Kooperativer Bibliotheksverbund

Berlin Brandenburg


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  • 1
    Language: German
    In: BIOspektrum, 2017, Vol.23(5), pp.525-528
    Description: Single-cell RNA-seq has revolutionized our understanding of cellular heterogeneity in a wide spectrum of biological processes. Pioneering studies suggest complex mechanisms and division of labour employed by the bacterial pathogen Salmonella to subvert host cell functions during infection. Here we describe some of our findings from single-cell RNA-seq studies that have revealed and characterized heterogeneity between individual cells infected with this intracellular pathogen, and outline future challenges in this burgeoning field.
    Keywords: Life Sciences ; Life Sciences, General ; Biochemistry, General ; Human Genetics ; Microbiology ; Pharmacology/Toxicology ; Sciences (General);
    ISSN: 0947-0867
    E-ISSN: 1868-6249
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  • 2
    Language: German
    In: Angewandte Makromolekulare Chemie, June 1992, Vol.198(1), pp.135-153
    Description: Zur Charakterisierung der übermolekularen Struktur von schmelzegemischten Polybutylenterephthalat(PBT)/Polycarbonat(PC)‐Blends wurden lichtmikroskopische, rontgenographische und kalorimetrische Untersuchungen durchgeführt. Die polarisationsmikroskopischen Aufnahmen zeigen bis zu einer Konzentration von ca. 20 Gew.‐% PC eine rein sphärolithische Struktur. Bei höheren PC‐Konzentrationen wird eine zweite separate, amorphe Phase sichtbar. Mit der DSC‐Methode wurde eine Verschiebung der Glasübergangstemperatur beider Ausgangskomponenten, eine geringe Schmelzpunkterniedrigung der kristallinen PBT‐Phase und unterschiedliche Kristallisationstemperaturen in Abhängigkeit von der Konzentration der Ausgangskomponenten gemessen. Eine Erniedrigung des Kristallinitätsgrades des PBT und eine Kristallisation des PC, insbesondere bei thermischer Nachbehandlung der Blends, wurde mittels Röntgenbeugung und ergänzender Dichtemessungen nachgewiesen. Light‐microscopic, X‐ray and calorimetric investigations were carried out to characterize the morphology of melt‐mixed poly(butylene terephthalate)(PBT)/polycarbonate(PC)‐blends. A completely spherulitic structure up to a concentration of about 20 wt.‐% PC was found by polarizing microscopy. A second separate, amorphous phase appears at higher PC concentrations. By differential scanning calorimetry, a shift of the glass transition temperature of PBT as well as PC, a slight melting point depression of the crystalline PBT‐phase and different crystallization temperatures depending on the concentration of the pure components were measured. Wide‐angle X‐ray studies and additional density measurements gave reason to believe that the crystallinity of PBT in the blend is decreasing and that there is a possibility of crystallization of PC, particularly by a thermal post‐treatment.
    ISSN: 0003-3146
    E-ISSN: 1522-9505
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