Format:
1 Online-Ressource (xvi, 304 pages)
,
digital, PDF file(s)
ISBN:
9780511546266
Series Statement:
Advances in molecular and cellular microbiology 2
Content:
Our survival as multicellular organisms requires the constant surveillance of our internal and external (mucosal) environments by the multifarious elements of the innate and acquired systems of immunity. The objective of this surveillance, expensive as it is to the organisms, is to recognise and kill invading microorganisms. Over the past fifty years the cells and mediators involved in our immune defences have been painstakingly identified. However, it is only relatively recently that the ability of microorganisms to evade immunity has been recognised and investigated. Bacterial Evasion of Host Immune Responses introduces the reader to the mechanisms used by bacteria to evade both humoral and cellular immune responses, using systems ranging in complexity from the simple quorum sensing molecules - acyl homoserine lactones - to the supramolecular syringe-like devices of type III secretion systems. This book will be of interest to researchers and graduate students in microbiology, immunology, pharmacology and molecular medicine
Content:
Part I. Recognition of bacteria: [Ch.] 1. The dendritic cell in bacterial infection : sentinel or Trojan horse? / Benjamin M. Chain and Janusz Marcinkiewicz -- [ch.] 2. CD1 and nonpeptide antigen recognition systems in microbial immunity / Kayvan R. Niazi, Steven A. Pocelli, and Robert L. Modlin -- [ch.] 3. The NRAMP family : co-evolution of a host/pathogen defence system -- Part II. Evasion of humoral immunity: [ch.] 4. Evasion of complement system pathwas by bacteria / Michael A. Kerr and Brian Henderson -- [ch.] 5. Bacterial immunoglobulin-evading mechanisms : lg-dregrading and lg-binding proteins / Mogen Kilian -- [ch.] 6. Evasion of antibody responses : bacterial phase variation / Nigel J. Saunders -- Part III. Evasion of cellular immunity: [ch.] 7. Type III protein secretion and resistance to phagocytosis / Ake Forsberg, Roland Rosqvist and Maria Fallman -- [ch.] 8. Bacterial superantigens and immune evasion / John Fraser, Thomas Proft, Vickery Arcus and Edward Baker -- [ch.] 9. Bacterial quorum sensing signalling molecules as immune modulators / David Pritchard, Doreen Hooi, Eleanor Watson, Sek Chow, Gary Telford, Barrie Bycroft, Siri Ram Chhabra, Christopher Harty, Miguel Camara, Stephen Diggle and Paul Williams -- [ch.] 10. Microbial modulation of cytokine networks / B. Henderson and Rob M. Seymour -- [ch.] 11. Enterotoxins : adjuvants and immune inhibitors / Jan-Michael Klapproth and Michael S. Donnenberg -- [ch.]. 12. Type III protein secretion and inhibition of NF-kB / Klaus Ruckdeschel, Bruno Rouot and Jü̈rgen Heesemann
Note:
Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Additional Edition:
ISBN 9780521801737
Additional Edition:
Print version ISBN 9780521801737
Language:
English
DOI:
10.1017/CBO9780511546266
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