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  • Sage Journals (Sage Publications)  (12)
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  • 1
    Language: English
    In: PSYCHOTHERAPY AND PSYCHOSOMATICS, Vol.84, pp.20-20
    Description: BACKGROUNDKnowledge of hatha yogic exercises, the most used yoga style, for increasing functional capacity in patients with obstructive pulmonary diseases remains limited. AIMThe aim was to evaluate the effects and feasibility of hatha yoga (HY) compared to a conventional training program (CTP) on functional capacity, lung function and quality of life in patients with obstructive pulmonary diseases. DESIGNRandomized clinical trial. SETTINGThe study was performed at the Karolinska University Hospital, Stockholm, among outpatients. POPULATIONThirty-six patients with obstructive pulmonary disease. METHODSForty patients were randomized with 36 (24 women, median age =64, age range: 40-84 years) participating in HY (N.=19) or CTP (N.=17). Both HY and CTP involved a 12-week program with a 6-month follow-up. Functional capacity (using the 6-Minute Walk Test), lung function (spirometry), respiratory muscle strength (respiratory pressure meter), oxygen saturation (SpO2), breathlessness (Borg), respiratory rate (f) and disease-specific quality of life (CRQ) were measured at baseline, at 12 weeks and at a 6-month follow-up. RESULTSTesting for interactions (group x time) with ANOVAs showed significant effects on the CRQ fatigue (P=0.04) and emotional (P=0.02) domains, with improvements in the CTP group after the 12-week intervention (P=0.02 and 0.01, respectively) but not in the HY group. No between group effects emerged, however, within each group, significant improvements emerged for the six-minute walk distance (6MWD) after 12-week intervention (HY: mean difference 32.6 m; CI: 10.1-55.1, P=0.014; CTP: mean difference 42.4 m; CI: 17.9-67.0, P=0.006). SECONDARY OUTCOMESwithin-group improvements in CRQ appeared in both groups. Within the HY group, f decreased and SpO2 increased. Improved effects after follow-up emerged only for the CTP group for diastolic blood pressure (P=0.05) and CRQ emotional and fatigue domain (P=0.01). CONCLUSIONSThere were no between-group differences. After 12 weeks, 6MWD improved significantly within both groups. Within the HY group, improvements in the CRQ mastery domain, f and SpO2 emerged. Within the CTP group, there were improvements in lung function parameter forced vital capacity, respiratory muscle strength and all CRQ-domains. The CTP also exhibited effects on CRQ after the 6months follow-up. CLINICAL REHABILITATION IMPACTLimited effects of HY and CTP emerged. HY seems feasible and safe as a form of physical exercise for pulmonary disease patients. As part of the rehabilitation, HY may constitute an alternative to other physical training activities and may be a useful addition to formal rehabilitation programs.
    Keywords: Adult–Methods ; Aged–Complications ; Aged, 80 and Over–Physiopathology ; Exercise Therapy–Rehabilitation ; Exercise Tolerance–Rehabilitation ; Feasibility Studies–Rehabilitation ; Female–Rehabilitation ; Humans–Rehabilitation ; Male–Rehabilitation ; Middle Aged–Rehabilitation ; Pulmonary Disease, Chronic Obstructive–Rehabilitation ; Quality of Life–Rehabilitation ; Treatment Outcome–Rehabilitation ; Vital Capacity–Rehabilitation ; Yoga–Rehabilitation;
    ISSN: 0033-3190
    ISSN: 11184841
    E-ISSN: 19739095
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  • 2
    Language: English
    In: Journal of Learning Disabilities, July 2017, Vol.50(4), pp.422-433
    Description: Competent reading requires various skills beyond those for basic word reading (i.e., core language skills, rapid naming, phonological processing). Contributing “higher-level” or domain-general processes include information processing speed and executive functions (working memory, strategic problem solving, attentional switching). Research in this area has relied on largely Caucasian samples, with limited representation of children from racial or ethnic minority groups. This study examined contributions of executive skills to reading competence in 761 children of minority backgrounds. Hierarchical linear regressions examined unique contributions of executive functions (EF) to word reading, fluency, and comprehension. EF contributed uniquely to reading performance, over and above reading-related language skills; working memory contributed uniquely to all components of reading; while attentional switching, but not problem solving, contributed to isolated and contextual word reading and reading fluency. Problem solving uniquely predicted comprehension, suggesting that this skill may be especially important for reading comprehension in minority youth. Attentional switching may play a unique role in development of reading fluency in minority youth, perhaps as a result of the increased demand for switching between spoken versus written dialects. Findings have implications for educational and clinical practice with regard to reading instruction, remedial reading intervention, and assessment of individuals with reading difficulty.
    Keywords: Dyslexia ; Attention ; Processing Speed ; Working Memory ; Fluency ; Comprehension ; Medicine ; Education ; Psychology
    ISSN: 0022-2194
    E-ISSN: 1538-4780
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  • 3
    Language: English
    In: The American Journal of Sports Medicine, July 2002, Vol.30(4), pp.607-613
    Description: Background Internal snapping hip is an underdiagnosed cause of hip pain that sidelines many recreational and competitive athletes. It originates from a taut iliopsoas tendon that snaps across bony prominences when the hip is extended from a flexed position. When nonoperative treatment methods fail, fractional tendon-lengthening procedures may be used. Hypothesis Surgical tendon lengthening through a true ilioinguinal approach, which has not been previously reported, will achieve good results in patients with internal snapping hip. Study Design Retrospective cohort study. Methods In 30 patients with symptoms in their anterior hip, internal snapping hip was diagnosed by history and physical examination. All patients were initially treated nonoperatively; 19 (63%) improved and did not require further intervention. Eleven patients (12 hips) whose symptoms were recalcitrant to physical therapy were offered the surgical option of iliopsoas tendon lengthening. The procedure was performed via an ilioinguinal intrapelvic approach. Patients were followed up for an average of 3 years. Results All 11 surgically treated patients (100%) had complete postoperative mitigation of their snapping hip. Nine (82%) reported excellent pain relief. Moreover, nine patients thought that they had greatly benefited from the tendon lengthening and would repeat the surgery. Conclusion Although nonoperative measures are usually successful in the treatment of internal snapping hip, surgical tendon lengthening is a viable approach in cases refractory to nonoperative therapy.
    Keywords: Medicine
    ISSN: 0363-5465
    E-ISSN: 1552-3365
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  • 4
    Language: English
    In: Journal of Feline Medicine and Surgery, December 2012, Vol.14(12), pp.863-870
    Description: This study evaluated the types of items owners consider important to their cats’ quality of life (QoL). We hypothesized that items contributing to QoL in cats are predominantly items requiring mobility. The objectives of the study were to describe the types of items considered important by owners for their cats’ QoL; to describe the proportion of these items that involve mobility; to evaluate what patient factors, including severity of degenerative joint disease (DJD), affect this distribution; and to evaluate whether the proportion of QoL items involving mobility chosen by owners is different in cats presenting for a DJD study compared with a randomly selected population. A total of 830 client-generated items were evaluated. Regardless of DJD status, 40% of items listed by owners involved mobility, while 60% were ‘inactive’ items, rejecting our hypothesis. This highlights the need to assess non-active items that owners consider to constitute QoL to fully assess the impact of diseases like DJD and, therefore, the success of therapeutic interventions.
    Keywords: Veterinary Medicine
    ISSN: 1098-612X
    E-ISSN: 1532-2750
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  • 5
    Language: English
    In: Foot & Ankle Specialist, April 2013, Vol.6(2), pp.119-124
    Description: Introduction. Lawn mower injuries occur frequently in the United States and oftentimes result in extensive trauma to the lower extremities. These injuries can be quite devastating and cause there to be loss of function and amputation. The purpose of this study was to determine if there are specific factors that would help determine the best treatment protocol, patient outcomes, and prognosis after lawn mower injury to the foot and ankle. Material and Methods. A retrospective review of medical records was performed on all patients treated at a university level 1 trauma center from 2000 to 2010. Only subjects 18 years or older who sustained an injury below the level of the knee were included for review. Results. Seventy-three patients were included in this review. The results revealed that patients who developed a complication were significantly older than the group of patients without complications (P = .03). Digits were found to be injured most often but the odds of developing a complication were much higher if these injuries involved the plantar foot, dorsal foot, or ankle. Interestingly, patients on prolonged antibiotic therapy had a significantly higher risk of developing complications. The presence of comorbidities significantly increased the risk of complication (P = .008); the greatest risk factors were cardiovascular disease (P = .001) and diabetes (P = .06). Discussion. The authors present the largest cohort of lawn mower injuries in the medical literature, which demonstrates that factors such as age, location of injury, and the presence of comorbidities influence the outcome and increase the risk of injury to the foot and ankle. These results may be useful in determining the best treatment plan possible for patients with these severe injuries. Levels of Evidence: Therapeutic, Level IV, Retrospective case series
    Keywords: Complex Foot and Ankle Conditions ; General Disorders ; Trauma ; Soft-Tissue Repair ; Amputation and Limb Salvage ; Reconstructive Foot and Ankle Surgery
    ISSN: 1938-6400
    E-ISSN: 1938-7636
    Source: Sage Journals (Sage Publications)
    Source: SAGE Clinical Medicine (Sage Publications)
    Source: SAGE Health Sciences (Sage Publications)
    Source: SAGE STM (Sage Publications)
    Source: SAGE Orthopaedics and Sports Medicine (Sage Publications)
    Source: SAGE Communication and Media Studies (Sage Publications)
    Source: SAGE Journals (Sage Publications)
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  • 6
    Language: English
    In: Perfusion, July 2013, Vol.28(4), pp.306-314
    Description: Objective: The clinical benefit of normovolemic modified ultrafiltration (N-MUF) after cardiac surgery is still debated. As we have shown in a previous publication, there is a significant improvement in platelet function, so we were interested in whether ultrafiltration can reduce plasma levels of endotoxins, terminal complement complexes and cytokines after cardiopulmonary bypass (CPB) in adults with increased risk profiles. Methods: In this single-center, prospective, randomized trial, fifty high-risk patients (mean logistic EuroSCORE II: 17.5%) who underwent cardiac surgery were randomized. After CPB, Group 1 (n = 25) served as the control and in, Group 2 (n= 25), an N-MUF of 3000 ml was performed, using a BC140plus filter after weaning from CPB. Blood samples were taken after the induction of anesthesia, before CPB, before CPB weaning, 30 minutes after CPB and at 6, 24 and 48 hours postoperatively. Primary outcomes were plasma levels of lipopolysaccharide-binding protein (LBP), terminal complement complex (C5b9) and cytokines (IL-6, IL-10, IL-1beta, TNF-α). Secondary outcomes focused on differences in the clinical outcome. Results: A significant reduction in LBP concentration (preoperatively: 23.8±8.4 pg/ml, postoperatively: 14.2±12.9 pg/ml) and C5b9 (preoperatively: 4.18±2.6 pg/ml, postoperatively: 3.05±2.39 pg/ml) were detected 6 hours after N-MUF. In the N-MUF group, significantly lower concentrations of lactate could be detected in the early postoperative period. Furthermore, postoperative chest tube blood loss was significantly lower in the N-MUF group at 24 and 48 hours. Conclusions: N-MUF leads to a significant reduction of lipopolysaccharide-binding protein and terminal complement complex and was associated with reduced blood loss and postoperative lactate concentrations shortly after surgery.
    Keywords: Medicine ; Anatomy & Physiology
    ISSN: 0267-6591
    E-ISSN: 1477-111X
    Source: Sage Journals (Sage Publications)
    Source: SAGE Clinical Medicine (Sage Publications)
    Source: SAGE Health Sciences (Sage Publications)
    Source: SAGE STM (Sage Publications)
    Source: SAGE Cardiology and Cardiovascular Medicine (Sage Publications)
    Source: SAGE Communication and Media Studies (Sage Publications)
    Source: SAGE Journals (Sage Publications)
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  • 7
    Language: English
    In: Biological Research For Nursing, October 2013, Vol.15(4), pp.382-389
    Description: The CYP2D6 gene encodes for an enzyme that is involved in the metabolism of more than 25% of all medications, including many opioids and antiemetics. It may contribute to the risk of postoperative nausea and vomiting (PONV), a common surgical complication. However, little research has been conducted in this area. The purpose of this study was to explore the association of CYP2D6 genotypes with PONV in adult surgical trauma patients. Data from 112 patients (28% female) with single extremity fractures, aged 18–70 years, were analyzed. PONV was defined as present if patients reported nausea, were observed vomiting, or received medication for PONV. Saliva samples collected for DNA extraction and Taqman® allele discrimination and quantitative real time polymerase chain reaction (qRT-PCR) were used to collect genotype data that were then used to assign CYP2D6 phenotype classification. The incidence of PONV was 38% in the postanesthesia care unit and increased to 50% when assessed at 48 hr. CYP2D6 classification results were 7 (6%) poor metabolizers, 34 (30%) intermediate metabolizers, and 71 (63%) extensive metabolizers. No ultrarapid metabolizers were identified. Patients who were classified as poor metabolizers had less PONV and higher pain scores. Gender and history of PONV, but not smoking, were also significant risk factors. Findings suggest variability in CYP2D6 impacts susceptibility to PONV.
    Keywords: Cyp2d6 ; Nausea ; Vomiting ; Postoperative Symptoms ; Ponv ; Medicine ; Nursing
    ISSN: 1099-8004
    E-ISSN: 1552-4175
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  • 8
    Language: English
    In: International Journal of Stroke, June 2015, Vol.10(4), pp.589-593
    Description: Background An abnormal ankle-brachial index has been associated with overt stroke and coronary heart disease, but little is known about its relationship with silent cerebral small vessel disease. Aim To assess the value of ankle-brachial index as a predictor of silent small vessel disease in an Ecuadorian geriatric population. Methods Stroke-free Atahualpa residents aged ≥60 years were identified during a door-to-door survey. Ankle-brachial index determinations and brain magnetic resonance imaging were performed in consented persons. Ankle-brachial index ≤0·9 and ≥1·4 were proxies of peripheral artery disease and noncompressible arteries, respectively. Using logistic regression models adjusted for age, gender, and cardiovascular health status, we evaluated the association between abnormal ankle-brachial index with silent lacunar infarcts, white matter hyperintensities, and cerebral microbleeds. Results Mean age of the 224 participants was 70 ± 8 years, 60% were women, and 80% had poor cardiovascular health status. Ankle-brachial index was ≤0·90 in 37 persons and ≥1·4 in 17. Magnetic resonance imaging showed lacunar infarcts in 27 cases, moderate-to-severe white matter hyperintensities in 47, and cerebral microbleeds in 26. Adjusted models showed association of lacunar infarcts with ankle-brachial index ≤ 0·90 (OR: 3·72, 95% CI: 1·35–10·27, P = 0·01) and with ankle-brachial index ≥ 1·4 (OR: 3·85, 95% CI: 1·06–14·03, P = 0·04). White matter hyperintensities were associated with ankle-brachial index ≤ 0·90 (P= 0·03) and ankle-brachial index ≥ 1·4 (P = 0·02) in univariate analyses. There was no association between ankle-brachial index groups and cerebral microbleeds. Conclusions In this population-based study conducted in rural Ecuador, apparently healthy individuals aged ≥60 years with ankle-brachial index values ≤0·90 and ≥1·4 are almost four times more likely to have a silent lacunar infarct. Ankle-brachial index screening might allow recognition of asymptomatic people who need further investigation and preventive therapy.
    Keywords: Ankle-Brachial Index ; Cerebral Small Vessel Disease ; Peripheral Artery Disease ; Population-Based Study ; Silent Lacunar Strokes ; White Matter Hyperintensities ; Medicine
    ISSN: 1747-4930
    E-ISSN: 1747-4949
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  • 9
    Language: English
    In: Clinical Child Psychology and Psychiatry, October 2006, Vol.11(4), pp.607-617
    Description: Schulman and colleagues demonstrated that classroom activity level can be reduced in hyperactive boys using activity-level feedback and positive reinforcement. This article reports preliminary results using a device that combines modern beeper and actigraphy technology for the purpose of measuring, monitoring, and modifying motor excess in children with confirmed diagnoses of Attention Deficit Hyperactivity Disorder (ADHD). Nine boys ranging in age from 8 to 9 years with the ADHD Combined Type wore prototype BuzzBee® feedback actigraphs during school periods and were reinforced for activity-level reductions in the context of a simple pre/post research design. The findings indicated that 7 of the 9 boys reduced their activity level from 20 to 47% of baseline levels while the activity levels of the two remaining boys increased from 2 to 7% of baseline levels. These changes were statistically significant and constitute a large effect.
    Keywords: Actigraphy ; ADHD ; Biofeedback ; Positive Reinforcement ; Medicine ; Social Welfare & Social Work ; Psychology
    ISSN: 1359-1045
    E-ISSN: 1461-7021
    Source: Sage Journals (Sage Publications)
    Source: SAGE Clinical Medicine (Sage Publications)
    Source: SAGE Health Sciences (Sage Publications)
    Source: SAGE HSS (Sage Publications)
    Source: SAGE STM (Sage Publications)
    Source: SAGE Nursing and Public Health (Sage Publications)
    Source: SAGE Pediatrics (Sage Publications)
    Source: SAGE Mental Health (Sage Publications)
    Source: SAGE Psychology (Sage Publications)
    Source: SAGE Communication and Media Studies (Sage Publications)
    Source: SAGE Journals (Sage Publications)
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  • 10
    Language: English
    In: Foot & Ankle International, November 2009, Vol.30(11), pp.1042-1047
    Description: Background: An increased rate of complications has been clearly shown in diabetic patients undergoing operative treatment for displaced ankle fractures. To date, no studies have specifically looked at the complication rates following the operative management of pilon fractures in this...
    Keywords: Diabetes ; Pilon Fracture ; Plafond ; Complications
    ISSN: 1071-1007
    E-ISSN: 1944-7876
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