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  • Cambridge University Press (CUP)  (630)
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  • Cambridge University Press (CUP)  (630)
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  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2002
    In:  The Journal of Laryngology & Otology Vol. 116, No. 9 ( 2002-09), p. 690-694
    In: The Journal of Laryngology & Otology, Cambridge University Press (CUP), Vol. 116, No. 9 ( 2002-09), p. 690-694
    Abstract: Paediatric revision myringoplasty has received little attention. This study addressed the issue exclusively and reviewed the short- and long-term results of surgery in children between the ages of five and 15. Twenty-six out of 38 operated ears (68.4 per cent) were initially intact. The causes of immediate failure in decreasing order were: infection with graft necrosis, complete no-take of the graft and poor anterior adaptation of the graft. Age, size and site of perforation and surgeon’s experience did not significantly affect the initial outcome of surgery. Six ears developed delayed re-perforations, thus decreasing the overall success rate to 52.6 per cent. The latter were attributable to either episodes of acute otitis media or to insidious atrophy of the tympanic membrane. Notably, none developed post-operative sensorineural hearing loss. It is concluded that the results of paediatric revision myringoplasty are rather disappointing, yet arguments encouraging its practice are favourably presented.
    Type of Medium: Online Resource
    ISSN: 0022-2151 , 1748-5460
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2002
    detail.hit.zdb_id: 2013209-8
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  • 2
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1972
    In:  Worldview Vol. 15, No. 7 ( 1972-07), p. 20-25
    In: Worldview, Cambridge University Press (CUP), Vol. 15, No. 7 ( 1972-07), p. 20-25
    Abstract: Of all evils in American society, racial oppression is the most intolerable. Of all priorities for American society, the attainment of racial justice is the most urgent. This is so because the issue of race touches on the very heart of the moral values by which the society lives. Martin Luther King understood this, and the same understanding illuminates his idea of an integrated American society. The ideal is not only the integration of black Americans in terms of all the rights and privileges promised by the society's political creed; and it is not at all integration that deprives blacks of their cultural identity, as King's detractors (including the posthumous ones) have falsely claimed.
    Type of Medium: Online Resource
    ISSN: 0084-2559
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1972
    SSG: 1
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2016
    In:  Expert Reviews in Molecular Medicine Vol. 18 ( 2016)
    In: Expert Reviews in Molecular Medicine, Cambridge University Press (CUP), Vol. 18 ( 2016)
    Abstract: Necrotising enterocolitis (NEC) is an uncommon, but devastating intestinal inflammatory disease that predominantly affects preterm infants. NEC is sometimes dubbed the spectre of neonatal intensive care units, as its onset is insidiously non-specific, and once the disease manifests, the damage inflicted on the baby's intestine is already disastrous. Subsequent sepsis and multi-organ failure entail a mortality of up to 65%. Development of effective treatments for NEC has stagnated, largely because of our lack of understanding of NEC pathogenesis. It is clear, however, that NEC is driven by a profoundly dysregulated immune system. NEC is associated with local increases in pro-inflammatory mediators, e.g. Toll-like receptor (TLR) 4, nuclear factor-κB, tumour necrosis factor, platelet-activating factor (PAF), interleukin (IL)-18, interferon-gamma, IL-6, IL-8 and IL-1β. Deficiencies in counter-regulatory mechanisms, including IL-1 receptor antagonist (IL-1Ra), TLR9, PAF-acetylhydrolase, transforming growth factor beta (TGF-β) 1 & 2 , IL-10 and regulatory T cells likely facilitate a pro-inflammatory milieu in the NEC-afflicted intestine. There is insufficient evidence to conclude a predominance of an adaptive Th1-, Th2- or Th17-response in the disease. Our understanding of the accompanying regulation of systemic immunity remains poor; however, IL-1Ra, IL-6, IL-8 and TGF-β 1 show promise as biomarkers. Here, we chart the emerging immunological landscape that underpins NEC by reviewing the involvement and potential clinical implications of innate and adaptive immune mediators and their regulation in NEC.
    Type of Medium: Online Resource
    ISSN: 1462-3994
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 2035515-4
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  • 4
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2015
    In:  Palliative and Supportive Care Vol. 13, No. 3 ( 2015-06), p. 653-660
    In: Palliative and Supportive Care, Cambridge University Press (CUP), Vol. 13, No. 3 ( 2015-06), p. 653-660
    Abstract: Individuals with life-threatening illness often engage in some form of spirituality to meet increased needs for meaning and purpose. This study aimed to identify the role of spirituality in persons who had reported positive, life-transforming change in relation to life-threatening cancer or cardiac events, and to connect these roles to palliative and supportive care. Method: A purposive sample of 10 cardiac survivors and 9 cancer survivors was recruited. Once the participants had given informed consent and passed screening in relation to life-transforming change and distress, they engaged in a semistructured one-hour qualitative interview on the theme of how their life-transforming change occurred in the context of their life-threatening illness. In the present article, our phenomenological analysis focuses on participants' references to purpose and meaning in their lives, with particular attention to the role and context of participants' spirituality. Results: Participants mentioned spirituality, meaning, and purpose in many contexts, including connecting with family and friends, nature, art, music, and sometimes creating a relationship with God. Participants often accessed spirituality by enhancing connections in their own lives: with a higher power, people, their work, or themselves. These enhanced connections gave participants greater meaning and purpose in their lives, and substantially helped participants to adjust to their life-threatening illnesses. Significance of results: Understanding the roles and contexts of spirituality among patients with a life-threatening illness allows us to develop better palliative and supportive care plans. Spiritually oriented supportive care may include support groups, yoga, meditation, nature, music, prayer, or referral to spiritual or religious counselors. A quantitative scale is needed to help healthcare clinicians assess the spiritual and coping needs of individuals with life-threatening illness.
    Type of Medium: Online Resource
    ISSN: 1478-9515 , 1478-9523
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2015
    detail.hit.zdb_id: 2121158-9
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  • 5
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1948
    In:  Tempo , No. 9 ( 1948), p. 20-27
    In: Tempo, Cambridge University Press (CUP), , No. 9 ( 1948), p. 20-27
    Abstract: Aaron Copland's Third Symphony, completed in 1946 after some two years of concentrated labour, comes at the end of more than a decade during which his orchestral efforts were either in response to commissions in the field of ballet ( Billy the Kid, Rodeo and Appalachian Spring ) or cinema ( Our Town ), contrived to underline spoken text ( Lincoln Portrait ) or transmit impressions of travel ( El Salón México, Danzón Cubano ) or otherwise restricted by exterior factors (e.g., Second Hurricane and Outdoor Overture , intended for performance by school children). The degree to which he maintained his integrity and the quality and self-subsistence of his music through all these pièces d'occasion is quite astonishing. But it is, all the same, highly gratifying, and in the realm of the most notable musical occurrences, that he has finally found the leisure (through a commission from the Koussevitsky Foundation) to write a full-length symphony (some forty minutes in duration), a work that has not, either in seriousness or dimension, been obliged to compromise in the slightest with an impresario or any other demands of an occasion or dramatic situation.
    Type of Medium: Online Resource
    ISSN: 0040-2982 , 1478-2286
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1948
    detail.hit.zdb_id: 2067089-8
    SSG: 9,2
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  • 6
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2016
    In:  Palliative and Supportive Care Vol. 14, No. 6 ( 2016-12), p. 680-685
    In: Palliative and Supportive Care, Cambridge University Press (CUP), Vol. 14, No. 6 ( 2016-12), p. 680-685
    Abstract: The goal of this pilot study was to identify the processes by which healing occurs in patients who experience a life-threatening illness. Method: Healing was examined by using two qualitative studies that employed a semistructured interview process (interviews lasted between 30 and 115 minutes). There were 10 cardiac event survivors and 9 cancer survivors. These participants came from a community hospital setting (cardiac), nonmedical holistic services organization (cancer), and a research hospital (cancer). Before participants could take part in the study, they were administered preliminary screening measurements, the first of which was an instrument similar to the Distress Thermometer. Participants then self-reported their positive life-transforming changes. If one to three changes were reported six months after onset of the illness, participants were deemed to have passed the screening. Finally, participants were tested for speaking volume and clarity. Results: An overall theme that was prevalent throughout the interviews was medical support. Participants found that their positive, life-transforming changes were typically connected with supportive caregivers who helped to create a culture of care. They also indicated that an absence of this medical supportive care hindered development of such life-transforming changes. Significance of Results: Our results indicate that a medical care team will be more effective if a positive culture of care is created. This can be implemented if the team provides comfort, which involves being more engaged in the treatment of patients as well as being more attentive to their psychosocial needs.
    Type of Medium: Online Resource
    ISSN: 1478-9515 , 1478-9523
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 2121158-9
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  • 7
    In: The Journal of Economic History, Cambridge University Press (CUP), Vol. 40, No. 4 ( 1980-12), p. 859-861
    Type of Medium: Online Resource
    ISSN: 0022-0507 , 1471-6372
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1980
    detail.hit.zdb_id: 3050-8
    detail.hit.zdb_id: 1495598-2
    SSG: 7,26
    SSG: 19,2
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  • 8
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2023
    In:  The Journal of Economic History Vol. 83, No. 2 ( 2023-06), p. 431-463
    In: The Journal of Economic History, Cambridge University Press (CUP), Vol. 83, No. 2 ( 2023-06), p. 431-463
    Abstract: We use historical census data to show that Sweden exhibited high levels of intergenerational occupational mobility several decades before the rise of the welfare state. Mobility rates were higher than in other nineteenth- and twentieth-century European countries, closer to those observed in the highly mobile nineteenth-century United States. We leverage mobility variation across Swedish municipalities to shed light on potential determinants: economic growth and migration are positively correlated with mobility, consistent with the patterns observed across countries.
    Type of Medium: Online Resource
    ISSN: 0022-0507 , 1471-6372
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 3050-8
    detail.hit.zdb_id: 1495598-2
    SSG: 7,26
    SSG: 19,2
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  • 9
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2009
    In:  Geological Magazine Vol. 146, No. 2 ( 2009-03), p. 173-186
    In: Geological Magazine, Cambridge University Press (CUP), Vol. 146, No. 2 ( 2009-03), p. 173-186
    Abstract: The Amalaoulaou Neoproterozoic island-arc massif belongs to the Gourma belt in Mali. The metagabbros and pyroxenites forming the main body of this arc root show the pervasive development of garnet. In the pyroxenites, the latter has grown by reaction between pyroxene and spinel during isobaric cooling. By contrast, in the metagabbros, garnet textures and relations to felsic veins exclude an origin through solid-state reactions only. It is proposed that garnet has grown following dehydration and localized melting of amphibole-bearing gabbros at the base of the arc. The plagioclase-saturated melts represented by anorthositic veins in the metagabbros and by trondhjemites in the upper part of the massif provide evidence for melting in the deep arc crust, which locally generated high-density garnet–clinopyroxene–rutile residues. Garnet growth and melting began around 850 °C at 10 kbar and the tonalitic melts were most probably generated around 1050 °C at P ≥ 10 kbar. This HT granulitic imprint can be related to arc maturation, leading to a P – T increase in the deep arc root and dehydration and/or dehydration-melting of amphibole-bearing gabbros. Observation of such features in the root of this Neoproterozoic island arc has important consequences, as it provides a link to models concerning the early generation of continental crust.
    Type of Medium: Online Resource
    ISSN: 0016-7568 , 1469-5081
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2009
    detail.hit.zdb_id: 956405-6
    detail.hit.zdb_id: 1479206-0
    SSG: 13
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  • 10
    In: The Journal of Economic History, Cambridge University Press (CUP), Vol. 28, No. 3 ( 1968-09), p. 490-492
    Type of Medium: Online Resource
    ISSN: 0022-0507 , 1471-6372
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1968
    detail.hit.zdb_id: 3050-8
    detail.hit.zdb_id: 1495598-2
    SSG: 7,26
    SSG: 19,2
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