Print version Karsdal, Morten Biochemistry of Collagens, Laminins and Elastin : Structure, Function and Biomarkers San Diego : Elsevier Science,c2016 9780128098479
    Language: English
    Keywords: Electronic books
    URL: Volltext
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    Online Resource
    Online Access
    GBV
  • 4
    Book
    Book
    Biochemistry of collagens, laminins and elastin : structure, function and biomarkers (2016)
    Amsterdam [u.a.] : Academic Press
    Details
    UID:
    (DE-627)1638428417
    Format: xxxiv, 238 Seiten , Illustrationen , 23 cm
    ISBN: 9780128098479
    Additional Edition: Erscheint auch als Online-Ausgabe Biochemistry of collagens, laminins, and elastin Amsterdam : Academic Press is an imprint of Elsevier, 2016 9780128098998
    Language: English
    Subjects: Medicine
    RVK:
    XG 9400
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  • 5
    Online Resource
    Online Resource
    Biochemistry of collagens, laminins and elastin : structure, function and biomarkers (2024)
    London : Academic Press
    Details
    UID:
    (DE-627)1886222851
    Format: 1 Online-Ressource (470 pages)
    Edition: Third edition
    ISBN: 0443156182 , 9780443156182
    Content: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens
    Note: Previous edition: London: Academic Press, 2019
    Additional Edition: 9780443156175
    Additional Edition: Erscheint auch als Druck-Ausgabe Karsdal, Morten A Biochemistry of collagens, laminins and elastin Amsterdam : Academic Press, 2023 9780443156175
    Language: English
    URL: lizenzpflichtig
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  • 6
    Online Resource
    Online Resource
    Biochemistry of collagens, laminins and elastin : structure, function and biomarkers (2019)
    London, United Kingdom : Academic Press, an imprint of Elsevier
    Details
    UID:
    (DE-627)1684642795
    Format: 1 Online-Ressource
    Edition: Second edition
    ISBN: 0128170697 , 9780128170694
    Content: Introduction -- Chapter 1. Type I collagen / K. Henriksen and M.A. Karsdal -- Chapter 2. Type II collagen / Y. He, N.S. Gudmann, ... C.S. Thudium -- Chapter 3. Type III collagen / M.J. Nielsen, I.F. Villesen, ... M.A. Karsdal -- Chapter 4. Type IV collagen / J.M.B. Sand, F. Genovese, ... M.A. Karsdal -- Chapter 5. Type V collagen / D.J. Leeming and M.A. Karsdal -- Chapter 6. Type VI collagen / S. Sun, F. Genovese and M.A. Karsdal -- Chapter 7. Type VII collagen / J.H. Mortensen and M.A. Karsdal -- Chapter 8. Type VIII collagen / N.U.B. Hansen, N.S. Gudmann and M.A. Karsdal -- Chapter 9. Type IX collagen / Y. He, S. Sardar and M.A. Karsdal -- Chapter 10. Type X collagen / Y. He, N.S. Gudmann, ... M.A. Karsdal -- Chapter 11. Type XI collagen / Y.Y. Luo, P.M. Szlarski, ... M.A. Karsdal -- Chapter 12. Type XII collagen / J.H. Mortensen, T. Manon-Jensen and M.A. Karsdal -- Chapter 13. Type XIII collagen / A.S. Siebuhr, C.S. Thudium and M.A. Karsdal -- Chapter 14. Type XIV collagen / M. Lindholm, T. Manon-Jensen and M.A. Karsdal -- Chapter 15. Type XV collagen / T. Manon-Jensen, A. Arvanitidis and M.A. Karsdal -- Chapter 16. Type XVI collagen / J.M.B. Sand, C. Jensen and M.A. Karsdal -- Chapter 17. Type XVII collagen / S. Sun and M.A. Karsdal -- Chapter 18. Type XVIII collagen / M. Pehrsson, C.L. Bager and M.A. Karsdal -- Chapter 19. Type XIX collagen / S. Holm Nielsen and M.A. Karsdal -- Chapter 20. Type XX collagen / N. Willumsen, N.I. Nissen and M.A. Karsdal -- Chapter 21. Type XXI collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal -- Chapter 22. Type XXII collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal -- Chapter 23. Type XXIII collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal -- Chapter 24. Type XXIV collagen / S. Holm Nielsen and M.A. Karsdal -- Chapter 25. Type XXV collagen / L.L. Langholm, N.G. Kjeld and M.A. Karsdal -- Chapter 26. Type XXVI collagen / T. Manon-Jensen, N.G. Kjeld and M.A. Karsdal -- Chapter 27. Type XXVII collagen / F. Genovese and M.A. Karsdal -- Chapter 28. Type XXVIII collagen / N. Sparding, A. Arvanitidis and M.A. Karsdal -- Chapter 29. Laminins / D.G.K. Rasmussen and M.A. Karsdal -- Chapter 30. Elastin / J.H. Kristensen, J. Thorlacius-Ussing, ... M.A. Karsdal -- Chapter 31. The collagen chaperones / S.N. Kehlet, A.S. Siebuhr, ... M.A. Karsdal -- Chapter 32. Collagen diseases / S. Sardar, M.A. Karsdal and K. Henriksen -- Chapter 33. The signals of the extracellular matrix / A.L. Reese-Petersen, F. Genovese and M.A. Karsdal -- Chapter 34. The roles of collagens in cancer / N. Willumsen, N.I. Nissen and M.A. Karsdal -- Chapter 35. Use of extracellular matrix biomarkers in clinical research / A.R. Bihlet, M.A. Karsdal, ... C.L. Bager -- Chapter 36. Common confounders when evaluating noninvasive protein biomarkers / N. Willumsen, M.A. Karsdal and A. Kerrn-Jespersen -- Chapter 37. Implementation of collagen biomarkers in the clinical setting / E. Erhardtsen, D.G.K. Rasmussen and M.A. Karsdal.
    Content: There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease
    Note: Includes bibliographical references and index
    Additional Edition: 9780128170687
    Additional Edition: Erscheint auch als Druck-Ausgabe 0128170689
    Additional Edition: 9780128170687
    Language: English
    Keywords: Electronic books
    URL: lizenzpflichtig
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  • 7
    Online Resource
    Online Resource
    Biochemistry of collagens, laminins, and elastin : structure, function and biomarkers (2016)
    Amsterdam : Academic Press is an imprint of Elsevier
    Details
    UID:
    (DE-627)879399139
    Format: 1 Online-Ressource (xxxiv, 235 Seiten) , Illustrationen
    Edition: Online-Ausg.
    ISBN: 9780128098998
    Content: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease
    Note: Includes index. - Print version record
    Additional Edition: 9780128098479
    Additional Edition: Erscheint auch als Druck-Ausgabe Biochemistry of collagens, laminins and elastin Amsterdam [u.a.] : Academic Press, 2016 9780128098479
    Language: English
    Subjects: Medicine
    RVK:
    XG 9400
    Keywords: Biochemie ; Kollagen ; Laminin ; Elastin ; Electronic books ; Electronic books
    URL: Volltext
    URL: lizenzpflichtig
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    Online Access
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  • 8
    Online Resource
    Online Resource
    Biochemistry of collagens, laminins and elastin : structure, function and biomarkers (2016)
    Amsterdam : Elsevier
    Details
    UID:
    (DE-627)174557090X
    Format: 1 online resource (274 pages) , color illustrations
    ISBN: 9780128098998
    Content: Front Cover -- Biochemistry of Collagens, Laminins and Elastin -- Biochemistry of Collagens, Laminins and Elastin: Structure, Function and Biomarkers -- Copyright -- Contents -- List of Contributors -- Preface -- Acknowledgments -- List of Abbreviations -- Introduction -- WHY ARE COLLAGENS AND STRUCTURAL PROTEINS IMPORTANT? -- INTRODUCTION TO THE MATRIX-INTERSTITIAL AND BASEMENT MEMBRANES -- OVERALL STRUCTURE OF COLLAGENS -- COLLAGEN SYNTHESIS AND OTHER ESSENTIALS -- COLLAGEN TURNOVER AS FUNCTION OF AGE -- WHY LAMININS? -- REFERENCES -- 1 - Type I Collagen -- BIOMARKERS OF TYPE I COLLAGEN -- REFERENCES -- 2 - Type II Collagen -- BIOMARKERS OF TYPE II COLLAGEN -- REFERENCES -- 3 - Type III Collagen -- BIOMARKERS OF TYPE III COLLAGEN -- REFERENCES -- 4 - Type IV Collagen -- BIOMARKERS OF TYPE IV COLLAGEN -- REFERENCES -- 5 - Type V Collagen -- BIOMARKERS OF TYPE V COLLAGEN -- REFERENCES -- 6 - Type VI Collagen -- BIOMARKERS OF TYPE VI COLLAGEN -- REFERENCES -- 7 - Type VII Collagen -- REFERENCES -- 8 - Type VIII Collagen -- BIOMARKERS OF TYPE VIII COLLAGEN -- REFERENCES -- 9 - Type IX Collagen -- BIOMARKERS OF TYPE IX COLLAGEN -- REFERENCES -- 10 - Type X Collagen -- BIOMARKERS OF TYPE X COLLAGEN -- REFERENCES -- 11 - Type XI Collagen -- REFERENCES -- 12 - Type XII Collagen -- REFERENCES -- 13 - Type XIII Collagen -- BIOMARKERS OF TYPE XIII COLLAGEN -- REFERENCES -- 14 - Type XIV Collagen -- REFERENCES -- 15 - Type XV Collagen -- REFERENCES -- 16 - Type XVI Collagen -- BIOMARKERS OF TYPE XVI COLLAGEN -- REFERENCES -- 17 - Type XVII Collagen -- REFERENCES -- 18 - Type XVIII Collagen -- ROLE OF ENDOSTATIN IN BIOLOGY AND PATHOLOGY -- BIOMARKERS OF ENDOSTATIN -- REFERENCES -- 19 - Type XIX Collagen -- BIOMARKERS OF TYPE XIX COLLAGEN -- REFERENCES -- 20 - Type XX Collagen -- REFERENCES -- 21 - Type XXI Collagen -- BIOMARKERS OF TYPE XXI COLLAGEN.
    Note: Description based on online resource; title from PDF title page (ebrary, viewed August 24, 2016). Includes index
    Additional Edition: 9780128098479
    Additional Edition: Erscheint auch als Druck-Ausgabe 9780128098479
    Language: English
    URL: lizenzpflichtig
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    Online Resource
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