UID:
almahu_9949616712402882
Format:
VIII, 296 p.
,
online resource.
Edition:
1st ed. 2023.
ISBN:
9783031399442
Series Statement:
Cancer Immunotherapy, 2
Content:
This book provides an overview of the available evidence surrounding immunotherapy in gastrointestinal cancers, and discusses its future place in clinical practice. Immunotherapy has celebrated some astonishing therapeutic successes in a variety of cancer types and is becoming increasingly relevant in daily clinical practice. Currently, the predominant class of immunotherapeutic drugs is the so-called checkpoint inhibitors, which disengage the physiological brakes on the immune system, enabling a more effective anti-cancer immune response. Malignancies of the gastrointestinal tract, which account for the majority of cancer cases worldwide, are a major cause of morbidity and mortality, creating an urgent need for more effective therapies. A large number of clinical trials have evaluated the efficacy of cancer immunotherapy in gastrointestinal malignancies and demonstrated its potential in certain subsets of patients. This book will appeal to a wide readership, including oncologists, health care professionals in general and biomedical scientists.
Note:
Part I Role of the Tumor Microenvironment -- An Overview of the Tumor Microenvironment and Response to Immunotherapy in Gastrointestinal Malignancies -- Part II Esophagus -- Approach to Immunotherapy in Oesophageal Cancer -- Perspective on the Immunotherapy of Esophageal Cancer -- Part III Stomach -- Immunotherapy of Gastric Cancer: Focus on Perioperative Strategies -- Stomach: The Standard of Care ± HER2 -- Perspective on the Immunotherapy of Gastric Cancer -- Part IV Colon -- Immunotherapy in dMMR/MSI-H Colon Cancer -- Immunotherapy in the Treatment of Advanced Colorectal Cancer -- Immunotherapy of Rectal Cancer -- Perspective on Immunotherapy of Colon Cancer: Challenges for the Future -- Part V HCC -- Immune Strategies for Gastrointestinal Cancer: HCC -- Immunotherapy in GI Cancers: Hepatocellular Carcinoma: Perspective -- Part VI Biliary Tract -- Immunotherapy of Biliary Tract Cancer -- Perspective on Immunotherapy Use in Biliary Tract Cancer -- Part VII Pancreas -- Immune Landscape of Pancreas Ductal Adenocarcinoma: Current Therapeutic Strategies and Future Perspective -- Perspective on the Immunotherapy of Pancreatic Cancer -- Part VIII Biomarkers for Immunotherapy in Gastrointestinal Cancers -- Biomarkers for Immunotherapy in Gastrointestinal Cancers.
In:
Springer Nature eBook
Additional Edition:
Printed edition: ISBN 9783031399435
Additional Edition:
Printed edition: ISBN 9783031399459
Language:
English
DOI:
10.1007/978-3-031-39944-2
URL:
https://doi.org/10.1007/978-3-031-39944-2
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