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  • 1989  (12)
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  • 1989  (12)
  • 1
    Language: English
    In: Journal of the American Geriatrics Society, September 1989, Vol.37(9), pp.913-4
    Keywords: Mass Screening ; Neoplasms -- Prevention & Control
    ISSN: 0002-8614
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  • 2
    Language: English
    In: Arthritis & Rheumatism, December 1989, Vol.32(12), pp.1577-1583
    Description: After we assessed the functional status of 439 patients with osteoarthritis, we randomly assigned them to 1 of 3 intervention groups or to a control group. The interventions consisted of providing information, and differed only in the method of delivery: by phone, in person at the clinic, or both. Physical health improved ( = 0.02), pain was reduced ( = 0.02), and psychological health improved marginally ( = 0.10) in patients contacted by phone compared with those not contacted by phone. In those contacted only at the clinic, physical health worsened ( = 0.02), but neither pain ( = 0.80) nor psychological health ( = 0.90) differed from the values in patients not contacted at the clinic. We conclude that telephone contact is a useful intervention that can enhance the functional status of patients with osteoarthritis.
    Keywords: Medical Social Work -- Evaluation ; Osteoarthritis -- Care And Treatment ; Patients ; Information Services;
    ISSN: 0004-3591
    E-ISSN: 1529-0131
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  • 3
    In: M.D. Computing, Jan-Feb, 1989, Vol.6(1), p.38(4)
    Description: MEDLOG ($6,500 for one copy; three or more are $3,500 each), from Information Management Corp, is a data management software package for entry, storage and management of medical data. The program is easy for physicians or healthcare personnel to use. Specific uses include clinical trials, longitudinal studies and data registries. MEDLOG requires an IBM or a compatible, with a floppy drive and a hard disk with a minimum of 10Mbytes. The system requires 512Kbytes of RAM and DOS 2.0 or higher. MEDLOG is available on either 5.25-inch or 3.5-inch disks. Installing MEDLOG is simple, involving merely copying seven distribution disks onto a subdirectory on a hard disk. There are two tutorial disks that also should be placed on the hard disk. MEDLOG is among the best data management systems.
    Keywords: Dbms Software ; Medicine ; Evaluation ; Information Analysis Corp.
    ISSN: 0724-6811
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  • 4
    Language: English
    In: Arthritis & Rheumatism, January 1989, Vol.32(1), pp.45-53
    Description: Fifteen patients with Wegener's granulomatosis, polyarteritis nodosa, or isolated angiitis of the central nervous system were treated with cyclophosphamide according to a widely used regimen. Seventeen clinical episodes of infection were observed over 201 patient‐months of cyclophosphamide therapy, and 2 patients died of pneumonia. Notably, neither the incidence of leukopenia nor the dosage or duration of cyclophosphamide or corticosteroid therapy correlated well with infection, which occurred most frequently in men over 60 years of age. Patients with Wegener's granulomatosis appeared to be at greater risk of infection than those with the other forms of vasculitis. These results suggest that this treatment regimen may not be as safe as was previously thought.
    Keywords: Bacterial Infections -- Etiology ; Cyclophosphamide -- Adverse Effects ; Vasculitis -- Drug Therapy ; Virus Diseases -- Etiology;
    ISSN: 0004-3591
    E-ISSN: 1529-0131
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  • 5
    Language: English
    In: The Journal of Infectious Diseases, 1 April 1989, Vol.159(4), pp.661-669
    Description: To determine whether concurrent gonorrhea reactivates latent chlamydial infection, we studied 74 recurrent chlamydial infections and the effect of concurrent gonorrhea at the recurrent episode on the chlamydial serovar identified. Serotyping of 74 recurrent pairs of chlamydial isolates from patients attending a sexually transmitted diseases clinic indicated that 47.1% (16 of 34) with gonorrhea at the time of recurrence harbored chlamydiae of the same serovar as at the initial infection, while only 22.5% (9 of 40) without gonorrhea had the same serovar (P = .03). The proportion of recurrences by the same serovar in the group without gonorrhea did not differ from the proportion predicted by a random exposure model (22.2% vs. 18.4%, P = .46), while the proportion in the gonorrhea group did (47.1% vs. 19.8% P 〈 .0001). The possibility of reinfection did not appear more likely in the group with gonorrhea than in the group without. These observations support the hypothesis that concurrent gonorrhea can reactivate latent chlamydial infection.
    Keywords: Health sciences -- Medical conditions -- Infections ; Health sciences -- Medical conditions -- Infections ; Biological sciences -- Biology -- Microbiology ; Health sciences -- Medical sciences -- Immunology ; Health sciences -- Medical conditions -- Diseases ; Health sciences -- Medical sciences -- Immunology ; Health sciences -- Medical conditions -- Diseases ; Health sciences -- Medical conditions -- Infections ; Social sciences -- Population studies -- Human populations ; Biological sciences -- Biology -- Anatomy
    ISSN: 00221899
    E-ISSN: 15376613
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  • 6
    Language: English
    In: Arthritis & Rheumatism, December 1989, Vol.32(12), pp.1626-1627
    Keywords: Cyclophosphamide -- Adverse Effects ; Infection -- Etiology ; Vasculitis -- Drug Therapy;
    ISSN: 0004-3591
    E-ISSN: 1529-0131
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  • 7
    Language: English
    In: The Journal of Infectious Diseases, 1 August 1989, Vol.160(2), pp.332-336
    Description: The relationship between acute inflammation and serovar of Chlamydia trachomatis was evaluated in patients with genital chlamydial infection who attended a sexually transmitted diseases clinic. Polymorphonuclear leukocytes (PMNLS) were enumerated on Gram's stained smears of endourethral contents in men; cervicitis was scored by visual observation of the endocervix in women. Isolates were serotyped with a monoclonal antibody-based radioimmunoassay. The distribution of serovars in 99 women did not differ in the presence or absence of cervicitis or concurrent gonorrhea. An overall difference (P = .037) was observed when serovar distributions in men with lt;3 PMNLs (n = 42), gt;10 PMNLs (n = 41), and gonococcal urethritis (n = 42) were compared. Follow-up pairwise comparisons revealed that men with lt;3 PMNLs had fewer isolates of serovars F and G than did men with gt;10 PMNLs (P 〈.05). No strong overall association was observed between inflammation and serovar.
    Keywords: Health sciences -- Medical conditions -- Diseases -- Monoclonal antibodies ; Biological sciences -- Biology -- Anatomy -- Monoclonal antibodies ; Health sciences -- Medical conditions -- Infections -- Monoclonal antibodies ; Biological sciences -- Biology -- Microbiology -- Monoclonal antibodies ; Health sciences -- Medical sciences -- Immunology -- Monoclonal antibodies ; Health sciences -- Medical sciences -- Immunology -- Monoclonal antibodies ; Social sciences -- Population studies -- Human populations -- Monoclonal antibodies ; Health sciences -- Medical conditions -- Infections -- Monoclonal antibodies ; Health sciences -- Medical conditions -- Diseases -- Monoclonal antibodies ; Health sciences -- Medical sciences -- Immunology -- Monoclonal antibodies
    ISSN: 00221899
    E-ISSN: 15376613
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  • 8
    In: Sexually Transmitted Diseases, 1989, Vol.16(2), pp.103-106
    Description: The present study was undertaken to evaluate the utility of a gram stain of endocervical secretions in the prediction of endocervical infection with Chlamydia trachomatis. Endocervical examinations, Gram stains and chlamydial cultures were performed on 214 women who were attending a sexually transmitted diseases clinic and were at increased risk for chlamydial infection. Almost 24% of the Gram stains were judged inadequate because of the presence of ectocervical material. However, significantly higher isolation rates for C. trachomatis were found for those women with valid smears and 10 or more polymorphonuclear cells on their smear (44% vs 19%, P = .0008). This relationship was independent of the presence of gonococcal infection. Based on the results of this study, endocervical Gram stains appear to be a valuable screening tool for chlamydial infection, particularly among those without mucopurulent discharge.
    Keywords: Chlamydia Infections -- Diagnosis ; Uterine Cervicitis -- Diagnosis;
    ISSN: 0148-5717
    E-ISSN: 15374521
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  • 9
    Language: English
    In: Statistics in Medicine, February 1989, Vol.8(2), pp.229-241
    Description: We have derived the variance of an expected utility for a probability tree in medical decision analysis based on a Taylor series approximation of the expected utility as a function of the probability and utility values used in the decision tree. The resulting variance estimate is an algebraic expression of the variances associated with the probability and utility estimates used. We also derive expressions for the case where the input parameter estimates are not independent. We discuss the choice of input parameters and their variance estimates and give an example that compares two protocols for the treatment of chlamydial infection.
    Keywords: Medical Decision Analysis ; Decision Trees ; Variance Estimation
    ISSN: 0277-6715
    E-ISSN: 1097-0258
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  • 10
    Language: English
    In: The Journal of the American Dental Association, January 1989, Vol.118(1), pp.41-45
    Description: Fifty private practitioners and their office staff members were randomly assigned to one of four groups: participants received a protocol for smoking management and a lecture on the consequences and management of smoking, or in addition, had nicotine gum freely available to patients, had stickers attached to their charts, or had gum and reminders. The percentage of patients in each group who had quit smoking a year later was 7.7, 16.3, 8.6, and 16.9, respectively, indicating a significant main effect for the gum conditions. The availability of nicotine gum also significantly increased the amount of time that patients reported they received smoking cessation counseling from the dentists and office staff.
    Keywords: Dentistry
    ISSN: 0002-8177
    E-ISSN: 1943-4723
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