Format:
Online-Ressource (XIII, 181 p. 37 illus., 17 illus. in color, digital)
ISBN:
9783642337215
,
1299335535
,
9781299335530
Series Statement:
Research and Perspectives in Endocrine Interactions
Content:
In theoretical terms, sex differences in brain and behavior offer the possibility of fascinating scientific studies on a range of molecular phenomena such as DNA methylation, chromatin protein modification, non-coding DNA, resulting in important neuroanatomical and neurochemical effects. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples to be discussed today will include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. The meeting will end with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents
Note:
Description based upon print version of record
,
Multiple Origins of Sex Differences in Brain; Neuroendocrine Functions and their Pathologies; Foreword; Multiple Origins of Sex Differences in Brain. NeuroendocrineFunctions and their Pathologies; Acknowledgments; Contents; Contributors; Hormone-Dependent Chromatin Modifications Related to Sexually Differentiated Behaviors; Introduction; Behaviors; Neuroanatomy; Human Studies; Molecular Mechanisms; Evidence for Epigenetic Regulation; Outlook; References; Importance of Genomic Imprinting in the Evolution and Development of the Maternal Brain; Introduction
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Matrilineal Control Over Genomic ImprintingGenomic Imprinting and Placental Hypothalamic Co-adaptation; A Reconsideration of SRY Evolution and Masculinisation of the Brain; Concluding Comments; References; Genomic Imprinting in the Adult and Developing Brain; Introduction; Genomic Imprinting and Brain Function; Genome-Wide Identification of Parental Effect in Transcription; Conclusion and Perspective; References; The Synapse: Differences Between Men and Women; Introduction; Sexual Dimorphism of the Human Brain; Brain Size and Intellectual Capabilities
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Microanatomical Sex Differences of the Neocortex at the Ultrastructural LevelCytoarchitecture of the Temporal Neocortex from Men and Women; Ultrastructural Analysis; Gender Differences in Synaptic Density of Temporal Neocortex; Caveats; Significance of Sexual Differences in Synaptic Density; References; Gonadal Hormone Influences on Human Neurobehavioral Development: Outcomes and Mechanisms; Introduction; Human Gender Development; Androgen and the Development of the Human Brain and Human Behavior; Socialization and Cognitive Developmental Influences on Human Gender Development
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Cascading Effects of Early Androgen Exposure on Cognitive Understanding of Gender and on Other Aspects of Gender DevelopmentReferences; Congenital Adrenal Hyperplasia: Neuroendocrine, Behavioral and Cognitive Implications; Introduction; CAH: A Model for Sex Hormone Effects on Behavior; CAH and Brain Structure; CAH and Cognition; Prenatal Glucocorticoid Treatment Glucocorticoid Treatment of CAH: Brain Effects; Summary; References; Genetic Variation Within Serotonin Genes, Hormones, and Aggression; Introduction; Heritability of Aggression; Testosterone and Aggression
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Genes and the Serotonin SystemMAOA; Interaction Between MAOA and Environmental Risk Factors; Impact of MAOA Genotype on Neuronal Circuits Moderating Emotional Response and Behavioral Control; Interaction Between MAOA and Testosterone; The Serotonin Receptor B (HTR2B); Conclusions; References; Multiple Origins of Sex Differences in Attention Deficit Hyperactivity Disorder; Introduction; Brief Background; Increasing Trends of Recognition and Treatment; Dimensional and Categorical Assessments of ADHD; Sex Differences in the Longitudinal MTA Study; Conclusions; References
,
Fetal Testosterone in Mind: Implications for Autism
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Donald PFAFF (The Rockefeller University, New York, USA) Hormone-dependent chromatin modifications regulating sexually differentiated animal behaviour -- Eric B. KEVERNE (University of Cambridge, Cambridge, UK) Importance of genomic imprinting in the evolution and development of the maternal brain -- Catherine DULAC (Harvard University & Howard Hughes Medical Institute, Cambridge, USA) Sex battles in the brain: genomic imprinting in the developing and adult CNS -- Javier DE FELIPE (Universidad Politécnica de Madrid, Madrid, Spain) Gender differences in human cortical synaptic density -- Melissa HINES (University of Cambridge, Cambridge, UK) Androgenic influences on human neurobehavioral development: outcomes and mechanisms -- Simon BARON-COHEN (Cambridge University, Cambridge, UK) The foetal androgen theory of autism -- Francesca DUCCI (King’s College, London, UK) Genetic variation within serotonin genes, hormones, and aggression -- Jay GIEDD (National Institute of Mental Health, Bethesda, USA) Does size matter? Sex differences in the developing brain -- Jill GOLDSTEIN (Brigham and Women’s Hospital and Harvard Medical School, Boston, USA) Fetal hormonal programming of the brain: Implications for understanding sex differences in depression and risk for cardiovascular disease -- James SWANSON (University of California, Irvine, USA) Attention deficit hyperactivity disorders: factors contributing to sex differences in recognition and treatment with stimulant medication -- Phyllis W. SPEISER (Hofstra North Shore LIJ School of Medicine, New York, USA) Congenital adrenal hyperplasia and related disorders: Neuroendocrine, behavioral and cognitive implications -- Phyllis WISE (University of Washington, Seattle, USA) Estrogens: protective or risk factors in the injured brain .
Additional Edition:
ISBN 9783642337208
Additional Edition:
Buchausg. u.d.T. Multiple origins of sex differences in brain Berlin : Springer, 2013 ISBN 9783642337208
Additional Edition:
ISBN 3642337201
Language:
English
Keywords:
Neuroendokrinologie
;
Neuropsychologie
;
Neuropathologe
;
Geschlechtsunterschied
;
Konferenzschrift
DOI:
10.1007/978-3-642-33721-5
URL:
Volltext
(lizenzpflichtig)
Author information:
Christen, Yves 1948-
Author information:
Pfaff, Donald W. 1939-
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