Behavioural Brain Research, June 15, 2013, Vol.247, p.248(11)
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.bbr.2013.03.039 Byline: Vanessa Kloke, Rebecca S. Heiming, Stefanie Bolting, Sylvia Kaiser, Lars Lewejohann, Klaus-Peter Lesch, Norbert Sachser Abstract: acents Mice varying in 5-HTT expression experienced different early environments. acents Abolished 5-HTT expression reduced measures of state as well as trait anxiety. acents Early environment affected only trait but not state anxiety. acents Moderately adverse conditions lowered trait anxiety compared to social enrichment. acents Thus, anxiety profiles can be affected by the early environment and 5-HTT genotype. Author Affiliation: (a) Department of Behavioural Biology, University of Munster, Germany (b) Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Munster, Germany (c) Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Germany Article History: Received 23 January 2013; Revised 15 March 2013; Accepted 21 March 2013
Serotonin -- Genetic Aspects ; House Mouse -- Genetic Aspects ; Neurosciences -- Genetic Aspects ; Psychotherapy
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