Language:
English
In:
Intervirology, 1997, Vol.40(5-6), pp.357-367
Description:
This review summarizes current strategies for the treatment of human cytomegalovirus (CMV) infection/diseases in high-risk patients such as transplant recipients and AIDS patients. Since the major drugs ganciclovir (Cytovene), foscarnet (Foscavir) and cidofovir (Vistide) are frequently associated with severe side effects and the formation of viral resistance, it should be endeavored to develop better strategies in anti-CMV treatment. Moreover, blocking of the viral replication does not always resolve the manifestations which are often linked with CMV-associated immunopathomechanisms. Thus, the efficacy of the available drugs is also discussed in the light of their ability to modulate inflammatory components of the cell-mediated immune system.
Keywords:
Treatment of Viral Diseases ; Human Cytomegalovirus ; Antiviral Therapy ; New Drugs ; Biology
ISBN:
9783805567251
ISBN:
3805567251
ISSN:
0300-5526
E-ISSN:
1423-0100
URL:
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