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  • 1
    Online-Ressource
    Online-Ressource
    Very Low Birth Weight, Infant Growth, and Autism-Spectrum Traits in Adulthood
    American Academy of Pediatrics (AAP) ; 2014
    In:  Pediatrics Vol. 134, No. 6 ( 2014-12-01), p. 1075-1083
    Details
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 134, No. 6 ( 2014-12-01), p. 1075-1083
    Kurzfassung: We examined whether adults born preterm at very low birth weight (VLBW; & lt;1500 g) differ from term-born adults in autism-spectrum traits, and whether among VLBW adults, growth in infancy is associated with these traits. METHODS: A total of 110 VLBW and 104 term-born adults of the Helsinki Study of Very Low Birth Weight Adults completed the Autism-Spectrum Quotient yielding total, social interaction, and attention to detail sum scores. Growth in weight, length, and head circumference from birth to term and from term to 1 year of corrected age was determined as standardized residuals reflecting growth conditional on previous history. RESULTS: VLBW adults scored higher than term-born controls on social interaction sum score, indicating higher autism-spectrum traits. In contrast, they scored lower on attention to detail sum score, indicating lower autism-spectrum traits. Within the VLBW group, faster growth in weight, length, and head circumference from birth to term was associated with lower total and social interaction sum scores. In this group, growth from term to 1 year was not associated with autism-spectrum traits. CONCLUSIONS: Among those born preterm at VLBW, the risk for higher levels of autism-spectrum traits, particularly related to social interaction, may persist into adulthood. Faster growth from birth to term may ameliorate these effects, suggesting that targeted interventions could aid long-term neurodevelopment.
    Materialart: Online-Ressource
    ISSN: 0031-4005 , 1098-4275
    URL: Article
    DOI: 10.1542/peds.2014-1097
    Sprache: Englisch
    Verlag: American Academy of Pediatrics (AAP)
    Publikationsdatum: 2014
    ZDB Id: 1477004-0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Online-Ressource
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  • 2
    Online-Ressource
    Online-Ressource
    Self- and Parent-Rated Executive Functioning in Young Adults With Very Low Birth Weight
    American Academy of Pediatrics (AAP) ; 2013
    In:  Pediatrics Vol. 131, No. 1 ( 2013-01-01), p. e243-e250
    Details
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 131, No. 1 ( 2013-01-01), p. e243-e250
    Kurzfassung: Adults born preterm score lower on performance-based tests of executive functioning (EF) than their term-born peers. These test scores do not necessarily translate to application of these skills in an everyday environment. The objective of the study was to test differences between very low birth weight (VLBW; & lt;1500 g) adults and their term-born peers in self- and parent-rated EF and examine concordance between self- and parent-rated EF and performance-based tests of EF. METHODS: A longitudinal study of 90 VLBW adults and 93 term-born controls (aged 21–30 years) was performed. The young adults and their parents filled in the Behavioral Rating Inventory of Executive Functioning–Adult Version, and the adults underwent performance-based tests of EF. RESULTS: VLBW young adults and especially those born appropriate for gestational age reported fewer problems in behavioral regulation and global EF than term-born controls; however, parents of VLBW adults born small for gestational age reported more problems for their children in all EF scales than parents of the controls. Compared with their parents, VLBW young adults reported fewer problems in behavioral regulation. Adults’ ratings and their parents’ ratings correlated significantly among VLBW and control groups. In the VLBW and VLBW/small-for-gestational-age groups, parent ratings of EF were correlated to performance-based tests, whereas among term-born adults, self-reports correlated. CONCLUSIONS: These findings reveal that VLBW adults may have learned to compensate in the everyday environment for their EF deficits apparent in performance-based tests. Alternatively, VLBW adults may have positively skewed views of their abilities.
    Materialart: Online-Ressource
    ISSN: 0031-4005 , 1098-4275
    URL: Article
    DOI: 10.1542/peds.2012-0839
    Sprache: Englisch
    Verlag: American Academy of Pediatrics (AAP)
    Publikationsdatum: 2013
    ZDB Id: 1477004-0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Late Preterm Birth and Neurocognitive Performance in Late Adulthood: A Birth Cohort Study
    American Academy of Pediatrics (AAP) ; 2015
    In:  Pediatrics Vol. 135, No. 4 ( 2015-04-01), p. e818-e825
    Details
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 135, No. 4 ( 2015-04-01), p. e818-e825
    Kurzfassung: We studied if late preterm birth (34 weeks 0 days–36 weeks 6 days of gestation) is associated with performance on the Consortium to Establish a Registry for Alzheimer’s Disease Neuropsychological Battery (CERAD-NB) in late adulthood and if maximum attained lifetime education moderated these associations. METHODS: Participants were 919 Finnish men and women born between 1934 and 1944, who participated in the Helsinki Birth Cohort Study. They underwent the CERAD-NB at a mean age of 68.1 years. Data regarding gestational age (late preterm versus term) were extracted from hospital birth records, and educational attainment data were gathered from Statistics Finland. RESULTS: After adjustment for major confounders, those born late preterm scored lower on word list recognition (mean difference: –0.33 SD; P = .03) than those born at term. Among those who had attained a basic or upper secondary education, late preterm birth was associated with lower scores on word list recognition, constructional praxis, constructional praxis recall, clock drawing, Mini–Mental State Examination, and memory total and CERAD total 2 compound scores (mean differences: & gt;0.40 SD; P values & lt;.05), and had a 2.70 times higher risk of mild cognitive impairment (Mini–Mental State Examination score: & lt;26 points) (P = .02). Among those with tertiary levels of education, late preterm birth was not associated with CERAD-NB scores. CONCLUSIONS: Our findings offer new insight into the lifelong consequences of late preterm birth, and they add late preterm birth as a novel risk factor to the list of neurocognitive impairment in late adulthood. Our findings also suggest that attained lifetime education may mitigate aging-related neurocognitive impairment, especially among those born late preterm.
    Materialart: Online-Ressource
    ISSN: 0031-4005 , 1098-4275
    URL: Article
    DOI: 10.1542/peds.2014-3556
    Sprache: Englisch
    Verlag: American Academy of Pediatrics (AAP)
    Publikationsdatum: 2015
    ZDB Id: 1477004-0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Online-Ressource
    Online-Ressource
    Short Sleep Duration and Behavioral Symptoms of Attention-Deficit/Hyperactivity Disorder in Healthy 7- to 8-Year-Old Children
    American Academy of Pediatrics (AAP) ; 2009
    In:  Pediatrics Vol. 123, No. 5 ( 2009-05-01), p. e857-e864
    Details
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 123, No. 5 ( 2009-05-01), p. e857-e864
    Kurzfassung: OBJECTIVE. It has been hypothesized that sleep deprivation may manifest in children as behavioral symptoms rather than as tiredness, but only a few studies have investigated this hypothesis. The objective of our study was to evaluate whether short sleep is associated with behavioral symptoms of attention-deficit/hyperactivity disorder in 7- to 8-year-old children. METHODS. We performed a cross-sectional study of children born in 1998 in Helsinki, Finland. The participants included 280 (146 girls, 134 boys) children with a mean age of 8.1 years (SD: 0.3; range: 7.4–8.8). Sleep quality was measured by using actigraphs. The Sleep Disturbance Scale for Children and the Attention-Deficit/Hyperactivity Disorder Rating Scale IV were administered to parents. RESULTS. Children whose average sleep duration as measured by actigraphs was short ( & lt;10th percentile, ie, & lt;7.7 hours) and had a higher hyperactivity/impulsivity score (9.7 vs 7.8 or 7.5) and a higher attention-deficit/hyperactivity disorder total score (17.3 vs 14.5 or 13.1) but a similar inattention score (7.6 vs 6.7 or 5.6) compared with children sleeping 7.7 to 9.4 hours or & gt;9.4 hours. In multivariate statistical models, short sleep duration remained a statistically significant predictor of hyperactivity/impulsivity, and sleeping difficulties were associated with hyperactivity/impulsivity, inattention, and the total score. There were no significant interactions between short sleep and sleeping difficulties. CONCLUSIONS. Children's short sleep duration and sleeping difficulties increase the risk for behavioral symptoms of attention-deficit/hyperactivity disorder.
    Materialart: Online-Ressource
    ISSN: 0031-4005 , 1098-4275
    URL: Article
    DOI: 10.1542/peds.2008-2164
    Sprache: Englisch
    Verlag: American Academy of Pediatrics (AAP)
    Publikationsdatum: 2009
    ZDB Id: 1477004-0
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