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  • 1
    Language: English
    In: European Journal of Radiology, June 2016, Vol.85(6), pp.1058-1062
    Description: To evaluate a novel tin filter-based abdominal CT protocol for urolithiasis in terms of image quality and CT dose parameters. 130 consecutive patients with suspected urolithiasis underwent CT with three different protocols: 48 patients (group 1) were examined at tin-filtered 150 kV (150 kV Sn) on a third-generation dual-source-CT, 33 patients were examined with automated kV-selection (110–140 kV) based on the scout view on the same CT-device (group 2), and 49 patients were examined on a second-generation dual-source-CT (group 3) with automated kV-selection (100–140 kV). Automated exposure control was active in all groups. Image quality was subjectively evaluated on a 5-point-likert-scale by two radiologists and interobserver agreement as well as signal-to-noise-ratio (SNR) was calculated. Dose-length-product (DLP) and volume CT dose index (CTDIvol) were compared. Image quality was rated in favour for the tin filter protocol with excellent interobserver agreement (ICC = 0.86–0.91) and the difference reached statistical significance (p 〈 0.001). SNR was significantly higher in group 1 and 2 compared to second-generation DSCT ( ). On third-generation dual-source CT, there was no significant difference in SNR between the 150 kV Sn and the automated kV selection protocol (p = 0.5). The DLP of group 1 was 23% and 21% (p 〈 0.002) lower in comparison to group 2 and 3, respectively. So was the CTDIvol of group 1 compared to group 2 (−36%) and 3 (−32%) (p 〈 0.001). Additional shaping of a 150 kV source spectrum by a tin filter substantially lowers patient exposure while improving image quality on un-enhanced abdominal computed tomography for urinary stone disease.
    Keywords: Low-Dose Abdominal CT ; Urinary Stone Disease ; Spectral Shaping ; Tin Filter ; Medicine
    ISSN: 0720-048X
    E-ISSN: 1872-7727
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  • 2
    Language: English
    In: European Journal of Radiology, November 2015, Vol.84(11), pp.2052-2058
    Description: To evaluate a novel monoenergetic reconstruction algorithm (nMERA) with improved noise reduction for dual-energy CT (DECT) of pancreatic adenocarcinoma. Sixty patients with suspected pancreatic carcinoma underwent dual-source dual-energy CT with arterial phase. Images were reconstructed as linearly-blended 120-kV series (M_0.6) and with the standard monoenergetic (sMERA) and the novel monoenergetic algorithm (nMERA) with photon energies of 40, 55, 70 and 80 keV. Objective image quality was compared regarding image noise, pancreas attenuation, signal-to-noise ratio (SNR) and pancreas-to-lesion contrast. Subjective image quality was assessed by two observers. Thirty pancreatic adenocarcinomas were detected. nMERA showed significantly reduced image noise at low keV levels compared with sMERA images (55 keV: 7.19 ± 2.75 vs. 20.68 ± 7.01HU; 40 keV: 7.33 ± 3.20 vs. 37.22 ± 14.66HU) and M_0.6 (10.69 ± 3.57HU). nMERA pancreatic SNR was significantly superior to standard monoenergetic at 40 (47.02 ± 23.41 vs. 9.37 ± 5.83) and 55 keV (28.29 ± 16.86 vs. 9.88 ± 7.01), and M_0.6 series (11.42 ± 6.00). Pancreas-to-lesion contrast peaked in the nMERA 40 keV series (26.39 ± 16.83) and was significantly higher than in all other series ( 〈 0.001). nMERA 55 keV images series were consistently preferred by both observers over all other series ( 〈 0.01). nMERA DECT can significantly improve image quality and pancreas-to-lesion contrast in the diagnosis of pancreatic adenocarcinoma.
    Keywords: Dual-Energy CT ; Monoenergetic Reconstruction ; Pancreatic Adenocarcinoma ; Tumor Contrast ; Lesion Conspicuity ; Medicine
    ISSN: 0720-048X
    E-ISSN: 1872-7727
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