Kooperativer Bibliotheksverbund

Berlin Brandenburg

and
and

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Humans
Type of Medium
Language
Year
  • 1
    Language: English
    In: Seminars in Pediatric Neurology, December 2013, Vol.20(4), pp.242-245
    Description: Our brain activity demonstrates amazing stability across multiple time frames ranging from a few milliseconds to several hours. The longer cycles are commonly called ultradian rhythms and they correspond to infralow frequencies (ILFs) in the milli-Hz range (0.001 Hz). Ultradian rhythms between 90 minutes and 2 hours or longer are readily observed in our electroencephalogram, and they reflect periods of activity and rest, cycles of cortical excitability and plasticity followed by relative inactivity. Our nightly sleep is organized into similar stages (rapid eye movement and non–rapid eye movement sleep) as is our daily behavior (ie, the basic rest-activity cycle). Astrocytes often exhibit milli-Hz ILFs, and they play a major role in shaping neuronal plasticity and activity, and thus may organize or influence the basic rhythms of sleep and waking. The nature and importance of astrocytes in human brain functioning is subsequently reviewed.
    Keywords: Medicine
    ISSN: 1071-9091
    E-ISSN: 1558-0776
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    In: Nature, 2012, Vol.492(7429), p.345
    Description: Rather than rely on the scientists to police themselves or wait for the US National Institutes of Health to dispatch safety guidelines, the mayor of Cambridge, Alfred Vellucci, convened public hearings on the topic. In the 1970s, biologists were not relied on to regulate matters of much broader concern on their own, despite their much-heralded initial efforts to self-govern. [...]the involvement of many other players did not quash scientific research and communication, but helped molecular biology and biotechnology to thrive. *
    Keywords: California ; United States–Us ; Espionage ; Classification ; Studies ; Life Sciences ; Avian Flu ; Biomedical Research ; Censorship ; Jurisdiction ; Deoxyribonucleic Acid–DNA ; Public Hearings ; World War II;
    ISSN: 0028-0836
    E-ISSN: 14764687
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Language: English
    In: Journal of Substance Abuse Treatment, January 2016, Vol.60, pp.21-26
    Description: Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a public health program used to identify, reduce, and prevent problematic use, abuse, and dependence on alcohol and illicit drugs that has been adapted for implementation in emergency departments and ambulatory clinics nationwide. This study used a combination of observational, timing, and descriptive analyses from a multisite evaluation to understand the workflow processes implemented in 21 treatment settings. Direct observations of 59 SBIRT practitioners and semi-structured interviews with 170 stakeholders, program administrators, practitioners, and program evaluators provided information about workflow in different medical care settings. The SBIRT workflow processes are presented at three levels: service delivery, information storage, and information sharing. Analyses suggest limited variation in the overall workflow processes across settings, although performance sites tailored the program to fit with existing clinical processes, health information technology, and patient characteristics. Strategies for successful integration include co-locating SBIRT providers in the medical care setting and integrating SBIRT data into electronic health records. Provisions within the Patient Protection and Affordable Care Act of 2010 call for the integration of behavioral health and medical care services. SBIRT is being adapted in different types of medical care settings, and the workflow processes are being adapted to ensure efficient delivery, illustrating the successful integration of behavioral health and medical care.
    Keywords: Sbirt ; Workflow ; Process ; Integration ; Emergency Department ; Ambulatory Clinic ; Social Welfare & Social Work
    ISSN: 0740-5472
    E-ISSN: 1873-6483
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    In: Addiction, February 2017, Vol.112, pp.82-91
    Description: Byline: Frances K. Del Boca, Thomas F. Babor, Jeremy W. Bray, Jesse Hinde, Jeremy Bray, David Kaiser, Erin Mallonee Keywords: Alcohol; financing; institutions; Medicaid; policy; SBIRT Abstract Aims To examine how institutional constraints, comprising federal actions and states' substance abuse policy environments, influence states' decisions to activate Medicaid reimbursement codes for screening and brief intervention for risky substance use in the United States. Methods A discrete-time duration model was used to estimate the effect of institutional constraints on the likelihood of activating the Medicaid reimbursement codes. Primary constraints included federal Screening, Brief Intervention and Referral to Treatment (SBIRT) grant funding, substance abuse priority, economic climate, political climate and interstate diffusion. Study data came from publicly available secondary data sources. Results Federal SBIRT grant funding did not affect significantly the likelihood of activation (P = 0.628). A $1 increase in per-capita block grant funding was associated with a 10-percentage point reduction in the likelihood of activation (P = 0.003) and a $1 increase in per-capita state substance use disorder expenditures was associated with a 2-percentage point increase in the likelihood of activation (P = 0.004). States with enacted parity laws (P = 0.016) and a Democratic-controlled state government were also more likely to activate the codes. Conclusion In the United States, the determinants of state activation of Medicaid Screening, Brief Intervention and Referral to Treatment (SBIRT) reimbursement codes are complex, and include more than financial considerations. Federal block grant funding is a strong disincentive to activating the SBIRT reimbursement codes, while more direct federal SBIRT grant funding has no detectable effects.
    Keywords: Alcohol ; Financing ; Institutions ; Medicaid ; Policy ; Sbirt
    ISSN: 0965-2140
    E-ISSN: 1360-0443
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Language: English
    In: Isis, March 2012, Vol.103(1), pp.126-138
    Description: Though the notion of a scientific textbook has been around for almost three centuries, the category has hardly been stable. The plasticity of the textbook genre may be illustrated by recent variations as well as long-term trends. In this brief essay I examine two idiosyncratic but highly successful physics books, each published in the mid 1970s, whose production, marketing, and adoption reveal some of the slippage between such categories as textbook, scholarly monograph, and popular best seller.
    Keywords: Focus: Textbooks in the Sciences
    ISSN: 00211753
    E-ISSN: 15456994
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Language: English
    In: Science of the total environment, 2013, Vol.450, pp.92-107
    Description: Global understanding of land–ocean nutrient fluxes increasingly recognizes the disproportionate importance of small rivers. We studied nutrient fluxes from a small catchment in fast developing southern China to uncover effects of land-use. Water was sampled in the macro-tidal estuary of Nanliu River and adjacent Lianzhou Bay in spring and summer of investigate spatial and temporal variations of dissolved nutrients. High riverine concentrations of nitrate (NO₃; up to 220μM) and phosphate (PO₄; up to 3.7μM) mainly originated from agricultural fertilizer input. Riverine dissolved silica (Si; up to 47μM) increased in the oligosaline part of the estuary through human disturbance of bottom sediments. Dissolved organic nitrogen (DON; up to 194μM) and ammonium (NH₄; up to 40μM) concentrations increased within the estuary due to inputs from livestock and mussel beds, respectively. Aquaculture ponds contained high concentrations of NH₄ (up to 355μM) and DON (up to 151μM) but are not an important source to the estuary due to rare wastewater discharge and low absolute nutrient amounts relative to river export. Nutrient concentrations in Lianzhou Bay were low because tidal currents disperse land-derived nutrients offshore into the adjacent Beibu Gulf. A high proportion of regenerated nitrogen in the bay suggests that primary production is sustained by rapid in situ nutrient cycling between primary producers and benthic consumers. High nutrient export makes the Nanliu River an important nutrient source for the north-western South China Sea, despite its proportionately small size. Macro-tide induced short-term concentration changes exceed variability on seasonal and sub-seasonal scales. All nutrients vary inter-annually and between seasons, depending on precipitation-driven river runoff. Total nutrient export to Beibu Gulf coastal waters is stronger during the high discharge period in summer and autumn. In recent years changing nitrogen to phosphorus ratios have alleviated phosphorus limitation in Lianzhou Bay, permitting increased primary productivity. ; p. 92-107.
    Keywords: Fertilizers ; Watersheds ; Trophic Relationships ; Spring ; Nitrogen ; Biogeochemical Cycles ; Estuaries ; Autumn ; Silica ; Sediments ; Dissolved Organic Nitrogen ; Nutrient Transport ; Seasonal Variation ; Mussels ; Nitrates ; Phosphorus ; Primary Productivity ; Humans ; Phosphates ; Rivers ; Nutrient Content ; Livestock ; Tides ; Nutrients ; Ponds ; Runoff ; Summer ; Coastal Water
    ISSN: 0048-9697
    Source: AGRIS (Food and Agriculture Organization of the United Nations)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Language: English
    In: Science of the Total Environment, 15 April 2013, Vol.450-451, pp.92-107
    Description: Global understanding of land–ocean nutrient fluxes increasingly recognizes the disproportionate importance of small rivers. We studied nutrient fluxes from a small catchment in fast developing southern China to uncover effects of land-use. Water was sampled in the macro-tidal estuary of Nanliu River and adjacent Lianzhou Bay in spring and summer of investigate spatial and temporal variations of dissolved nutrients. High riverine concentrations of nitrate (NO ; up to 220 μM) and phosphate (PO ; up to 3.7 μM) mainly originated from agricultural fertilizer input. Riverine dissolved silica (Si; up to 47 μM) increased in the oligosaline part of the estuary through human disturbance of bottom sediments. Dissolved organic nitrogen (DON; up to 194 μM) and ammonium (NH ; up to 40 μM) concentrations increased within the estuary due to inputs from livestock and mussel beds, respectively. Aquaculture ponds contained high concentrations of NH (up to 355 μM) and DON (up to 151 μM) but are not an important source to the estuary due to rare wastewater discharge and low absolute nutrient amounts relative to river export. Nutrient concentrations in Lianzhou Bay were low because tidal currents disperse land-derived nutrients offshore into the adjacent Beibu Gulf. A high proportion of regenerated nitrogen in the bay suggests that primary production is sustained by rapid in situ nutrient cycling between primary producers and benthic consumers. High nutrient export makes the Nanliu River an important nutrient source for the north-western South China Sea, despite its proportionately small size. Macro-tide induced short-term concentration changes exceed variability on seasonal and sub-seasonal scales. All nutrients vary inter-annually and between seasons, depending on precipitation-driven river runoff. Total nutrient export to Beibu Gulf coastal waters is stronger during the high discharge period in summer and autumn. In recent years changing nitrogen to phosphorus ratios have alleviated phosphorus limitation in Lianzhou Bay, permitting increased primary productivity. ► Small catchments supply high proportion of nutrients to north western South China Sea. ► Hinterland and offshore sources, not intensive aquaculture, dominate nitrogen input. ► Marcotides prevent near-shore eutrophication by dispersing human nutrient inputs. ► Long-term changes in nutrient delivery increased coastal productivity.
    Keywords: Macro-Tides ; Anthropogenic Impact ; Long-Term Trend ; Flushing ; Nutrient Pollution ; River Export ; Environmental Sciences ; Biology ; Public Health
    ISSN: 0048-9697
    E-ISSN: 1879-1026
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    In: Annals of the New York Academy of Sciences, December 2015, Vol.13611(1), pp.36-57
    Description: From the discovery of new galaxies and nearly undetectable dark energy to the quantum entanglement of particles across the universe, new findings in physics naturally elicit a sense of awe and wonder. For the founders of modern physics—from Einstein and Bohr to Heisenberg, Pauli, and Bohm—a fascination with deeper questions of meaning and ultimate reality led some of them to explore esoteric traditions and metaphysics. More recently, however, physicists have largely shunned such philosophical and spiritual associations. What can contemporary physics offer us in the quest to understand our place in the universe? Has physics in some ways become a religion unto itself that rejects the search for existential meaning? Discussion of these and related questions is presented in this paper.
    Keywords: Physics ; Metaphysics ; Dark Energy ; Matter
    ISSN: 0077-8923
    E-ISSN: 1749-6632
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Language: English
    In: Immunotherapy, February 2013, Vol.5(2), pp.121-30
    Description: Neovascular age-related macular degeneration (AMD) is the leading cause of legal blindness in patients over the age of 50 in the western world. Intravitreally administered anti-VEGF drugs have been developed to halt neovascular growth in AMD. Randomized trials have demonstrated the excellent safety profile and significant benefit of anti-VEGF therapy in maintaining vision. Aflibercept (Eylea(®); Regeneron, NY, USA) is a soluble decoy receptor against VEGF that offers greater potency and binding affinity than other anti-VEGF drugs. Having received US FDA approval for neovascular AMD in November 2011, aflibercept given every 8 weeks after a loading dose was 'clinically equivalent' and statistically noninferior to the current FDA-approved therapy ranibizumab (Lucentis(®); Genentech, CA, USA), given every 4 weeks. This article discusses the clinical background of AMD, development of aflibercept, results of the clinical trials and the future role of aflibercept in ocular neovascular diseases.
    Keywords: Macular Degeneration -- Drug Therapy ; Neovascularization, Pathologic -- Drug Therapy ; Receptors, Vascular Endothelial Growth Factor -- Therapeutic Use ; Recombinant Fusion Proteins -- Therapeutic Use
    ISSN: 1750743X
    E-ISSN: 1750-7448
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Language: English
    In: Canadian Journal of Public Health, 2018, Vol.109(1), pp.108-116
    Description: OBJECTIVESSince 2004, the Montreal heat response plan (MHRP) has been developed and implemented on the Island of Montreal to reduce heat-related health effects in the general population. In this paper, we aimed to assess the barriers and facilitators to implementation of the MHRP and evaluate the awareness of key elements of the plan by healthcare professionals and individuals from vulnerable populations. METHODSData were gathered from monitoring reports and a questionnaire administered to managers of healthcare institutions and healthcare workers in Montreal-area health and social services institutions. Individual interviews and focus groups with healthcare workers and with individuals with schizophrenia or suffering from drug or alcohol dependencies were performed. Data were categorized according to predefined subthemes. Coding matrices were then used to determine the most frequently occurring elements in the subthemes. RESULTSOur results indicate that actions are progressively implemented each year in the healthcare network. Intensification of surveillance for signs of heat-related illness is the most frequently reported measure. Identification and prioritization of clientele and homecare patients are identified as a challenge, as is ensuring the availability of sufficient personnel during a heat wave. Analysis of practice and awareness in healthcare professionals reveals that preventive measures are known and applied by the personnel. Individuals from vulnerable population groups were not uniformly aware of preventive measures, and consequently, variability was observed in their application. CONCLUSIONThe framework proposed in this study revealed valuable information that can be useful to improve plans aimed at reducing heat-related health effects in the population.
    Keywords: Extreme heat ; Environment ; Public health
    ISSN: 0008-4263
    E-ISSN: 1920-7476
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages