Format:
Online-Ressource
ISSN:
1867-3899
Content:
Abstract: We report the synthesis of nine new N‐heterocyclic carbene gold bifluoride complexes starting from the corresponding N‐heterocyclic carbene gold hydroxides. A new methodology to access N,N′‐bis (2,6‐diisopropylphenyl) imidazol‐2‐ylidene gold (I) fluoride starting from N,N′‐bis (2,6‐diisopropylphenyl) imidazol‐2‐ylidene gold (I) hydroxide and readily available potassium bifluoride is also reported. These gold bifluorides were shown to be efficient catalysts in the hydrofluorination of symmetrical and unsymmetrical alkynes, thus affording fluorinated stilbene analogues and fluorovinyl thioethers in good to excellent yields with high stereo‐ and regioselectivity. The method is exploited further to access a fluorinated combretastatin analogue selectively in two steps starting from commercially available reagents.
In:
volume:7
In:
number:2
In:
year:2015
In:
pages:240-244
In:
extent:5
In:
ChemCatChem, Weinheim : Wiley-VCH, 2009-, 7, Heft 2 (2015), 240-244 (gesamt 5), 1867-3899
Language:
English
DOI:
10.1002/cctc.201402891
URN:
urn:nbn:de:101:1-2022122305022504070198
URL:
https://doi.org/10.1002/cctc.201402891
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2022122305022504070198
URL:
https://d-nb.info/127642258X/34
URL:
https://doi.org/10.1002/cctc.201402891
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