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1

Article

Long term exposure to cigarette smoke impacts genes involved in cardiac muscle structure and function in Apoe−/− mouse while exposure to the aerosol does not (2016)

Szostak, J ; Boué, S ; Talikka, M ; [et al.]

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Language: English

In: Toxicology Letters, 16 September 2016, Vol.258, pp.S254-S254

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2016.06.1898 Byline: J. Szostak, S. Boue, M. Talikka, E. Guedj, F. Martin, B. Phillips, N. Ivanov, M. Peitsch, J. Hoeng Author Affiliation: (1) Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland (2) Philip Morris International Research Laboratories Pte Ltd, Science Park II, Singapore

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2016.06.1898

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In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on respiratory tract tissue cultures (2013)

Kostadinova, R ; Mathis, C ; Wagner, S ; [et al.]

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Language: English

In: Toxicology Letters, 28 August 2013, Vol.221, pp.S225-S225

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2013.05.541

Source: ScienceDirect Journals (Elsevier)

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3

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Systems-toxicology approach to evaluate the biological impact of a subset of harmful/potentially harmful constituents of tobacco smoke (2013)

Gonzalez-Suarez, Ignacio ; Mathis, Carole ; Guedj, Emmanuel ; [et al.]

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Language: English

In: Toxicology Letters, 28 August 2013, Vol.221, pp.S161-S161

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2013.05.342

Source: ScienceDirect Journals (Elsevier)

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4

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Systems toxicological assessment of the mentholated Tobacco Heating System 2.2 aerosol revealed reduced cellular and molecular exposure effects compared with cigarette smoke (2016)

Kogel, U ; Titz, B ; Schlage, W.K ; [et al.]

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Language: English

In: Toxicology Letters, 10 October 2016, Vol.259, pp.S228-S228

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2016.07.547 Byline: U. Kogel, B. Titz, W.K. Schlage, C. Nury, F. Martin, A. Oviedo, S. Lebrun, A. Elamin, E. Guedj, K. Trivedi, N.V. Ivanov, P. Vanscheeuwijck, M.C. Peitsch, J. Hoeng Author Affiliation: (1) Philip Morris International R&D, Philip Morris Products S.A., Neuchatel, Switzerland (2) Philip Morris International Research Laboratories Pte. Ltd., Singapore, Singapore (3) 1 and 2 are part of Philip Morris International Group of Companies

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2016.07.547

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5

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An application of 3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product (2016)

Iskandar, A.R ; Mathis, C ; Martin, F ; [et al.]

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Language: English

In: Toxicology Letters, 10 October 2016, Vol.259, pp.S82-S83

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2016.07.202 Byline: A.R. Iskandar, C. Mathis, F. Martin, P. Leroy, A. Sewer, S. Majeed, D. Kuehn, K. Trivedi, D. Grandolfo, M. Cabanski, E. Guedj, C. Merg, S. Frentzel, N.V. Ivanov, M.C. Peitsch, J. Hoeng Author Affiliation: Philip Morris International R&D, Philip Morris Products S.A. (a member of the Philip Morris International group of companies), Quai Jeanrenaud 5, 2000 Neuchatel, Switzerland

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2016.07.202

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6

Article

Comparison of molecular changes associated with cigarette smoke-induced toxicity pathways following mice whole body and nose-only exposure (2017)

Kogel, Ulrike ; Martin, Florian ; Titz, Bjoern ; [et al.]

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Language: English

In: Toxicology Letters, 20 October 2017, Vol.280, pp.S241-S241

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2017.07.667 Byline: Ulrike Kogel (1), Florian Martin (1), Bjoern Titz (1), Gregory Vuillaume (1), Nikolai Ivanov (1), Emmanuel Guedj (1), Ashraf Elamin (1), Patrick Vanscheeuwijck (1), Julia Hoeng (1), Manuel C. Peitsch (1), K. Monica Lee (2), Michael J. Oldham (2), William Gardner (2), Willie McKinney (2) Author Affiliation: (1) Philip Morris Product SA - Research & Development (part of Philip Morris International group of companies), Neuchatel, Switzerland (2) Altria Client Services LLC, Richmond, VA, United States

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2017.07.667

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7

Article

Systems Toxicology meta-analysis: Impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on organotypic aerodigestive tract cultures (2017)

Iskandar, Anita R ; Titz, Bjoern ; Sewer, Alain ; [et al.]

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Language: English

In: Toxicology Letters, 20 October 2017, Vol.280, pp.S262-S263

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2017.07.931 Byline: Anita R. Iskandar (1), Bjoern Titz (1), Alain Sewer (1), Patrice Leroy (1), Thomas Schneider (1), Filippo Zanetti (1), Carole Mathis (1), Ashraf Elamin (1), Stefan Frentzel (1), Walter Schlage (2), Florian Martin (1), Ivanov Nikolai (1), Manuel Peitsch (1), Julia Hoeng (1)

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2017.07.931

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8

Article

Effects of exposure to e-cigarette aerosols compared with cigarette smoke on 3D human buccal and small airway cultures: a systems toxicology assessment (2018)

Iskandar, A.R ; Sandro, S ; Shoaib, M ; [et al.]

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Language: English

In: Toxicology Letters, 10 October 2018, Vol.295, pp.S80-S80

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2018.06.549

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9

Article

Toxicological assessment of the mentholated Tobacco Heating System 2.2 – A modified risk tobacco product – In a 90-day inhalation study complemented with systems toxicology (2016)

Oviedo, A ; Lebrun, S ; Ho, J ; [et al.]

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Language: English

In: Toxicology Letters, 10 October 2016, Vol.259, pp.S227-S227

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2016.07.544 Byline: A. Oviedo, S. Lebrun, J. Ho, W.T. Tan, U. Kogel, P. Leroy, B. Titz, M. Martin, C. Nury, A. Elamin, E. Guedj, N.V. Ivanov, J. Hoeng, M.C. Peitsch, P. Vanscheeuwijck Author Affiliation: (1) Philip Morris International R&D, Philip Morris Products S.A, Neuchatel, Switzerland (2) Philip Morris International Research Laboratories Pte Ltd, Science Park II, Singapore (3) 1 and 2 are part of Philip Morris International Group of Companies

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2016.07.544

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10

Article

Assessment of the Tobacco Heating System 2.2, a candidate Modified Risk Tobacco Product, on human organotypic nasal and bronchial epithelial tissue culture using systems toxicology approach (2015)

Mathis, C ; Iskandar, A ; Johne, S ; [et al.]

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Language: English

In: Toxicology Letters, 16 October 2015, Vol.238(2), pp.S323-S323

Description: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.toxlet.2015.08.920 Byline: C. Mathis, A. Iskandar, S. Johne, S. Majeed, D. Grandolfo, D. Kuehn, C. Merg, A. Elamin, E. Guedj, R. Dulize, D. Peric, K. Trivedi, A. Benyagoub, Y. Xiang, F. Martin, P. Leroy, S. Frentzel, N. Ivanov, M. Peitsch, J. Hoeng Author Affiliation: Philip Morris International, Research & Development, Neuchatel, Switzerland

Keywords: Pharmacy, Therapeutics, & Pharmacology ; Public Health

ISSN: 0378-4274

E-ISSN: 1879-3169

DOI: 10.1016/j.toxlet.2015.08.920

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