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Berlin Brandenburg

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  • Science  (310)
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  • 1
    Language: English
    In: Science (New York, N.Y.), 12 July 2013, Vol.341(6142), pp.128-9
    Keywords: Guidelines As Topic ; Blood Donors -- Ethics ; Reimbursement, Incentive -- Ethics
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 2
    Language: English
    In: Science (New York, N.Y.), 09 December 2016, Vol.354(6317), pp.1237-1239
    Description: Although concerns about biological weapons and terrorism were discussed by a few scientists before 2001, the broader life-sciences community was not engaged until after the 2001 anthrax-laced letters. The events of 2001 led to efforts in the United States to strengthen biological security for pathogens...
    Keywords: Security Measures ; Biohazard Release -- Prevention & Control ; Research Personnel -- Psychology
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 3
    Language: English
    In: Science (New York, N.Y.), 12 April 2013, Vol.340(6129), pp.163-5
    Description: [Index to Australopithecus sediba special section][1] The site of Malapa, South Africa, has yielded perhaps the richest assemblage of early hominin fossils on the continent of Africa. The fossil remains of Au. sediba were discovered in August of 2008, and the species was named in 2010 ([ 1 ][2])
    Keywords: Fossils ; Bone and Bones -- Anatomy & Histology ; Hominidae -- Anatomy & Histology
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 4
    Language: English
    In: Science (New York, N.Y.), 15 September 2017, Vol.357(6356), pp.1146-1149
    Description: Propagation of patterns of gene expression through the cell cycle requires prompt restoration of epigenetic marks after the twofold dilution caused by DNA replication. Here we show that the transcriptional repressive mark H3K27me3 (histone H3 lysine 27 trimethylation) is restored in replicating plant cells through DNA replication-coupled modification of histone variant H3.1. Plants evolved a mechanism for efficient K27 trimethylation on H3.1, which is essential for inheritance of the silencing memory from mother to daughter cells. We illustrate how this mechanism establishes H3K27me3-mediated silencing during the developmental transition to flowering. Our study reveals a mechanism responsible for transmission of H3K27me3 in plant cells through cell divisions, enabling H3K27me3 to function as an epigenetic mark.
    Keywords: DNA Replication ; Gene Silencing ; Histones -- Metabolism ; Plants -- Genetics
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 5
    Language: English
    In: Science (New York, N.Y.), 06 April 2007, Vol.316(5821), pp.49
    Keywords: Access to Information ; Disease Outbreaks ; Health Planning ; Periodicals As Topic ; Influenza, Human -- Epidemiology
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 6
    Language: English
    In: Science (New York, N.Y.), 09 September 2011, Vol.333(6048), pp.1411-7
    Description: Hand bones from a single individual with a clear taxonomic affiliation are scarce in the hominin fossil record, which has hampered understanding the evolution of manipulative abilities in hominins. Here we describe and analyze a nearly complete wrist and hand of an adult female [Malapa Hominin 2 (MH2)] Australopithecus sediba from Malapa, South Africa (1.977 million years ago). The hand presents a suite of Australopithecus-like features, such as a strong flexor apparatus associated with arboreal locomotion, and Homo-like features, such as a long thumb and short fingers associated with precision gripping and possibly stone tool production. Comparisons to other fossil hominins suggest that there were at least two distinct hand morphotypes around the Plio-Pleistocene transition. The MH2 fossils suggest that Au. sediba may represent a basal condition associated with early stone tool use and production.
    Keywords: Biological Evolution ; Fossils ; Hand -- Anatomy & Histology ; Hand Bones -- Anatomy & Histology ; Hominidae -- Anatomy & Histology
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 7
    Language: English
    In: Science, Jan 23, 2004, Vol.303(5657), p.483(3)
    Description: The conquest of the terrestrial environment by plants and mammals is linked to the parallel evolution of predominantly maternal control over embrogenesis and this evolution of maternal control spurred the development of an intriguing epigenetic mechanism called imprinting. Here, Berger comments on kinoshita and his colleague's proposal of a mechanism for establishing one-way control of imprinting in plants that is distinct from imprinting in mammals.
    Keywords: Gene Expression -- Chemical Properties ; Gene Expression -- Models ; Genomic Imprinting -- Research ; Genomic Imprinting -- Models
    ISSN: 0036-8075
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  • 8
    In: Conservation Biology, February 2015, Vol.29(1), pp.290-292
    Description: To purchase or authenticate to the full-text of this article, please visit this link: http://onlinelibrary.wiley.com/doi/10.1111/cobi.12327/abstract Byline: JOEL BERGER, STEVEN L. CAIN Keywords: Grand Teton National Park; policy; pronghorn; protection; Berrendo; Parque Nacional Grand Teton; politica; proteccion Abstract As the discipline of conservation biology evolves and practitioners grow increasingly concerned about how to put results into achievable conservation, it is still unclear the extent to which science drives conservation outcomes, especially across rural landscapes. We addressed this issue by examining the role of science in the protection of a biological corridor. Our focus is on a North American endemic mammal reliant on long distance migration as an adaptive strategy, the pronghorn (Antilocapra americana) of the southern Greater Yellowstone Ecosystem. The role of science in realizing policy change, while critical as a first step, was surprisingly small relative to the role of other human dimensions. In a case study, we strategically addressed a variety of conservation needs beyond science, first by building a partnership between government and private interests and then by enhancing interest in migratory phenomena across a landscape with divergent political ideologies and economic bases. By developing awareness and even people's pride in the concept of corridor conservation, we achieved local, state, and federal acceptance for protection of a 70 km long, 2 km wide pathway for the longest terrestrial migrant in the contiguous United States. Key steps included conducting and publishing research that defined the migration corridor; fostering a variety of media coverage at local, regional, and national levels; conducting public outreach through stakeholder workshops, meetings, and presentations; and meeting with and gaining the support of elected officials. All these contributed to the eventual policy change that created the first federally protected migration corridor in the United States, which in turn stimulated additional conservation actions. On the basis of our experience, we believe conservation scientists can and should step beyond traditional research roles to assist with on-the-ground conservation by engaging in aspects of conservation that involve local communities and public policy. Ir Mas Alla de la Ciencia para Proteger un Corredor Migratorio de Mamiferos Supporting information: Additional Supporting Information may be found in the online version of this article Disclaimer: Supplementary materials have been peer-reviewed but not copyedited. CAPTION(S): Methods used to construct the migration polygon and polygon shape files (Appendix S1) and GIS shapefiles for plotting the polygon are available online. The authors are solely responsible for the content and functionality of these materials. Queries (other than absence of the material) should be directed to the corresponding author.
    Keywords: Corridors (Ecology) -- Case Studies ; Ecosystems -- Case Studies;
    ISSN: 0888-8892
    ISSN: 00368075
    E-ISSN: 1523-1739
    E-ISSN: 10959203
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  • 9
    Language: English
    In: Science (New York, N.Y.), 19 June 2015, Vol.348(6241), pp.1326
    Description: Villmoare et al. (Reports, 20 March 2015, p. 1352) report on a hominin mandible from the Ledi-Geraru research area, Ethiopia, which they claim to be the earliest known representative of the genus Homo. However, certain measurements and observations for Australopithecus sediba mandibles presented are incorrect or are not included in critical aspects of the study. When correctly used, these data demonstrate that specimen LD 350-1 cannot be unequivocally assigned to the genus Homo.
    Keywords: Biological Evolution ; Hominidae -- Anatomy & Histology
    ISSN: 00368075
    E-ISSN: 1095-9203
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  • 10
    Language: English
    In: Science (New York, N.Y.), 24 February 2017, Vol.355(6327)
    Description: Cellular DNA replication factories depend on ring-shaped hexameric helicases to aid DNA synthesis by processively unzipping the parental DNA helix. Replicative helicases are loaded onto DNA by dedicated initiator, loader, and accessory proteins during the initiation of DNA replication in a tightly regulated, multistep process. We discuss here the molecular choreography of DNA replication initiation across the three domains of life, highlighting similarities and differences in the strategies used to deposit replicative helicases onto DNA and to melt the DNA helix in preparation for replisome assembly. Although initiators and loaders are phylogenetically related, the mechanisms they use for accomplishing similar tasks have diverged considerably and in an unpredictable manner.
    Keywords: DNA Replication ; Cells -- Metabolism ; DNA Helicases -- Metabolism
    ISSN: 00368075
    E-ISSN: 1095-9203
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