Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • SpringerLink Books - All  (2)
Type of Medium
Language
Year
Person/Organisation
Source
  • SpringerLink Books - All  (2)
  • 1
    Book chapter
    Book chapter
    Vienna: Springer Vienna
    Language: English
    Description: Biomarkers are any measurable and quantifiable biological parameters which serve as indices for health- or disease-related processes. The idea of identifying biological markers as indicators for an underlying disease is an elementary concept in medicine. Since the beginning of the medical skill of healing, signs and symptoms have been interpreted by medical doctors and guided diagnosis and treatment of their patients. With the emergence of the bioanalytical laboratory methods in the 50s of the last century a number of novel serum and urine markers became available. These objectively measurable serum markers were initially intended for studying physiological processes in biology. Over time, the value of such serum based biological markers for clinical decision making emerged as they were correlated with the pathology and the clinical course of disease states. This “traditional identification” of biomarkers as an observational site product of clinical practice led to the identification of the majority of clinical biomarkers employed in clinical practice today.
    Keywords: Biomedicine ; Pharmacology/Toxicology ; Pharmacy ; Pharmacy, Therapeutics, & Pharmacology
    ISBN: 9783709101438
    ISBN: 3709101433
    Source: SpringerLink Books
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Book chapter
    Book chapter
    Vienna: Springer Vienna
    Language: English
    Description: The advent of high-throughput and increasingly sensitive research techniques in molecular biology in the last 20 years has altered fundamentally our understanding of molecular biology. The unraveling of the human genome has provided unprecedented insights into the molecular pathophysiology of diseases. DNA sequencing techniques allowed collecting huge amounts of genetic information, revealing genetic variation and variable expression of genes pinpointing to the molecular level of diseases. In parallel, analytical methods for evaluating large sets of proteins become available facilitating studies on the functional relevance of transient or stable expression of these molecules for a disease phenotype. These novel molecular techniques are nowadays at the heart of modern drug research as they allow identifying and validating novel molecular targets of disease, drug screening as well as the discovery of biomarkers for predicting and monitoring response to drug therapy.
    Keywords: Biomedicine ; Pharmacology/Toxicology ; Pharmacy ; Pharmacy, Therapeutics, & Pharmacology
    ISBN: 9783709101438
    ISBN: 3709101433
    Source: SpringerLink Books
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages