Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Monograph/Item  (97)
  • English  (97)
Type of Material
Type of Publication
  • Monograph/Item  (97)
Consortium
Language
  • English  (97)
  • 1
    UID:
    (DE-627)658543822
    Format: Online Ressource (3031 KB, 222 S.)
    Edition: 1. Aufl.
    Edition: Online-Ausg. 2011 Electronic reproduction; Available via World Wide Web
    ISBN: 3805576188 , 9783805576185
    Series Statement: Monographs in virology v. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell. This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed. The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002.
    Note: Includes bibliographical references and index , ""Contents""; ""Preface""; ""The Endothelium as a Mediator of CMV-Associated Immunopathology""; ""Effect of CMV Infection on Chronic Rejection of Kidney Transplants""; ""CMV and Atherosclerosis""; ""Human Cytomegalovirus in Immune Privileged Sites: HCMV Retinitis and the Role of NF-kB""; ""Transmission of Cytomegalovirus to Preterm Infants by Breast-Feeding""; ""Human Cytomegalovirus Escapes Cell-Mediated Immune Responses""; ""Counteraction of Interferon-Induced Antiviral Responses by Cytomegalovirus""; ""Mechanisms of Immunodominance in Human Cytomegalovirus Infection"" , ""HCMV Latency and Lytic Gene Regulation: A Question of Chromatin Structure?""""Taking Away the Replication License � HCMV and Its Impact on Cellular DNA Synthesis""; ""Interactions and Functions of Human Cytomegalovirus Tegument Proteins""; ""Measuring T-Cell Reactivity to Cytomegalovirus: State of the Art""; ""Measurement of CMV DNA Levels and CMV-Specific CD4 + Lymphocyte Counts in Patient Specimens: Requirements for Test Quality and Practicability in a Routine Diagnostic Service""; ""Manipulation of CMV-Specific Immune Responses following Stem Cell Transplantation"" , ""Fast Genotypic Identification and Estimation of Ganciclovir-Resistant Cytomegalovirus from Clinical Specimens""""Non-Nucleoside Inhibitors of HCMV Replication""; ""New Concepts for Inhibition of HCMV Reactivation and Replication""; ""CMV Vaccines to Prevent Congenital Infection""; ""Subject Index"" , Electronic reproduction; Available via World Wide Web
    Additional Edition: Print version New Aspects of CMV-Related Immunopathology : 4th Symposium, Berlin, September 2002
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    UID:
    (DE-604)BV036069276
    Format: 1 Online-Ressource (X, 212 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318010060
    Series Statement: Monographs in virology Vol. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell.This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed.The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs
    Note: 4th Symposium, Berlin, September 2002
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7618-5
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Cytomegalie ; Infektion ; Immunpathologie ; Konferenzschrift
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    UID:
    (DE-602)b3kat_BV036069276
    Format: 1 Online-Ressource (X, 212 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318010060
    Series Statement: Monographs in virology Vol. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell.This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed.The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs
    Note: 4th Symposium, Berlin, September 2002
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7618-5
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Cytomegalie ; Infektion ; Immunpathologie ; Konferenzschrift
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    UID:
    (DE-602)b3kat_BV036069354
    Format: 1 Online-Ressource (VIII, 164 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318006223
    Series Statement: Contributions to microbiology Vol. 7
    Content: In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7124-1
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Spongiöse subakute Encephalopathie ; Prion ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung
    URL: Volltext  (Deutschlandweit zugänglich)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    UID:
    (DE-604)BV036069354
    Format: 1 Online-Ressource (VIII, 164 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318006223
    Series Statement: Contributions to microbiology Vol. 7
    Content: In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7124-1
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Spongiöse subakute Encephalopathie ; Prion ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    UID:
    (DE-602)b3kat_BV036069355
    Format: 1 Online-Ressource (XI, 221 Seiten) , Illustrationen, Diagramme
    Edition: 2nd, revised and extended edition
    ISBN: 9783318010329
    Series Statement: Contributions to microbiology Vol. 11
    Content: This second, completely revised and extended edition of 〈i〉Prions: A Challenge for Science, Medicine and the Public Health System〈/i〉 is a comprehensive, up-to-date review of prions and prion-associated diseases. Leading scientists discuss the structure, molecular biology and origin of prions as well as strain variations and species barriers. Human prion diseases, prion inactivation and risks to public health are considered in detail. The new edition provides an update on basic findings of the last three years since publication of the previous edition and emphasizes practical aspects of fighting human and animal prion diseases. In addition, chapters on regulatory aspects of BSE and CJD as well as on veterinary measures have been included.A valuable single source of information on what is currently known about prions, this book will be of interest to any scientist or clinician who wants to keep up with the latest developments in this fast-moving field
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7656-7
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Prion ; Spongiöse subakute Encephalopathie ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung
    URL: Volltext  (Deutschlandweit zugänglich)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    UID:
    (DE-627)32118999X
    Format: VIII, 164 S. , Ill., graph. Darst. , 25 cm
    ISBN: 3805571240
    Series Statement: Contributions to microbiology 7
    Note: Includes bibliographical references and indexes
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Prion ; Spongiöse subakute Encephalopathie ; Jakob-Creutzfeldt-Syndrom ; Prion ; Spongiöse subakute Encephalopathie ; Jakob-Creutzfeldt-Syndrom ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    UID:
    (DE-604)BV036069355
    Format: 1 Online-Ressource (XI, 221 Seiten) , Illustrationen, Diagramme
    Edition: 2nd, revised and extended edition
    ISBN: 9783318010329
    Series Statement: Contributions to microbiology Vol. 11
    Content: This second, completely revised and extended edition of 〈i〉Prions: A Challenge for Science, Medicine and the Public Health System〈/i〉 is a comprehensive, up-to-date review of prions and prion-associated diseases. Leading scientists discuss the structure, molecular biology and origin of prions as well as strain variations and species barriers. Human prion diseases, prion inactivation and risks to public health are considered in detail. The new edition provides an update on basic findings of the last three years since publication of the previous edition and emphasizes practical aspects of fighting human and animal prion diseases. In addition, chapters on regulatory aspects of BSE and CJD as well as on veterinary measures have been included.A valuable single source of information on what is currently known about prions, this book will be of interest to any scientist or clinician who wants to keep up with the latest developments in this fast-moving field
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7656-7
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Prion ; Spongiöse subakute Encephalopathie ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Online Resource
    Online Resource
    Basingstoke : Stockton Press | Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg
    UID:
    (DE-603)51428157X
    Format: 1 Online-Ressource (9 Seiten)
    Content: Although human cytomegalovirus (HCMV) is generally not regarded to be an oncogenic virus, HCMV infection has been implicated in malignant diseases from different cancer entities. On the basis of our experimental findings, we developed the concept of “oncomodulation” to better explain the role of HCMV in cancer. Oncomodulation means that HCMV infects tumor cells and increases their malignancy. By this concept, HCMV was proposed to be a therapeutic target in a fraction of cancer patients. However, the clinical relevance of HCMV-induced oncomodulation remains to be clarified. One central question that has to be definitively answered is if HCMV establishes persistent virus replication in tumor cells or not. In our eyes, recent clinical findings from different groups in glioblastoma patients and especially the detection of a correlation between the numbers of HCMV-infected glioblastoma cells and tumor stage (malignancy) strongly increase the evidence that HCMV may exert oncomodulatory effects. Here, we summarize the currently available knowledge about the molecular mechanisms that may contribute to oncomodulation by HCMV as well as the clinical findings that suggest that a fraction of tumors from different entities is indeed infected with HCMV.
    Additional Information: Enthalten in Neoplasia. Jahrgang 11, Heft 1
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    UID:
    (DE-627)1805909223
    Format: 1 Online-Ressource (viii, 164 pages) , illustrations
    ISBN: 0585440565 , 9780585440569
    Series Statement: Contributions to microbiology vol. 7
    Content: In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection
    Note: Includes bibliographical references and indexes
    Additional Edition: 9783318006223
    Additional Edition: 331800622X
    Additional Edition: 3805571240
    Additional Edition: Erscheint auch als Druck-Ausgabe Prions Basel ; New York : Karger, ©2001
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages