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  • 1
    UID:
    b3kat_BV010790981
    Format: III, 174 S. , Ill., graph. Darst.
    Note: Göttingen, Univ., Diss., 1995
    Language: German
    Keywords: Douglasienholz ; Furnier ; Rauigkeit ; Hochschulschrift
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  • 2
    Online Resource
    Online Resource
    Cham : Springer
    UID:
    b3kat_BV047226753
    Format: 1 Online-Ressource (xi, 352 Seiten) , Illustrationen
    ISBN: 9783030631642
    Series Statement: Cardiac and vascular biology volume 8
    Additional Edition: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 978-3-030-63163-5
    Additional Edition: Erscheint auch als Druck-Ausgabe, Paperback ISBN 978-3-030-63166-6
    Language: English
    Keywords: Aufsatzsammlung
    URL: Volltext  (URL des Erstveröffentlichers)
    Author information: Hecker, Markus 1960-
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  • 3
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Springer
    UID:
    b3kat_BV048918788
    Format: 1 Online-Ressource (VIII, 353 p. 1 illus)
    Edition: 1st ed. 2023
    ISBN: 9783031239656
    Series Statement: Cardiac and Vascular Biology 9
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-23964-9
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-23966-3
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-031-23967-0
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 4
    UID:
    gbv_1747663204
    Format: 1 Online-Ressource (89 p.)
    Series Statement: OECD Series on Adverse Outcome Pathways no.12
    Content: This AOP details the linkage between activation of the aryl hydrocarbon receptor (AhR) and early life stage mortality in oviparous vertebrates. It can be initiated mostly by dioxin-like compounds, which are able to bind to the AhR causing heterodimerisation with the aryl hydrocarbon nuclear translocator (ARNT) and interaction with dioxin-responsive elements on the DNA causing an up-regulation in dioxin responsive genes. One dioxin-responsive gene is cyclooxygenase 2 (COX-2), which has roles in development of the cardiovascular system. Up-regulation in expression of COX-2 causes alteration in cardiovascular development and function resulting in reduced heart pumping efficiency, reduced blood flow, and eventual cardiac collapse and death. Comparable apical manifestations of activation of the AhR have been recorded across freshwater and marine teleost and non-teleost fishes, as well as birds. Despite conservation in the AOP across taxa, great differences in sensitivity to perturbation exist both among and within taxonomic groups.
    Language: English
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  • 5
    UID:
    b3kat_BV047932439
    Format: 1 Online-Ressource (89 Seiten)
    Series Statement: OECD Series on Adverse Outcome Pathways
    Content: This AOP details the linkage between activation of the aryl hydrocarbon receptor (AhR) and early life stage mortality in oviparous vertebrates. It can be initiated mostly by dioxin-like compounds, which are able to bind to the AhR causing heterodimerisation with the aryl hydrocarbon nuclear translocator (ARNT) and interaction with dioxin-responsive elements on the DNA causing an up-regulation in dioxin responsive genes. One dioxin-responsive gene is cyclooxygenase 2 (COX-2), which has roles in development of the cardiovascular system. Up-regulation in expression of COX-2 causes alteration in cardiovascular development and function resulting in reduced heart pumping efficiency, reduced blood flow, and eventual cardiac collapse and death. Comparable apical manifestations of activation of the AhR have been recorded across freshwater and marine teleost and non-teleost fishes, as well as birds. Despite conservation in the AOP across taxa, great differences in sensitivity to perturbation exist both among and within taxonomic groups
    Language: English
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 6
    Online Resource
    Online Resource
    Cham : Springer International Publishing | Cham : Imprint: Springer
    UID:
    gbv_1753058953
    Format: 1 Online-Ressource(XI, 352 p. 49 illus., 40 illus. in color.)
    Edition: 1st ed. 2021.
    ISBN: 9783030631642
    Series Statement: Cardiac and Vascular Biology 8
    Content: Preface -- Hemodynamics and vascular remodeling -- The biomechanics of venous remodeling -- New kids on the block: the emerging role of YAP/TAZ in vascular cell mechano-transduction -- GPCRs und flow and pressure -- Biomechanics in small artery remodeling -- Contributions of wall stretch and shear stress to vascular regulation: Molecular mechanisms of homeostasis and expansion -- Mechanobiology of lymphatic vessels -- Hemodynamic control of endothelial cell fates in development -- Mechanical regulation of epigenetic modifications in vascular biology and pathobiology -- Mechanosensing and mechanotransduction in pulmonary hypertension -- Mechanobiology of arterial hypertension -- Mechanobiology of atherosclerosis -- Exploitation of vascular mechanobiology for cardiovascular therapy.
    Content: This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiacmechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
    Additional Edition: ISBN 9783030631635
    Additional Edition: ISBN 9783030631659
    Additional Edition: ISBN 9783030631666
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783030631635
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783030631659
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783030631666
    Language: English
    Keywords: Gefäßsystem ; Gefäßkrankheit ; Biomechanik
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  • 7
    UID:
    b3kat_BV026325609
    Format: 144 S. , graph. Darst.
    ISBN: 3891911653
    Series Statement: Konstanzer Dissertationen 198
    Note: Zugl.: Konstanz, Univ., Diss., 1987
    Language: German
    Keywords: Thromboxane ; Biosynthese ; Prostaglandin H2 ; Biosynthese ; Thromboxan A2 ; Biosynthese ; Prostacyclin ; Biosynthese ; Hochschulschrift
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  • 8
    UID:
    gbv_1044403705
    Format: graph. Darst.
    ISSN: 0932-9315
    In: Forst und Holz, Hannover : Schlüter, 1946, Jg. 60.2005, S. 250 - 252, 0932-9315
    In: volume:60
    In: year:2005
    In: pages:250-252
    Language: Undetermined
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