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  • 1
    Language: English
    In: Microelectronics Reliability, September 2013, Vol.53(9-11), pp.1681-1686
    Description: In the past the main focus for improvements in power electronic modules was on chip technology. Therefore, looking at the cross section structure of modern modules, only small improvements have been made in recent decades. The reason for this is that the design and joining technology satisfied the market requirements. Furthermore the power electronic market segment is smaller than the one for microelectronic devices. Therefore it had to use their existing production facilities, e.g. bond wire machines. In the future this will change because of the following reasons: 1) Power electronic performance depends by a high ratio on package technology 2) The automotive industry has high requirements regarding cost efficiency, reliability and compactness. Furthermore they have big lever for innovations to make a product fit this requirement. Power electronic devices are used in (hybrid) electric vehicles ((H)EVs). 3) Dies in future will require new package technologies, especially when a wide band gap (WBG) material like silicon carbide (SiC) or gallium nitride (GaN) is used. Therefore there is a need for a paradigm shift in package technology to make use of a junction temperature above 200°C possible while reliability and cost performance have increased. This article will give an overview of the current available technologies and present Fuji’s new package solution ideas.
    Keywords: Engineering
    ISSN: 0026-2714
    E-ISSN: 1872-941X
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  • 2
    Language: English
    In: Microelectronics Reliability, September 2014, Vol.54(9-10), pp.1901-1905
    Description: For the task of improving the reliability and robustness of power electronic semiconductor devices, the main focus is on packaging and joining technology. The improvement is made necessary by various applications which require higher active and passive temperature cycles capability. For example: Automotive applications require a minimum life time of 15 years, wind power 25 and traction applications, 30–40 years and longer. Furthermore, higher reliability is demanded of new semiconductor technology, because maximum junction temperatures will, sooner or later, exceed currently recognized limits. In the near future, silicon devices will reach a maximum junction temperature of up to 200 °C. And the new wideband-gap devices have the potential to exceed even this limit. That is why a new package and joining technology is mandatory. There are new developments in the pipeline: For the die contact, planar wire technology and copper based bond wires can be expected in the long term. This new technology is based on new material science and printed circuit board process techniques. As a robust joining method, sinter or diffusion solder will be in use soon. But on the semiconductor module level, further action can be taken now, or in the near future, to increase reliability significantly. This paper presents improvements, based on material science, which are already available and can be used now, or in the near future.
    Keywords: Power ; Electronic ; Packaging ; Joining ; Material ; Microstructure ; Engineering
    ISSN: 0026-2714
    E-ISSN: 1872-941X
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  • 3
    In: Pigment Cell & Melanoma Research, September 2015, Vol.28(5), pp.488-489
    Description: To purchase or authenticate to the full-text of this article, please visit this link: http://onlinelibrary.wiley.com/doi/10.1111/pcmr.12389/abstract Byline: Peter Dietrich, Anja Katrin Bosserhoff ***** No abstract is available for this article. ***** Article Note: Coverage on: Shoshan E, Mobley AK, Braeuer RR, Kamiya T, Huang L, Vasquez ME, Salameh A, Lee HJ, Kim SJ, Ivan C, Velazquez-Torres G, Nip KM, Zhu K, Brooks D, Jones SJ, Birol I, Mosqueda M, Wen YY, Eterovic AK, Sood AK, Hwu P, Gershenwald JE, Robertson AG, Calin GA, Markel G, Fidler IJ, Bar-Eli M. (2015) Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nat. Cell Biol. 17(3), 311-321. doi: 10.1038/ncb3110.
    Keywords: Melanoma ; Microrna;
    ISSN: 1755-1471
    E-ISSN: 1755-148X
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  • 4
    Language: English
    In: Best Practice & Research Clinical Gastroenterology, August 2014, Vol.28(4), pp.637-653
    Description: Nonalcoholic fatty liver disease (NAFLD) is now recognized as the most common cause of chronic liver disease worldwide. Its prevalence has increased to more than 30% of adults in developed countries and its incidence is still rising. The majority of patients with NAFLD have simple steatosis but in up to one third of patients, NAFLD progresses to its more severe form nonalcoholic steatohepatitis (NASH). NASH is characterized by liver inflammation and injury thereby determining the risk to develop liver fibrosis and cancer. NAFLD is considered the hepatic manifestation of the metabolic syndrome. However, the liver is not only a passive target but affects the pathogenesis of the metabolic syndrome and its complications. Conversely, pathophysiological changes in other organs such as in the adipose tissue, the intestinal barrier or the immune system have been identified as triggers and promoters of NAFLD progression. This article details the pathogenesis of NAFLD along with the current state of its diagnosis and treatment.
    Keywords: Nonalcoholic Fatty Liver Disease (Nafld) ; Nonalcoholic Steatohepatitis (Nash) ; Metabolic Syndrome ; Medicine
    ISSN: 1521-6918
    E-ISSN: 1532-1916
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  • 5
    In: Pigment Cell & Melanoma Research, May 2018, Vol.31(3), pp.350-351
    Description: Byline: Peter Dietrich,Anja Katrin Bosserhoff ***** No abstract is available for this article. ***** Article Note: Coverage on: Gilot, D., Migault, M., Bachelot, L., Journe, F., Rogiers, A., Donnou-Fournet, E., Mogha, A., Mouchet, N., Pinel-Marie, M.-L., Mari, B., Montier, T., Corre, S., Gautron, A., Rambow, F., El Hajj, P., Ben Jouira, R., Tartare-Deckert, S., Marine, J.-C., Felden, B., Ghanem, G., Galibert, M.-D. (2017). A noncoding function of TYRP1 mRNA promotes melanoma growth. Nature Cell Biology Oct 9. https://doi.org/10.1038/ncb3623.
    Keywords: Tumors ; Melanoma ; Cells (Biology) ; Microrna;
    ISSN: 1755-1471
    E-ISSN: 1755-148X
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  • 6
    In: Pigment Cell & Melanoma Research, July 2016, Vol.29(4), pp.399-401
    Description: Byline: Peter Dietrich, Anja Katrin Bosserhoff ***** No abstract is available for this article. ***** Article Note: Coverage on: Micevic, G., Muthusamy, V., Damsky, W., Theodosakis, N., Liu, X., Meeth, K., Wingrove, E., Santhanakrishnan, M., and Bosenberg, M. (2016). DNMT3b modulates melanoma growth by controlling levels of mTORC2 component RICTOR. Cell Rep. 14(9), 2180-2192.
    Keywords: DNA (Cytosine-5-)-Methyltransferases–Physiology ; Humans–Physiology ; Mechanistic Target of Rapamycin Complex 2–Physiology ; DNA (Cytosine-5-)-Methyltransferases ; DNA Methyltransferase 3b ; Mechanistic Target of Rapamycin Complex 2;
    ISSN: 1755-1471
    E-ISSN: 1755-148X
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  • 7
    Language: English
    In: Journal of Hydrology, Sept 19, 2014, Vol.517, p.54(10)
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jhydrol.2014.05.003 Byline: Falk Handel, Gaisheng Liu, Peter Dietrich, Rudolf Liedl, James J. Butler Abstract: acents Small-diameter direct-push (DP) wells are a viable ASR recharge approach. acents Two 0.05-m shallow vadose-zone wells have a larger recharge rate than a 60m.sup.2 basin. acents Near-surface, low K-layers have a small impact on the well recharge capacity. acents DP well has a strong dependence on the horizontal component of hydraulic conductivity. Article History: Received 10 January 2014; Revised 3 May 2014; Accepted 4 May 2014 Article Note: (miscellaneous) This manuscript was handled by Peter K. Kitanidis, Editor-in-Chief, with the assistance of Ty Ferre, Associate Editor
    Keywords: Hydrogeology -- Analysis
    ISSN: 0022-1694
    Source: Cengage Learning, Inc.
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  • 8
    Language: English
    In: The Journal of Urology, April 2016, Vol.195(4), pp.e744-e745
    Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.juro.2016.02.613 Byline: Michael Avallone, Peter Dietrich, Shanta Shepherd, Mona Lalehzari, R. Corey O'Connor, Michael Guralnick Author Affiliation: Milwaukee, WI Article Note: (footnote) Source of Funding: None
    Keywords: Medicine
    ISSN: 0022-5347
    E-ISSN: 1527-3792
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  • 9
    Language: English
    In: Journal of Hydrology, March 2016, Vol.534, pp.113-123
    Description: The ongoing transition from fossil fuels to alternative energy source provision has resulted in increased geothermal uses as well as storage of the shallow subsurface. Existing approaches for exploration of shallow subsurface geothermal energy storage often lack the ability to provide information concerning the spatial variability of thermal storage parameters. However, parameter distributions have to be known to ensure that sustainable geothermal use of the shallow subsurface can take place – especially when it is subject to intensive usage. In this paper, we test a temperature decay time approach to obtain , direct, qualitative, spatial high-resolution information about the distribution of thermal storage capabilities of the shallow subsurface. To achieve this, temperature data from a high-resolution Fibre-Optic-Distributed-Temperature-Sensing device, as well as data from conventional Pt -temperature-sensors were collected during a heat injection test. The latter test was used to measure the decay time of temperature signal dissipation of the subsurface. Signal generation was provided by in-aquifer heating with a temperature self-regulating electric heating cable. Heating was carried out for 4.5 days. After this, a cooling period of 1.5 weeks was observed. Temperature dissipation data was also compared to Direct-Push-derived high-resolution (hydro-)geological data. The results show that besides hydraulic properties also the bedding and compaction state of the sediment have an impact on the thermal storage capability of the saturated subsurface. The temperature decay time approach is therefore a reliable method for obtaining information regarding the qualitative heat storage capability of heterogeneous aquifers for the use with closed loop system geothermal storage systems. Furthermore, this approach is advantageous over other commonly used methods, e.g. soil-sampling and laboratory analysis, as even small changes in (hydro-)geological properties lead to strong variances in observed heat-storage capabilities at the investigated case study site. By using fibre-optic-thermometers, nearly every requested spatial resolution can be achieved and easily be adjusted to the needs of actual test sites for shallow geothermal storage exploration.
    Keywords: Distributed-Temperature-Sensing ; Shallow Subsurface Thermal-Storage ; Shallow Geothermal Exploration ; Direct-Push in Situ Investigations ; Geography
    ISSN: 0022-1694
    E-ISSN: 1879-2707
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  • 10
    Language: English
    In: Journal of Applied Geophysics, November 2015, Vol.122, pp.210-217
    Description: Systematic decomposition and evaluation of existing sensor systems as well as the optimal design of future generations of direct push probes are of high importance for optimized geophysical experiments since the employed equipment is a constrain on the data space. Direct push technologies became established methods in the field of geophysical, geotechnical, hydrogeological, and environmental sciences for the investigation of the near subsurface. By using direct push sensor systems it is possible to measure in-situ parameters with high vertical resolution. Such information is frequently used for quantitative geophysical model calibration of interpretation of geotechnical and hydrological subsurface conditions. Most of the available direct push sensor systems are largely based on empirical testing and consecutively evaluated under field conditions. Approaches suitable to identify specific characteristics and problems of direct push sensor systems have not been established, yet. We develop a general systematic approach for the classification, analysis, and optimization of direct push sensor systems. First, a classification is presented for different existing sensor systems. The following systematic description, which is based on the conceptual decomposition of an existing sensor system into subsystems, is a suitable way to analyze and explore the transfer behavior of the system components and therefore of the complete system. Also, this approach may serve as guideline for the synthesis and the design of new and optimized direct push sensor systems.
    Keywords: Direct Push (Dp) ; Optimized Experimental Design ; Subsurface Characterization ; Sensor System ; System Analysis ; Measurement Modeling ; Engineering
    ISSN: 0926-9851
    E-ISSN: 1879-1859
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