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Berlin Brandenburg

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  • 1
    Language: English
    In: Bulletin of the Chemical Society of Japan, 12/15/2011, Vol.84(12), pp.1371-1373
    Description: Two new hydroxycembranes 1 and 2 and two known epoxycembrane 3 and isocembrol 4 have been isolated from a Formosan soft coral Sinularia facile. The structures of new metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1-4 against the proliferation of a limited panel of cancer cell lines was measured.
    Keywords: Molecular Structure ; Coral ; Metabolites ; Sinularia ; Physiology, Biochemistry, Biophysics;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 2
    Language: English
    In: Bulletin of the Chemical Society of Japan, 09/15/2012, Vol.85(9), pp.1031-1036
    Description: Chemical investigation on a Formosan octocoral identified as Briareum sp. has led to the isolation of two new 8-hydroxybriarane diterpenoids, briarenolides H (1) and I (2). The structures of briaranes 1 and 2 were established by...
    Keywords: Anions ; Derivatives ; Human ; Spectroscopy ; Miscellaneous Sciences (So) ; General and Nonclassified (MD) ; General and Nonclassified (Ep) ; General and Nonclassified (Ed) ; General and Nonclassified (EC);
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 3
    Language: English
    In: Bulletin of the Chemical Society of Japan, 08/15/2012, Vol.85(8), pp.920-922
    Description: Two new dihydrofuranocembranoids 1 and 2 with three known sarcophytonin A (3), sarcophytonin C (4), and sarcophytoxide (5) have been isolated from a Dongsha Atoll soft coral Sarcophyton sp. The structures of metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1-5 against the proliferation of a limited panel of cancer cell lines was measured.
    Keywords: Molecular Structure ; Coral ; Metabolites ; Taxonomy ; Atolls ; New Species ; Sarcophyton ; Physiology, Biochemistry, Biophysics ; Biotechnology;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 4
    Language: English
    In: Bulletin of the Chemical Society of Japan, 05/15/2011, Vol.84(5), pp.531-536
    Description: Chemical investigation on an Indonesian octocoral identified as Cladiella sp. has led to the isolation of two novel eunicellin-based diterpenoids, cladielloides C (1) and D (2). The structures of 1 and 2 were established by spectroscopic methods. Compound 1 exhibited significant cytotoxicity toward CCRF-CEM tumor cells and metabolites 1 and 2 displayed moderate inhibitory effects on superoxide anion generation by human neutrophils.
    Keywords: Chemistry;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 5
    Language: English
    In: Bulletin of the Chemical Society of Japan, 11/15/2011, Vol.84(11), pp.1237-1242
    Description: New eunicellin-based diterpenoids, klysimplexins U-X (1-4), were isolated from a cultured soft coral Klyxum simplex. Their structures were elucidated by spectroscopic methods, particularly in 1D and 2D NMR experiments. The absolute configuration of 2 was determined by Mosher's method. Compounds 1 and 2 are the first example of 4-oxygenated eunicellin-type diterpenes isolated from soft corals of this genus.
    Keywords: Molecular Structure ; Coral ; Metabolites ; Non-Edible Products ; Aquaculture;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 6
    Language: English
    In: Bulletin of the Chemical Society of Japan, 11/15/2014, Vol.87(11), pp.1278-1280
    Description: A new polybrominated indole, 4,5,6-tribromo-2-methylsulfinylindole (1), and eleven known metabolites 2-12 were isolated from the acetone extract of the red alga Laurencia brongniartii. Structure of the new compound 1 was elucidated by 1D and 2D NMR experiments. Cytotoxic, anti-inflammatory, and antibacterial activities of these sulfur-containing polybromoindoles were evaluated.
    Keywords: Cytotoxicity ; Antibacterial Activity ; Indole ; Metabolites ; N.M.R. ; Acetone ; Inflammation ; Laurencia Brongniartii ; Antibiotics & Antimicrobials ; Biochemistry;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 7
    Language: English
    In: Bulletin of the Chemical Society of Japan, 10/15/2008, Vol.81(10), pp.1304-1307
    Description: Five new polyoxygenated steroids 1-5 have been isolated from a Formosan soft coral Sinularia facile. The structures of new metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1-5 against the proliferation of a limited panel of cancer cell lines was measured. Metabolite 4 has been shown to exhibit weak cytotoxicity against Hep G2, Hep G3B, MDA-MB-231, and Ca9-22 cancer cell lines.
    Keywords: Molecular Structure ; Cytotoxicity ; Biochemistry ; Coral ; Metabolites ; Steroids ; Sinularia ; Marine ; Physiology, Biochemistry, Biophysics;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 8
    Language: English
    In: Bulletin of the Chemical Society of Japan, 11/15/2007, Vol.80(11), pp.2208-2212
    Description: Six new steroids, chabrolosteroids D-I (1-6), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of these metabolites were determined on the basis of extensive spectroscopic analysis. Metabolite 6 was found to exhibit weak cytotoxicity against the growth of Hep 3B and A-549 cell lines.
    Keywords: Molecular Structure ; Growth ; Cytotoxicity ; Coral ; Metabolites ; Steroids ; Nephthea ; Age and Growth;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 9
    Language: English
    In: Bulletin of the Chemical Society of Japan, 10/2006, Vol.79(10), pp.1547-1551
    Description: Seven new beta -caryophyllene-derived terpenoids (1-7) were isolated from EtOAc extracts of the Formosan soft coral Sinularia gibberosa. The structures of compounds 1-7 were elucidated on the basis of extensive spectroscopic analyses and by comparison with the spectral data of related metabolites. Cytotoxicity evaluation of the above metabolites towards a limited panel of cancer cell lines also will be described.
    Keywords: Molecular Structure ; Biochemistry ; Coral ; Metabolites ; Sinularia Gibberosa ; Physiology, Biochemistry, Biophysics;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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  • 10
    Language: English
    In: Bulletin of the Chemical Society of Japan, 05/2005, Vol.78(5), pp.877-879
    Description: A new eunicellin-type diterpenoid, vigulariol (1), has been isolated from the sea pen Vigularia juncea. Metabolite 1 has been obtained previously as a side product from a chemical reaction; however, it was isolated for the first time from natural resources. Also, this study established the full structure of 1 and afforded the detailed assignments of super(1)H and super(13)C NMR spectral data.
    Keywords: Molecular Structure ; Marine Invertebrates ; Chemical Reactions ; Natural Resources ; Byproducts ; Metabolites ; Vigularia Juncea ; Physiology, Biochemistry, Biophysics;
    ISSN: 0009-2673
    E-ISSN: 1348-0634
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