Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • dissertations  (2,677)
Type of Medium
  • dissertations  (2,677)
Language
Year
Journal
  • 1
    Dissertation
    Dissertation
    University of Glasgow
    Language: English
    Description: The cladiellins (also known as eunicellins) are oxygen-bridged 2,11–cyclised cembranoids, isolated from gorgonian octocorals and soft corals. They present an unusual oxatricyclic ring system composed of a hydroisobenzofuran and an oxonene unit. The natural role of these cembranoids is proposed to involve predatation deterrence, and biologically they have been shown to exhibit in vitro cytotoxicity against various cancer cell lines, anti inflammatory properties antimicrobial activities. The Clark group has been interested in the synthesis of cladiellins for some time, and in 2007 Clark and co-workers reported the total synthesis of vigulariol. This thesis describes the investigation of the synthesis of both E- and Z-cladiellins using our general strategy. The key transformations in the synthetic route are ring formation reactions. Firstly, a SmI2-mediated reductive cyclisation forms the tetrahydropyran ring, then a tandem oxonium ylide formation [2,3]-sigmatropic rearrangement constructs the oxabicyclo[6.2.1]undecenone bicyclic core. Finally, a Diels-Alder cycloaddition reaction forms the third ring of the tricyclic core of the cladiellins. Particular interest was given to the tandem oxonium ylide formation [2,3]-sigmatropic rearrangement reaction. This transformation was studied in order to develop conditions allowing the selective formation of the E-oxonene ring needed for the synthesis of the E-cladiellin tricyclic core. Herein, is presented work towards the synthesis of ophirin B, a cladiellin bearing a Z-oxonene alkene, as well as the enantioselective total synthesis of eight cladiellins obtained from an E-cladiellin tricyclic core: (−)-cladiella-6,11-dien-3-ol, (−)-cladiell-11-ene-3,6,7-triol, (−)-3-acetoxycladiella-6,11-diene, 3-acetoxy-cladiellin-11-ene-6,7-diol, (−)-sclerophytin A, (−)-sclerophytin B, (+)-deacetylpolyanthellin A and (+)-polyanthellin A in 20 to 24 steps from our allylic alcohol precursor.
    Keywords: 547.7 ; Qd Chemistry
    Source: The British Library
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Language: German
    Keywords: Jahresabschluss ; Elektronischer Datenaustausch
    ISBN: 9783830065029
    Source: Deutsche Zentralbibliothek für Wirtschaftswissenschaften
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Language: English
    In: Doctoral thesis, UCL (University College London).
    Description: This thesis examines the involvement of Alfred Stieglitz – photographer, editor, art collector, impresario, talker – and his circle in the development of American modernism in the first three decades of the twentieth century. Through the analysis of photographs and artworks in other media by the Stieglitz group, the journal Camera Work, the gallery 291, a vast correspondence and art theory, criticism and social thought of the period, Stieglitz and his circle are situated in the context of an international debate about modernism. Notably, the Stieglitz strand of American modernism is considered in terms of a dialogue with German culture and philosophy, constellations that, it is claimed, proved formative for Stieglitz. The thesis argues that underlying all of his various endeavours is a specific unifying structure of thought: the romantic critique of capitalism. Romantic anti-capitalism was particularly current at the time in Central Europe as an emotional response to modernity that drew its values from the past. Most poignantly, Georg Lukács expressed it in his early, pre-Marxist writings, such as the essay collection, Soul and Form (first published in German in 1911). It is equally the aim of this thesis to theorise the interpretive category of romantic anti-capitalism, to investigate it as a Weltanschauung, an ideology and a type of discourse. As a period term itself, the category of worldview, poses a problem in its overlap with the topic of the study. It is hence treated both as a method and as an object of enquiry. Romantic anti- capitalism as a whole, neither clearly progressive nor reactionary in political terms and inherently ambiguous, allows us to disentangle the myths that have been reiterated in many previous studies of Stieglitz and his circle and define his outlook with new precision.
    Source: University College London (UCL)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Language: English
    Description: This study analyses the trajectory of literary representions of flight and expulsion from the 1950s until the present. The expulsion of ethnic Germans from the former eastern territories at the end of the Second World War has been thematised in a vast body of German literature, yet it has only recently attracted substantial critical attention when the topic experienced a resurgence in the media and literature in the Berlin Republic. This thesis charts the development of fictional narratives of German wartime suffering since the early postwar years and examines the most recent wave of novels in light of the earlier texts. Drawing on recent scholarship that dismisses the widely held notion that the subject had until now been 'taboo' in the Federal Republic, this study argues that memories of German wartime suffering have consistently found expression in the public sphere since the immediate aftermath of the war. The subsequent examination of expulsion novels thus takes a long-term perspective, considering the trajectory of expulsion literature over several decades, and evaluating the recent texts as part of a long tradition of representations in German literature. The novels are viewed both within the context of their respective historical period, as well as in relation to each other, enabling a more inclusive and comprehensive perspective. Moreover, this study includes a wide range of texts, including popular literature, complementing conventional literary history and offering a broader and more differentiated discussion than hitherto provided by scholarship on the subject. Framed by a discussion ofthe broader memory discourse surrounding German wartime suffering, it is argued that literature is a key medium for reflections on German victimhood, especially the wave of recent texts, which coincides with a period of transition as first-hand witnesses die out and other forms of remembrance take on increasing significance.
    Keywords: 830.900914
    Source: The British Library
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Language: German
    Description: An apdapted and optimized contrast enhanced elliptic centric ordered 3D MR venography technique was compared to a 2D time-of-flight MR venography in 25 patients (mean age 40.6 +/- 16.5 years) with presumptive cerebral venous sinus thrombosis and evaluated for image quality, assessment of various sinus and internal cerebral veins as well as for additional imaging procedures required.The modified contrast enhanced elliptic centric ordered 3D MR venography with fluoroscopic triggering and a substraction technique performed superior in terms of image quality as well as assessment of all sinus and veins except for the straight sinus. Additional imaging procedures were less often required in contrast enhanced elliptic centric ordered 3D MR venography studies.Sensitivity/specificity of contrast enhanced elliptic centric ordered 3D MR venography amounted to 85.7%/97.2% as compared with 2D time-of-flight MR venography 71.4%/55.6 %. The results provide additional evidence for the superiority of contrast enhanced elliptic centric ordered 3D MR venography compared with 2D time-of-flight MR venography for the diagnosis or exclusion of acute cerebral venous sinus thrombosis in daily clinical practice.
    Keywords: 610 Medizin Und Gesundheit ; 610 Medical Sciences; Medicine ; Ddc:610 ; Cerebral Venous And Sinus Thrombosis ; Magnetic Resonance Imaging ; Venography
    Source: Freie Universitat Berlin
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Dissertation
    Dissertation
    Berlin: Freie Universität Berlin Universitätsbibliothek
    Language: German
    Description: Polyamines, namely spermidine and spermine, are important regulators of basic cell functions which are also involved with specific functions in the mammalian brain. Accordingly, polyamines as well as the enzymes for polyamine synthesis and degradation are differentially distributed in neurons and glial cells in the respective brain areas. The precursor of spermidine/spermine synthesis, the diamine putrescine, can be synthesised via two different pathways, refered to as the "classical" and the "alternative" pathway. While in the classical pathway urea and carbon dioxide are removed from the amino acid arginine catalysed by arginase and ornithine decarboxylase, yielding putrescine, the alternative pathway, by first removing carbon dioxide by arginine decarboxlyase and then urea by agmatinase, may also supply the precursor for spermidine/spermine synthesis. To examine the expression pattern of arginase in the rat brain, in this study a polyclonal monospecific antibody was characterized by purification of a raw serum raised against arginase 1. Using the purified antibody, the expression of arginase was analysed in cerebral cortex, hippocampus, thalamus, hypothalamus, mesencephalon, metencephalon and in the basal ganglia at a cellular and subcellular level. In contrast to other polyamine metabolic enzymes, such as the downstream enzymes agmatinase and spermidine synthase, the pathway entry enzymes arginase and arginine decarboxylase are clearly more widely distributed in rat brain neurons. In order to evaluate the significance of either the classical or the alternative pathway for polyamine synthesis in rat brain, the resulting labeling patterns for arginase were compared with those for agmatinase, spermidine synthase and arginine decarboxylase. With regard to the observed distribution patterns, it seems likely that the synthesis of agmatine rather than putrescine may be the main purpose of the alternative pathway of polyamine synthesis. By contrast, spermidine/spermine synthesis may mainly be fueled by the classical pathway.
    Keywords: 610 Medizin Und Gesundheit ; 610 Medical Sciences; Medicine ; Ddc:610 ; Arginase ; Polyamines ; Rat Brain ; Polyamine Pathways ; Antibody
    Source: Freie Universitat Berlin
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Language: English
    Description: This thesis examines the role of social process and routinised violence in the use of underaged soldiers in southern Sudan from the early 1980s to the present day. It draws on accounts of southern Sudanese who as children and teenagers were part of the Red Army, the youth wing of the Sudan People's Liberation Army (SPLA). They received training and/or participated in warfare as part of the organised guerrilla force during a 21- year civil war. By compiling a broad spectrum of recollections and providing a geographical and political context, this thesis endeavours to show the role of social process and routinised violence in the deployment of underaged soldiers by the SPLA. The exploitation of children and youth by senior adult figures within the movement was highly organised and reflected both the gravity, or desperation, of the military situation (Sudan's northern regime used a scorched earth policy and proxies) and cultural mores. I approach the question of the use of youth for military purposes from a socio-cultural perspective, illustrating the ways in which the dominant social mores of southern Sudan contributed towards the marginalisation of youth. They were seen as 'other,' in part through the complex representation of relatedness and hierarchy within the majority Nilotic-speaking peoples of southern Sudan. Within this larger group, strategic interpretation of kinship ties enabled the privileging of some and the disadvantaging of others. The former group is represented, in part, by those who were sent to Cuba in the early years of the war, many of whom were related to senior members of the' SPLA. The latter group, the disadvantaged, either remained within southern Sudan or did not survive the war. A second focus of the thesis is the intended and unintended cultural transformation experienced by members of the Red Army, both those who remained in Sudan and those who were dispatched to Cuba.
    Keywords: 303.6608309629
    Source: The British Library
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Dissertation
    Dissertation
    Univerzita Pardubice
    Language: Czech
    Description: Tato práce se zaměřuje na cykloturistiku v Hradci Králové a jeho okolí. Cílem této práce je zanalyzovat současný stav a navrhnout jeho zlepšení. Je zde zpracována analýza městských lesů, skanzenu v Krňovicích či Labské stezky.
    Keywords: Cykloturistika ; Hradec Králové ; Labská Stezka ; Městské Lesy ; Skanzen Krňovice ; Cycling Tourism ; Hradec Králové ; The Elbe Cycle Route ; Urban Woods ; Open Air Museum Krňovice
    Source: University of Pardubice
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Dissertation
    Dissertation
    Univerzita Pardubice
    Language: Czech
    Description: Diplomová práce obsahuje podmínky vstupu akciové společnosti na burzu cenných papírů. Pojednává o vstupu společnosti Fortuna Entertainment Group N. V. na burzu cenných papírů prostřednictvím prvotní veřejné nabídky akcií. Dále pak zhodnocuje vývoj jejího kurzu od počátku obchodování.
    Keywords: Akcie ; Burza Cenných Papírů ; Prvotní Veřejná Nabídka ; index PX ; Prospekt Emitenta ; Share ; Stock Exchange ; Initial Public Offering ; index PX ; Prospectus
    Source: University of Pardubice
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Language: English
    Source: National Library of Australia (Trove)〈img src=https://exlibris-pub.s3.amazonaws.com/Trove_reload.gif style="vertical-align:middle;margin-left:7px"〉
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages