Kooperativer Bibliotheksverbund

Berlin Brandenburg

X
and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Article
    Article
    A stochastic model for assessing Chlamydia trachomatis transmission risk by using longitudinal observational data (2011)
    Details
    In: Journal of the Royal Statistical Society: Series A (Statistics in Society), October 2011, Vol.174(4), pp.975-989
    Description: Bacterium causes genital chlamydia infection. Yet little is known about the efficiency of transmission of this organism. Ethical constraint against exposing healthy subjects to infected partners precludes the possibility of quantifying the risk of transmission through controlled experiments. This research proposes an alternative strategy that relies on observational data. Specifically, we present a stochastic model that treats longitudinally observed states of infection in a group of young women as a Markov process. The model proposed explicitly accommodates the parameters of transmission, including per‐encounter sexually transmitted infection acquisition risks, with and without condom protection, and the probability of antibiotic treatment failure. The male‐to‐female transmission probability of is then estimated by combining the per‐encounter disease acquisition risk and the organism's prevalence in the male partner population. The model proposed is fitted in a Bayesian computational framework.
    Keywords: Bacterial Infection ; Binary Outcome ; Longitudinal Study ; Markov Chain Monte Carlo Methods ; Markov Model ; Observational Data ; Transmission Probability
    ISSN: 0964-1998
    E-ISSN: 1467-985X
    DOI: 10.1111/j.1467-985X.2011.00691.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Article
    Open Access Request
  • 2
    Article
    Article
    Estimating transmission probabilities for chlamydial infection (1992)
    Details
    Language: English
    In: Statistics in Medicine, 1992, Vol.11(5), pp.565-577
    Description: Estimates of transmission probabilities for sexually transmitted diseases historically come from studies of uninfected individuals exposed to those with a high disease prevalence (for example, prostitutes). However, changes in sexual behaviour, much of which relates to concerns about AIDS, has made identification of populations suitable for such studies extremely difficult. This paper presents a method for estimating these probabilities that utilizes a deterministic model and routinely collected data available in many clinics. Variance estimates for the estimators are also derived. Data for chlamydial infection and sensitivity analyses for the input parameters and assumptions illustrate the method.
    Keywords: Chlamydia Trachomatis ; Models, Statistical ; Chlamydia Infections -- Transmission ; Sexually Transmitted Diseases, Bacterial -- Transmission;
    ISSN: 0277-6715
    E-ISSN: 1097-0258
    DOI: 10.1002/sim.4780110502
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Article
    Open Access Request
  • 3
    Article
    Article
    A computer enhanced runs test for smoothed data (1988)
    Details
    Language: English
    In: Statistics in Medicine, July 1988, Vol.7(7), pp.795-804
    Description: For a series of data points that follow a pattern due to natural ordering, I develop a modified runs test for continuous data to detect such a pattern. The test statistic is the number of runs in the series after having smoothed the data with use of a moving average. The testing procedure is based on permutations of the original data. My simulations indicate that the modified test is generally more powerful than the usual runs test.
    Keywords: Permutation Test ; Test For Randomness ; Simulation
    ISSN: 0277-6715
    E-ISSN: 1097-0258
    DOI: 10.1002/sim.4780070709
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Article
    Open Access Request
Nothing or not found what you are looking for? Please check your search query or use the Interlibrary Loan Search.
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages