Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (ix, 156 pages) : , digital, PDF file(s).

ISBN: 9780511842382 (ebook)

Content: How do we understand and explain the apparent dichotomy between plasticity and robustness in the context of development? Can we identify these complex processes without resorting to 'either/or' solutions? Written by two leaders in the field, this is the first book to fully unravel the complexity of the subject, explaining that the epigenetic processes generating plasticity and robustness are in fact deeply intertwined. It identifies the different mechanisms that generate robustness and the various forms of plasticity, before considering the functional significance of the integrated mechanisms and how the component processes might have evolved. Finally, it highlights the ways in which epigenetic mechanisms could be instrumental in driving evolutionary change. Essential reading for biologists and psychologists interested in epigenetics and evolution, this book is also a valuable resource for biological anthropologists, sociobiologists, child psychologists and paediatricians.

Note: Title from publisher's bibliographic system (viewed on 05 Oct 2015). , 1. Setting the scene -- 2. Clarifications -- 3. Developmental robustness -- 4. Plasticity -- 5. Integration of robustness and plasticity -- 6. Current functions of integrated developmental processes -- 7. Evolution of developmental processes -- 8. Impact of developmental processes on evolution -- 9. Development and evolution intertwined.

Additional Edition: Print version: ISBN 9780521516297

Language: English

URL: https://doi.org/10.1017/CBO9780511842382

UID:

Format: 1 online resource (299 pages)

ISBN: 9780191632952 (e-book)

Note: Includes index.

Additional Edition: Print version: Gluckman, Peter D. Fat, fate & disease : why exercise and diet are not enough. New York, New York : Oxford University Press, c2012 ISBN 9780199644629

Language: English

Keywords: Electronic books.

URL: Click to View

UID:

Format: IX, 156 S. , Ill., graph. Darst.

Edition: 1. publ.

ISBN: 9780521516297 , 9780521736206

Note: Includes bibliographical references and index

Language: English

Subjects: Biology

Keywords: Evolutionsbiologie ; Epigenesistheorie

URL: Cover

Author information: Gluckman, Peter D. 1949-

Author information: Bateson, Paul Patrick Gordon 1938-2017

UID:

Format: 1 Online-Ressource (XVI, 230 Seiten) : , Illustrationen, Diagramme.

ISBN: 978-3-318-02270-4

Series Statement: Nestlé Nutrition Workshop series Vol. 71

Content: Growth in mammals encompasses several stages, from intrauterine growth through infancy and childhood to adolescence. Each of these phases is characterized by very specific nutritional, molecular and endocrine perspectives which, under ideal conditions, allow the organism to achieve its genetically programmed growth patterns.In this book, an international panel of experts addresses these topics in a historical, physiological and social perspective. The first part investigates the genetic, epigenetic, molecular and nutritional determinants of intrauterine and postnatal growth. Part two deals with non-evolutionary changes which occurred in the recent past, such as changes in body size in utero, during infancy and childhood, and during adolescence, and the potentially unfavorable consequences of enhanced nutrition and growth, including early onset of puberty, development of obesity, and increases in metabolic and cardiovascular disease. The last part addresses the question of which factors define healthy growth in light of the influence of nutritional, molecular and endocrine influences. Although the association between rapid changes in body size and adverse health effects is clear, the precise nature of causality remains uncertain. Presenting the latest scientific findings in growth research, this publication provides essential reading for pediatricians, clinical investigators and health workers

Note: The experts view

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-318-02269-8

Language: English

Subjects: Medicine

Keywords: Konferenzschrift

DOI: 10.1159/isbn.978-3-318-02270-4

URL: Volltext

Author information: Gluckman, Peter D., 1949-

UID:

Format: ix, 156 p. : , ill.

Edition: Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.

Language: English

Keywords: Electronic books.

URL: Click to View

UID:

Format: 1 online resource (247 p.)

ISBN: 3-318-02270-5

Series Statement: Nestlé Nutrition Institute workshop series, volume 71

Content: Growth in mammals encompasses several stages, from intrauterine growth through infancy and childhood to adolescence. Each of these phases is characterized by very specific nutritional, molecular and endocrine perspectives which, under ideal conditions, allow the organism to achieve its genetically programmed growth patterns. In this book, an international panel of experts addresses these topics in a historical, physiological and social perspective. The first part investigates the genetic, epigenetic, molecular and nutritional determinants of intrauterine and postnatal growth. Part two deals with non-evolutionary changes which occurred in the recent past, such as changes in body size in utero, during infancy and childhood, and during adolescence, and the potentially unfavorable consequences of enhanced nutrition and growth, including early onset of puberty, development of obesity, and increases in metabolic and cardiovascular disease. The last part addresses the question of which factors define healthy growth in light of the influence of nutritional, molecular and endocrine influences. Although the association between rapid changes in body size and adverse health effects is clear, the precise nature of causality remains uncertain. Presenting the latest scientific findings in growth research, this publication provides essential reading for pediatricians, clinical investigators and health workers.

Note: Description based upon print version of record. , ""Cover""; ""Front Matter""; ""Contents""; ""Preface""; ""Foreword""; ""Contributors""; ""Drivers of Growth""; ""Early Influences of Nutrition on FetalGrowth""; ""Abstract""; ""Macronutrient Interventions That Have Varied Energy""; ""Nutrient Interventions That Do Not Vary Energy""; ""Conclusions""; ""References""; ""Early Influences of Nutritionon Postnatal Growth""; ""Abstract""; ""Postnatal Diet, Growth Patterns, and the Later Risk of Obesity and Related Non-Communicable Diseases""; ""Protective Effects of Breastfeeding on Obesity Risk in Later Life"" , ""Mechanisms of Protective Effects of Breastfeeding: The �Early Protein Hypothesis�""""Biochemical and Endocrine Markers""; ""Conclusions""; ""Appendix""; ""Acknowledgements""; ""References""; ""Genome-Wide Association Studies of Human Growth Traits""; ""Abstract""; ""Introduction""; ""The First Successes for GWA Studies of Growth Traits � FTO and HMGA2""; ""Increasing Sample Size by Collaboration and Meta-Analysis Identifies Hundreds of Loci for Adult Height and Other Anthropometric Traits""; ""GWA Studies of Early Growth""; ""GWA Studies of Pubertal Growth"" , ""The Genetics of Growth Is More Complex Than Previously Appreciated""""What GWA Studies Have Not Told Us � The Missing Heritability""; ""Conclusions""; ""References""; ""Discussion on Nutrition and Genetics""; ""Nutrition""; ""Genetics""; ""IGF- I in Human Growth: Lessons from Defects in the GH-IGF-I Axis""; ""Abstract""; ""Normal Human Growth Is Dependent on IGF-I""; ""The Human GH-IGF-I Axis in Human Growth""; ""Defects in the GH-IGF Axis: What Gene Analyses Reveal""; ""Conclusions""; ""References""; ""Non-Imprinted Epigenetics in Fetal and Postnatal Development and Growth"" , ""Abstract""""References""; ""Epigenetic Anomalies in Childhood Growth Disorders""; ""Abstract""; ""Introduction""; ""Russell-Silver Syndrome""; ""Beckwith-Wiedemann Syndrome""; ""Human Multilocus Imprinting Disorders""; ""Assisted Reproductive Technologies and Loss of Imprinting""; ""Conclusion""; ""References""; ""Early Growth and Development of Later Life Metabolic Disorders""; ""Abstract""; ""Introduction""; ""Physiology of Growth""; ""Epidemiological Evidence of Early-Life Developmental Programming""; ""Genetic Factors Modulating Growth and Metabolic Disorder"" , ""Epigenetic Programming""""Other Postulated Mechanisms""; ""Leptin and the GH-IGF Axis""; ""Uncertainties""; ""References""; ""Summary on Drivers of Growth""; ""Secular Trends in Growth""; ""Human Growth: Evolutionary and Life History Perspectives""; ""Abstract""; ""Some General Evolutionary Principles""; ""The Role of Developmental Plasticity""; ""Life History Theory""; ""Heritability, Genetics, Non-Genetic Inheritance and Phenotypic-Driven Evolution""; ""An Evolutionary and Life History Perspective on Human Growth""; ""Puberty""; ""Adolescence""; ""Final Remarks""; ""Appendix"" , ""Acknowledgements"" , English

Additional Edition: ISBN 3-318-02269-1

Language: English