In:
European Pharmaceutical Journal, Walter de Gruyter GmbH, Vol. 64, No. 2 ( 2017-11-27), p. 9-14
Abstract:
Using small angle neutron diffraction and molecular dynamics simulations we studied the interactions between calcium (Ca 2+ ) or zinc (Zn 2+ ) cations, and oriented gel phase dipalmitoyl-phosphatidylcholine (DPPC) bilayers. For both cations studied at ~1:7 divalent metal ion to lipid molar ratio (Me 2+ :DPPC), bilayer thickness increased. Simulation results helped reveal subtle differences in the effects of the two cations on gel phase membranes.
Type of Medium:
Online Resource
ISSN:
2453-6725
DOI:
10.1515/afpuc-2016-0018
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2017
detail.hit.zdb_id:
2548376-6
detail.hit.zdb_id:
2935847-4
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