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  • Japanese  (36)
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  • 1
    Language: Japanese
    In: 日本温泉気候物理医学会雑誌, 1990-05, Vol.53(3), pp.p159~172
    Description: 記事分類: 医学--治療医学
    Description: Title Transcription: General Physiological Principles of Bal
    Description: Material Type: 記事・論文
    Keywords: Balneotherapy ; General ; Physiological ; Principles ; Spa ; Treatment;
    ISSN: 00290343
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  • 2
    Language: English
    In: Annals of the Institute of Statistical Mathematics, 2016, Vol.68(4), pp.827-853
    Description: We consider the problem of estimating an additive regression function in an inverse regression model with a convolution type operator. A smooth backfitting procedure is developed and asymptotic normality of the resulting estimator is established. Compared to other methods for the estimation in additive models the new approach neither requires observations on a regular grid nor the estimation of the joint density of the predictor. It is also demonstrated by means of a simulation study that the backfitting estimator outperforms the marginal integration method at least by a factor of two with respect to the integrated mean squared error criterion. The methodology is illustrated by a problem of live cell imaging in fluorescence microscopy.
    Keywords: Inverse regression ; Additive models ; Curse of dimensionality ; Smooth backfitting
    ISSN: 0020-3157
    E-ISSN: 1572-9052
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  • 3
    Language: English
    In: The Journal of reproduction and development, 13 April 2018, Vol.64(2), pp.187-191
    Description: Here we report in vitro and term development of sheep embryos after the inner cell mass (ICM) from one set of sheep blastocysts were injected into the trophoblast vesicles of another set. We also observed successful in vitro development of chimeric blastocysts made from sheep trophoblast vesicles injected with bovine ICM. First, we dissected ICMs from 35 sheep blastocysts using a stainless steel microblade and injected them into 29 re-expanded sheep trophoblastic vesicles. Of the 25 successfully micromanipulated trophoblastic vesicles, 15 (51.7%) re-expanded normally and showed proper ICM integration. The seven most well reconstructed embryos were transferred for development to term. Three ewes receiving manipulated blastocysts were pregnant at day 45 (42.8%), and all delivered normal offspring (singletons, two females and one male, average weight: 3.54 ± 0.358 kg). Next, we monitored in vitro development of sheep trophoblasts injected with bovine ICMs. Of 17 injected trophoblastic vesicles, 10 (58.8%) re-expanded after 4 h in culture, and four (40%) exhibited integrated bovine ICM. Our results indicate that ICM/trophoblast exchange is feasible, allowing full term development with satisfactory lambing rate. Therefore, ICM exchange is a promising approach for endangered species conservation.
    Keywords: Blastocysts ; Bovine ; In Vitro Fertilization ; Inner Cell Mass Exchange ; Sheep ; Ectogenesis ; Fetal Development ; Blastocyst Inner Cell Mass -- Cytology ; Cloning, Organism -- Veterinary ; Embryo Transfer -- Veterinary ; Trophoblasts -- Cytology
    ISSN: 09168818
    E-ISSN: 1348-4400
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  • 4
    Language: Japanese
    In: 日本野生動物医学会誌, 2012, Vol.17(3), pp.97-109
    Description: 〈p〉 近年,ゾウは,飼育下での低い繁殖成功率や,野生からの新たな個体導入の停止により生息数が減少している。一方,ホルモン測定や超音波検査の発展,アフリカでの生息数調整などから得られた研究成果は,現在のゾウの生殖周期に関する知識の発展に貢献してきた。ゾウの繁殖特性は他の哺乳類と明らかに異なっており,泌尿生殖器の解剖学的構造,発情周期の長さや構成,副黄体の形成,生殖ホルモンの分泌パターンなどが特徴的である。雌ゾウの発情周期は12~18週であり,現在までに知られている周年繁殖動物の中で最長である。プロゲステロンが排卵後1~3日で上昇して黄体期が始まり,6~12週続く。その後4~6週間ある卵胞期の終わりには,正確に時間差のある2回のLHサージが起こる。一般的に,1回目のLHサージは排卵を誘起せず,その19~21日後の2回目のLHサージで排卵が誘起され,通常,1個の卵胞が排卵する。しかし,排卵部位での黄体形成に加えて,卵巣には複数の黄体が観察される。他の多くの動物種と違い,黄体組織から分泌される主なプロゲスタジェンはプロゲステロンではなく,プロゲステロンから5α減少した代謝物である。今回,アジアゾウ,アフリカゾウで現在分かっているユニークな発情周期について,発情行動,生殖関連ホルモン,生殖器官の超音波と形態学的構造,病理学的面を,ホルモン処置の可能性も含めて説明した。〈/p〉
    Description: 〈p〉The combination of a few factors, including poor captive reproduction, secession of importation from the wild, advances in hormone detection and ultrasonography, and, regrettably, elephant culling in Africa, has contributed to the current knowledge on the elephant cycle. Several reproductive features in elephants differ markedly from other mammals. These include the urogenital tract anatomy, length and structure of the cycle, the formation of multiple corpora lutea and the type and secretion pattern of reproductive hormones. Being 12 to 18 weeks in length, the elephant estrous cycle is the longest amongst all studied non-seasonal mammals to date. Progesterone rises one to three days after ovulation, indicating the start of the luteal phase, which lasts six to 12 weeks. This is followed by a four to six weeks follicular phase that is concluded by two, precisely spaced and timed, LH surges. In general, the first, anovulatory LH surge occurs exactly 19 to 21 days before the second, ovulatory surge. Normally, a single follicle is ovulated. However, beside a corpus luteum (CL) forming on the site of ovulation, multiple accessory CLs can be found on the ovaries. Unlike many other species, the predominant progestagen secreted by luteal tissues is not progesterone, but rather its 5-α-reduced metabolites. The currently known aspects of the unique estrous cycle in Asian and African elephants, covering estrous behavior, circulating hormones, ultrasonography and anatomy of the reproductive organs and its pathology as well as hormonal manipulation treatment possibilities, will be reviewed here.〈/p〉
    Keywords: 雌ゾウ ; 発情周期 ; 黄体化卵胞 ; 卵胞発育 ; 副黄体 ; Female Elephant ; Estrous Cycle ; Hormonal Pattern ; Follicular Development ; Accessory Corpora Lutea
    ISSN: 1342-6133
    Source: Japan Science and Technology Agency
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  • 5
    Language: English
    In: Japanese Journal of Zoo and Wildlife Medicine, 2012, Vol.17(3), pp.97-109
    Description: The combination of a few factors, including poor captive reproduction, secession of importation from the wild, advances in hormone detection and ultrasonography, and, regrettably, elephant culling in Africa, has contributed to the current knowledge on the elephant cycle. Several reproductive features in elephants differ markedly from other mammals. These include the urogenital tract anatomy, length and structure of the cycle, the formation of multiple corpora lutea and the type and secretion pattern of reproductive hormones. Being 12 to 18 weeks in length, the elephant estrous cycle is the longest amongst all studied non-seasonal mammals to date. Progesterone rises one to three days after ovulation, indicating the start of the luteal phase, which lasts six to 12 weeks. This is followed by a four to six weeks follicular phase that is concluded by two, precisely spaced and timed, LH surges. In general, the first, anovulatory LH surge occurs exactly 19 to 21 days before the second, ovulatory surge. Normally, a single follicle is ovulated. However, beside a corpus luteum (CL) forming on the site of ovulation, multiple accessory CLs can be found on the ovaries. Unlike many other species, the predominant progestagen secreted by luteal tissues is not progesterone, but rather its 5-α-reduced metabolites. The currently known aspects of the unique estrous cycle in Asian and African elephants, covering estrous behavior, circulating hormones, ultrasonography and anatomy of the reproductive organs and its pathology as well as hormonal manipulation treatment possibilities, will be reviewed here.
    ISSN: 1342-6133
    E-ISSN: 2185-744X
    Source: CrossRef
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  • 6
    Language: English
    In: Physical Review B, 12/2002, Vol.66(24)
    Description: Taking account of exchange-correlation (XC) effects, we investigate two-dimensional (2D) plasmons (PL’s) in a metallic monolayer on a semiconductor surface. The energy dispersion and the energy-loss intensity of the 2D PL are calculated in close relation to a recent experiment by high-resolution electron energy-loss spectroscopy. We evaluate the XC effects by using the local-field-correction theory and by comparing the calculated results among (i) the random-phase approximation, (ii) the Hartree-Fock approximation, and (iii) the approximation originally formulated by Singwi, Tosi, Land, and Sjölander. We determine the electron density n0 and the electron effective mass m* so that the results in (iii) accord with the experimental ones. Our calculations give a good description of the energy dispersion and the energy-loss intensity of the 2D PL and the PL decay due to single-particle excitations in the experiment. With an increase in wave number q, the exchange and correlation begin to lower the dispersion curve and make the 2D PL decay at a smaller q value. Our electron system has a high effective density, because it lies on a semi-infinite dielectric medium. However, owing to low dimensionality, the XC effects start to appear remarkably in the 2D PL with an increase in q.
    Keywords: Physics;
    ISSN: 0163-1829
    E-ISSN: 1095-3795
    Source: American Physical Society (APS) (via CrossRef)
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  • 7
    Language: Japanese
    In: 日本温泉気候物理医学会雑誌, 1980-11, Vol.44(1・2), pp.p1~37
    Description: Title Transcription: Chronobiological Aspects of Cure Treatm
    Description: Material Type: 記事・論文
    Keywords: 45回 ; Aspects ; Chronobiologica ; Cure ; Treatment ; 医学会 ; 温泉 ; 気候 ; 総会 ; 第 ; 日本 ; 物理;
    ISSN: 00290343
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  • 8
    Language: Japanese
    In: Review of gastroenterology & clinical gastroenterology and hepatology, 2010-05, Vol.5(1), pp.21~24
    Description: 記事種別: 翻訳
    Description: Title Transcription: Alimentary Tract コウシボウショク ワ ヒマン ノ ウム ニ カンケイ ナク マウス チョウ ナイ サイキンソウマイクロバイオーム ノ コウセイ オ ケッテイ スル
    Description: Alternative Title: High-fat diet determines the composition of the murine gut microbiome independently of obesity
    Description: Material Type: 記事・論文
    Keywords: メタゲノム解析 ; 腸内細菌叢 ; マイクロバイオーム
    ISSN: 1881073X
    Source: Zassaku –(Japanese Periodicals Index) (National Diet Library of Japan)
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  • 9
    Language: English
    In: The Journal of reproduction and development, 2012, Vol.58(1), pp.105-11
    Description: The objective of the present study was to define the secretion of prolactin (PRL) in pregnant African and Asian elephants. Levels of immunoreactive (ir-) PRL in serum and placental homogenates were measured by a heterologous radioimmunoassay (RIA) based on an ovine and human RIA system, and the localization of ir-PRL in the placenta was detected by immunohistochemistry using anti-human PRL. Circulating ir-PRL clearly showed a biphasic pattern during pregnancy in African and Asian elephants. Serum levels of ir-PRL started to increase from the 4 - 6th month of gestation and reached the first peak level around the 11-14th month. A second peak of circulating ir-PRL levels was observed around the 18-20th month of gestation followed by an abrupt decline after parturition. In contrast, in a case of abortion of an African elephant, the second peak of ir-PRL was not observed, and the levels remained low for about four months until parturition. The weight of the fetus delivered at the 17th month of gestation was 23.5 kg, which was quite small compared with normal fetuses in previous reports. Ir-PRL was detected in placental homogenates, and immunolocalization was observed in trophoblasts in both the African and Asian elephants, indicating that the placenta is the source of ir-PRL during pregnancy in elephants. The present results clearly demonstrated that circulating ir-PRL shows a biphasic pattern during normal pregnancy and that the placenta appears to be an important source of circulating ir-PRL during pregnancy in both African and Asian elephants.
    Keywords: Elephants -- Blood ; Pregnancy, Animal -- Blood ; Prolactin -- Blood
    ISSN: 09168818
    E-ISSN: 1348-4400
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  • 10
    Language: Japanese
    In: 日本温泉気候物理医学会雑誌, 1993-11, Vol.57(1), pp.p9~10
    Description: Material Type: 記事・論文
    Keywords: 58回 ; 医学 ; 医学会 ; 医学的 ; 温泉 ; 気候 ; 現代 ; 講演 ; 総会 ; 第 ; 特別 ; 独文 ; 日本 ; 物理 ; 保養地;
    ISSN: 00290343
    Source: Zassaku –(Japanese Periodicals Index) (National Diet Library of Japan)
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