Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Language: English
    In: Microbes and Infection, 2002, Vol.4(11), pp.1141-1148
    Description: Haemophilus ducreyi is the causative agent of the genital ulcer disease chancroid. Chancroid is common in developing countries and facilitates human immunodeficiency virus transmission. In this review, the clinical features, epidemiology, and prospects for disease control are discussed in the context of experimental and natural infection of humans.
    Keywords: Haemophilus Ducreyi ; Chancroid Prevention ; Epidemiology ; Clinical Feature ; Biology
    ISSN: 1286-4579
    E-ISSN: 1769-714X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Language: English
    In: Microbes and Infection, 2006, Vol.8(9), pp.2465-2468
    Description: causes the sexually transmitted genital ulcer disease chancroid. In human inoculation experiments, bacteria colocalize with neutrophils and macrophages but remain extracellular. The organism also colocalizes with collagen and fibrin but not with keratinocytes, fibroblasts, laminin, or fibronectin. These relationships are established by 48 h postinoculation and persist through the pustular stage of disease. To extend these observations to the ulcerative stage of disease, and to compare results in the human model with those of natural disease, we obtained biopsies from patients with naturally acquired chancroid. All ulcers were culture positive for and histologically very similar to pustules from the human model. Staining with -specific monoclonal antibodies demonstrated within 5 biopsies. The organism was chiefly found within the granulocytic infiltrate of the ulcer. Dual staining for and eukaryotic tissue components showed that colocalized with neutrophils and fibrin at the ulcerative stage of disease. No bacteria were associated with keratinocytes, fibroblasts, or collagen. Overall, these findings are consistent with results from the human model. This is the first reported study to localize bacteria specifically identified as within naturally acquired chancroid.
    Keywords: Haemophilus Ducreyi ; Chancroid ; Genital Ulcer ; Bacterial Localization ; Biology
    ISSN: 1286-4579
    E-ISSN: 1769-714X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages