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  • 1
    UID:
    edochu_18452_13117
    ISSN: 1437-4331 , 1437-4331
    Content: Background: Ras homologous (Rho) family GTPases play a pivotal role in the regulation of numerous cellular functions associated with malignant transformation and metastasis. To evaluate the role of these GTPases in colorectal cancer, the mRNA expression levels in matched sets of tumor and non-tumor tissues from surgical specimens were analyzed. The relationship between the mRNA levels in tumor tissues to the clinicopathological features was also assessed. Methods: A total of 68 patients with colorectal carcinoma were recruited and the levels of RhoA and RhoC mRNA transcripts in cancer, paratumoral and normal tissues were characterized by quantitative real-time polymerase chain reaction (QRT-PCR). Their correlation to clinical histopathological parameters was analyzed. Results: The levels of RhoA and RhoC mRNA transcripts in carcinoma tissues were significantly higher than those in the matched paratumor and normal tissues from the same patient (p<0.05). The expression levels of both genes were significantly correlated with metastasis of cancer cells to lymph nodes and liver (p<0.05). The levels of RhoA expression were significantly correlated with the histopathological degree of cancer, while the expression of RhoC was correlated with the extent of local invasion to intestine. Conclusions: This is the first study with QRT-PCR to examine the expressions of RhoA and RhoC genes in colorectal carcinoma of Chinese patients. The significantly up-regulated RhoA and RhoC expressions suggest that they may contribute to the initiation, development, invasion and metastasis of colorectal carcinoma in Chinese patients. Clin Chem Lab Med 2009;47:811–7.
    Content: Peer Reviewed
    In: Clinical Chemistry and Laboratory Medicine, : de Gruyter, 2009, 47,2009,7, Seiten 811-817, 1437-4331
    Language: Undetermined
    URL: Volltext  (kostenfrei)
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  • 2
    Book
    Book
    tai bei
    UID:
    gbv_1039659365
    Format: 3,350 S.
    Original writing title: 古典小说论稿 : 神话、心理、怪诞
    Original writing person/organisation: 刘燕萍
    Original writing publisher: 台北 : 台湾商务印书馆
    ISBN: 9570520698
    Series Statement: 新万有文库 = New variety
    Note: SBB-PK Berlin
    Language: Chinese
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  • 3
    UID:
    gbv_525803831
    Format: XXXVII, 355 S , graph. Darst
    ISBN: 0810859157 , 9780810859159
    Series Statement: Libraries and librarianship: an international perspective 3
    Note: Includes bibliographical references and index , Comparative librarianship / L.K. Sami -- International LIS research : a comparison of national trends / Maxine Rochester and Pertti Vakkari -- Comparison between P.R. China and USA in the field of library and information science / Weina Hua -- Introducing an international cooperative research method employed in cross-country studies in information & library science / Yan Quan Liu -- The impact of national policy on developing information infrastructure nationwide issues in P.R. China and the U.S. / Yan Quan Liu -- Comparing approaches : telecentre evaluation experiences in Asia and Latin America / R. Gomez & K. Reilly -- Is the education on digital libraries adequate? / Yan Quan Liu -- An investigation of LIS qualifications throughout the world / P. Dalton & K. Levinson -- A comparative study of library and information science education : China and the United States / Ziming Liu -- A comparison study on the confusion and threat of the United States and Chinese library education / Xudong Jin -- A comparative case study of graduate courses in library and information studies in the UK, USA, India, and Iran : lessons for Iranian LIS professionals / L. Mortezaie & N. Naghshineh -- Motivation to manage : a comparative study of male and female library & information science students in the United States of America, India, Singapore & Japan / S.R. Murgai -- Digital library infrastructure : a case study on sharing information resources in China / Yan Quan Liu & Jin Zhang -- Cataloging non-print resources in the United States and China : a comparative study of organization and access for selected electronic and audiovisual resources / Yan Ma, Steven Miller & Yan Quan Liu -- The use of new technologies in reference and information work : a survey of training needs in China and New Zealand / R. Cullen & C. Huanwen -- International perspectives on academic libraries : introduction / R. Cullen & P.J. Calvert -- A comparative study of the use of the academic libraries by undergraduates in the United States and Taiwan / Ting-Ming Lai -- International public library trends / Nerida Clifford -- The use of the national library statistics by public library directors / Yan Quan Liu & Douglas L. Zweizig -- National public library statistics and management : a comparison between the United States and People's Republic of China / Yan Quan Liu -- Teachers' perceptions of school libraries : comparisons from Tokyo and Honolulu / Yuriko Nakamura -- An international study on principal influence and information services in schools : synergy in themes and methods / James Henri, Lyn Hay & Dianne Oberg
    Language: English
    Keywords: USA ; Bibliothekswissenschaft ; Asien ; USA ; Informations- und Dokumentationswissenschaft ; Asien ; Aufsatzsammlung
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  • 4
    UID:
    gbv_1039685536
    Format: S.353-619 , 地图
    Edition: 据 1934 年铅印本影印
    Original writing title: 霸县新志 八卷 : 民国
    Original writing person/organisation: 刘延昌
    Original writing publisher: 上海 : 上海书店出版社
    Series Statement: zhong guo di fang zhi ji cheng / he bei fu xian zhi ji 26,3
    Note: SBB-PK Berlin
    Language: Chinese
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  • 5
    Book
    Book
    shang hai
    UID:
    gbv_1039685773
    Format: S.279-526
    Edition: 据 1932 年铅印本影印
    Original writing title: 徐水县新志 十二卷卷末 : 民国
    Original writing person/organisation: 刘延昌
    Original writing publisher: 上海 : 上海书店出版社
    Series Statement: zhong guo di fang zhi ji cheng / he bei fu xian zhi ji 38,2
    Note: SBB-PK Berlin
    Language: Chinese
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  • 6
    Book
    Book
    tai bei
    UID:
    gbv_1034396145
    Format: 490 S.
    Original writing title: 从传统到现代 : 戏曲本质论集
    Original writing person/organisation: 刘彦君
    Original writing publisher: 台北 : 国家出版社
    ISBN: 9789573611875
    Series Statement: guo jia xi qu yan jiu cong shu 44
    Note: SBB-PK Berlin
    Language: Chinese
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  • 7
    Book
    Book
    wu chang
    UID:
    gbv_103309398X
    Format: 3, 4, 424 S. , 图
    Original writing title: 母亲身份研究读本 : = A theoretical reader in motherhood
    Original writing person/organisation: 刘岩
    Original writing publisher: 武昌 : 武汉大学出版社
    ISBN: 9787307055285
    Content: 附参考文献
    Note: Text auch in engl. Spr , SBB-PK Berlin
    Language: Chinese
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  • 8
    Book
    Book
    wu han
    UID:
    gbv_1033089001
    Format: 6, 185 S. , 图
    Original writing title: 旷世文人郁达夫
    Original writing person/organisation: 刘炎生
    Original writing publisher: 武汉 : 湖北人民出版社
    ISBN: 9787216050562
    Note: SBB-PK Berlin
    Language: Chinese
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  • 9
    Book
    Book
    Tai bei : wu nan tu shu chu ban you xian gong si
    UID:
    gbv_1036345041
    Format: 12,483 S.
    Original writing title: 唐律中的夫妻关系
    Original writing person/organisation: 刘燕俪
    Original writing publisher: 台北 : 五南图书出版有限公司
    Series Statement: zhong guo fa zhi shi cong shu 1W60
    Note: 有附录, 参考书目 , SBB-PK Berlin
    Language: Chinese
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  • 10
    UID:
    gbv_1033712159
    Format: 282-290 S.
    Edition: 影印本
    Original writing title: 审拟戍兵林鸿英挟嫌滋事案 : 道光八年八月十七日
    Original writing person/organisation: 刘延斌
    Original writing publisher: 北京 : 九州出版社
    ISBN: 9787801958600
    Series Statement: ming qing gong cang tai wan dang an hui bian 146
    Note: 此档案出于福建台湾镇总兵刘延斌等奏折 , SBB-PK Berlin
    Language: Chinese
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