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  • 1
    Language: English
    In: Soil Science Society of America journal, 2008, Vol.72(6), pp.1694-1707
    Description: Proton nuclear magnetic resonance (1H NMR) relaxometry has been used to analyze pore size distributions of wet porous samples. To make this method applicable to soil samples, knowledge about contribution from the soil solution to the total proton relaxation is needed. We extracted soil solutions from nine soil samples and determined transverse proton relaxation rates, the concentration of Fe, Mn, and total organic C (TOC), and the pH of the solutions. The effects of Fe, Mn, and TOC on the proton relaxation in the soil solution were compared with those of dissolved Fe2+, Fe3+, and Mn2+ and of glucose, D-cellobiose, potassium hydrogen phthalate, sodium alginate, and agar in model solutions. Proton relaxation rates in the soil solutions were up to 20 times larger than in pure water, which was mainly due to dissolved Fe(III) and Mn(II) species. The relaxivities of Fe and Mn in soil solution were reduced to 40 and 70% compared with Fe(III) and Mn(II) in a model solution, respectively. Smaller relaxivities were primarily due to the formation of metal-organic complexes. We conclude that the proton relaxation in soil samples is generally accelerated by the soil solution, and its contribution must be considered to estimate pore sizes from relaxation times. By using the calculated relaxivities of Fe and Mn in soil solution, the contribution of the soil solution to the total proton relaxation can be estimated from the Fe and Mn concentration in the soil solution. ; Includes references ; p. 1694-1707.
    Keywords: Soil Organic Carbon ; Goethite ; Cellobiose ; Soil Solution ; Agar ; Soil Pore System ; Manganese ; Ions ; Iron ; Colloids ; Sampling ; Alginates ; Glucose ; Extracts ; Chemical Concentration ; Chemical Composition ; Nuclear Magnetic Resonance Spectroscopy ; Montmorillonite ; Sodium Alginate ; Pore Size Distribution ; Proton Relaxation ; Potassium Hydrogen Phthalate
    ISSN: 0361-5995
    E-ISSN: 14350661
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  • 2
    Language: English
    In: American Journal of Hematology, May 2008, Vol.83(5), pp.382-386
    Description: In patients with acute leukemia, Wilms' tumor gene 1 (WT1) has been used as a target for the detection of minimal residual disease (MRD) by PCR techniques. The expression of WT1 protein, however, has not been extensively studied. To determine the relation between expression of WT1 transcripts and of the encoded protein, we examined leukemic cell lines and primary childhood leukemia samples using both real‐time quantitative PCR (RQ‐PCR) and flow cytometry. WT1 protein was highly expressed in the leukemic cell lines K562, HL‐60, PLB 985, KG‐1a and CEM. By contrast, 40 primary samples of acute lymphoblastic leukemia (ALL; B‐ALL, = 15 and T‐ALL, = 10) and acute myeloid leukemia ( = 15) expressed low levels of WT1 protein. RQ‐PCR detected WT1 transcript levels in the same range as reported in earlier studies in childhood acute leukemia. The results of this study indicate the following: (i) there are considerable discrepancies between WT1 transcripts and protein expression; (ii) WT1 is not a suitable marker for flow cytometric MRD detection in childhood acute leukemia. Am. J. Hematol., 2008. © 2007 Wiley‐Liss, Inc.
    Keywords: Gene Expression Regulation, Leukemic ; Neoplasm Proteins -- Analysis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma -- Metabolism ; Wt1 Proteins -- Analysis;
    ISSN: 0361-8609
    E-ISSN: 1096-8652
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  • 3
    Language: German
    Description: Eine aktuelle und fundierte Didaktik für den Unterricht mit blinden oder hochgradig sehbehinderten Schülerinnen und Schülern fehlt seit langem. Für diese Zielgruppe sind vielfältige, spezifische didaktische Notwendigkeiten zu berücksichtigen. Dieser Band thematisiert die speziellen Lernvoraussetzungen blinder und hochgradig sehbehinderter Schülerinnen und Schüler und leitet daraus eine spezifische Didaktik ab. Inhalte, Methoden und Organisationsformen des Unterrichts finden ebenso eine ausführliche Darstellung wie die grundlegenden Förderbereiche....
    Keywords: Behindertenpädagogik
    ISBN: ISBN 978-3-17-20150-7
    Source: DataCite
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