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  • SwePub (National Library of Sweden)- Free access  (4)
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  • 1
    Language: English
    In: mBio, 2016-08-16, Vol.7(4)
    Description: UNLABELLED: Staphylococcus aureus is a ubiquitous opportunistic human pathogen and a major health concern worldwide, causing a wide variety of diseases from mild skin infections to systemic disease. S. aureus is a major source of severe secondary bacterial pneumonia after influenza A virus infection,...
    Keywords: Journal Article ; Medicin Och Hälsovetenskap ; Klinisk Medicin ; Infektionsmedicin ; Medical And Health Sciences ; Clinical Medicine ; Infectious Medicine
    ISSN: 2161-2129
    ISSN: 21507511
    E-ISSN: 21507511
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  • 2
    Language: English
    In: mBio, 2018-01-09, Vol.9(1)
    Description: Streptococcus pneumoniae and Staphylococcus aureus are ubiquitous upper respiratory opportunistic pathogens. Individually, these Gram-positive microbes are two of the most common causative agents of secondary bacterial pneumonia following influenza A virus infection, and they constitute a significant...
    Keywords: Streptococcus Pneumoniae ; Staphylococcus Aureus ; Biofilm ; Colonization ; Medicin Och Hälsovetenskap ; Medicinska Och Farmaceutiska Grundvetenskaper ; Mikrobiologi Inom Det Medicinska Området ; Medical And Health Sciences ; Basic Medicine ; Microbiology In The Medical Area
    ISSN: 2161-2129
    ISSN: 21507511
    E-ISSN: 21507511
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  • 3
    Language: English
    In: Nature (London), 01 November 2017, Vol.551
    Description: Our growing awareness of the importance and diversity of the microbial world contrasts starkly with our limited understanding of its fundamental structure. Despite remarkable advances in DNA sequence generation, a lack of standardized protocols and common analytical framework impede useful comparison between studies, hindering development of global inferences about microbial life on Earth. Here, we show that with coordinated protocols, exact microbial 16S rRNA gene sequences can be followed across scores of individual studies, revealing patterns of diversity, community structure, and life history strategy at a planetary scale. Using 27,751 crowdsourced environmental samples comprising more than 2.2 billion reads, we find sharp divides between host-associated and free-living communities. We show that the distribution of taxonomic and sequence diversity follows consistent trends across samples types and along gradients of environmental parameters, highlighting some of the global evolutionary patterns and ecological principles that underpin Earth’s microbiome. Here, this dataset provides the most complete environmental survey of our microbial world to date, and serves as a growing reference to provide immediate global context to future microbial surveys.
    Keywords: Environmental Sciences ; Microbiome ; Earth ; Global ; Basic Biological Sciences ; Sciences (General) ; Environmental Sciences ; Physics
    ISSN: 0028-0836
    E-ISSN: 1476-4687
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  • 4
    In: Ecology and Evolution, January 2017, Vol.7(1), pp.145-188
    Description: The project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems ()—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity. The collation of biodiversity datasets with broad taxonomic, biogeographic, and spatial extents is necessary to understand historical declines and to project—and hopefully avert—future declines. We describe and make freely available a database of more than 3.2 million biodiversity measurements from 94 countries representing over 47,000 species, collated from 480 existing spatial comparisons of local‐scale biodiversity exposed to different intensities and pressures relating to land use, from terrestrial sites around the world.
    Keywords: Data Sharing ; Global Biodiversity Modeling ; Global Change ; Habitat Destruction ; Land Use
    ISSN: 2045-7758
    E-ISSN: 2045-7758
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