Kooperativer Bibliotheksverbund

Berlin Brandenburg

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  • 1
    Online Resource
    Online Resource
    Totowa, NJ : Humana Press
    Format: Online-Ressource (X, 162 p. 50 illus., 47 illus. in color) , digital
    Edition: Online-Ausg.] 2013 Springer eBook Collection. Medicine Recurso electronico; Disponible via World Wide Web
    ISBN: 9781627033671 , 9781627033664
    Series Statement: Current Clinical Urology
    Content: Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer
    Content: ​Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer. The book also addresses many of the novel diagnostic and therapeutic surgical approaches to inguinal lymph nodes, including dynamic sentinel node biopsy and minimally invasive surgery. The authors also discuss many of the clinical pearls and surgical considerations that can optimize treatment outcomes while minimizing the morbidity and inherent risk of complications in patients undergoing an open inguinal lymph node dissection. Lastly, the volume presents a discussion of the paradigm shift in the management of bulky inguinal lymph node metastases from penile cancer consisting of neoadjuvant systemic chemotherapy followed by consolidative surgical resection, which can offer an improved likelihood of survival as shown in a recent phase 3 clinical trial.      Penile Cancer: Diagnosis and Management will serve as a resource for clinicians and researchers seeking an overview on the current state of knowledge in penile cancer. The editor has gathered leading worldwide experts in this field who have written a very practical and useful textbook for clinicians in an attempt to optimize patient outcomes and promote the pivotal scientific advances made in recent years
    Note: Includes bibliographical references and index , Penile Cancer; Copyright; Foreword; Contents; Contributors; 1: Epidemiology and Risk Factors for Penile Cancer; Epidemiology; Risk Factors in the Pathogenesis of Penile Cancer; Human Papilloma Virus; Intracellular Activity of HPV; Presence of Foreskin; Phimosis; Infection; Hygiene; Zoophilia; PUVA Treatment; Socioeconomic Factors; Smoking; Premalignant Dermatoses; Preventative Strategies; Rationale for HPV Vaccination; Circumcision; Condom Use; Conclusion; References; 2: Staging and Risk Stratification in Penile Cancer; Staging Systems for Penile Cancer; Jackson Staging System , TNM/AJCC Staging SystemImaging Studies Useful for Staging Penile Cancer; Penile Imaging; Cavernosography; Sonography; Computed Tomography and Positron Emission Tomography; Magnetic Resonance Imaging; Intercavernosal Alprostadil; Endoluminal Coils; Inguinal Imaging; Cross-sectional Imaging; PET/CT; Lymphotropic Nanoparticle Enhanced MRI; Dynamic Sentinel Lymph Node Biopsy; Systemic Imaging; Penile Cancer Prognosis; Population Survival Estimates; Survival Probability; Relative Survival; Case Fatality Ratio; Patient-Related Prognostic Factors; Age; Multimorbidity , Tumor-Related Prognostic FactorsDegree of Local Invasion (T Stage); Tumor Depth (Thickness); Lymph Node Metastasis (N Stage); Lymphovascular Invasion; Perineural Invasion; Distant Organ Metastases (M Stage); Tumor Grade; Tumor Location on Penis; Histologic Subtype; Human Papilloma Virus; Molecular Markers; Comprehensive Prognostic Tools in Penile Cancer; Solsona and European Association of Urology (EAU) Risk Groups; Gruppo Uro-Oncologico del Nord Est (GUONE) Nomogram; Zini Risk Groups; Thuret Nomogram; Conclusion; References; 3: Pathology of Penile Cancer and Its Precursor Lesions , Anatomy and Histology of the PenisPremalignant Lesions of the Penis; Squamous Cell Carcinoma of the Penis; Patterns of Growth of Penile Squamous Cell Carcinoma; Morphologic Types of Penile Squamous Cell Carcinoma; Squamous Cell Carcinoma (Usual Type); Papillary Carcinoma, Not Otherwise Specified; Warty (Condylomatous) Carcinoma; Verrucous Carcinoma; Basaloid Carcinoma; Squamous Cell Carcinoma with Sarcomatoid Dedifferentiation; Other Squamous Carcinoma Types; Pathology Reporting and Predictive Pathology Features in Penile Squamous Cell Carcinoma , Pathologic Reporting of Penile Squamous Cell CarcinomaHistologic Subtype of Primary Tumor; Tumor Grade; Extent of Invasion and TNM Pathologic Stage; Lymphovascular Invasion; Perineural Invasion; Role of Human Papilloma Virus in Penile Squamous Cell Carcinoma; Other Tumors of the Penis; Conclusion; References; 4: Evolving Imaging Modalities in the Diagnosis and Staging of Penile Cancer; Introduction; Staging of the Primary Tumor; Physical Examination; Imaging for Staging of Primary Tumor; Ultrasound; Magnetic Resonance Imaging; Staging of the Regional Lymph Nodes; Physical Examination , Pathologic Features of the Primary Tumor as a Predictor of Regional Lymph Node Involvement , 1. Epidemiology and Risk Factors for Penile Cancer -- 2. Staging and Risk Stratification in Penile Cancer -- 3. Pathology of Penile Cancer and Its Precursor Lesions -- 4. Evolving Imaging Modalities in the Diagnosis and Staging of Penile Cancer -- 5. Penile-Sparing Approaches to Primary Penile Tumors -- 6. Surgical Concepts and Considerations of Inguinal Lymph Node Dissection for Penile Cancer -- 7. Minimally Invasive Surgical Approaches to Penile Cancer -- 8. Applications of Radiation Therapy in the Management of Penile Cancer -- 9. Multimodal Approach to the Management of Locally Advanced and Metastatic Penile Cancer -- 10. New Horizons in the Diagnosis, Treatment, and Prevention of Penile Cancer. , Recurso electronico; Disponible via World Wide Web
    Additional Edition: Print version Penile Cancer
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Peniskrebs
    URL: Volltext  (Lizenzpflichtig)
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  • 2
    Online Resource
    Online Resource
    Hauppauge, N.Y : Nova Biomedical
    Format: Online-Ressource (2 v) , ill
    Edition: Online-Ausg.]
    ISBN: 1620816490 , 9781620816493 , 1620814943
    Series Statement: Nephrology research and clinical developments
    Note: Description based upon print version of record
    Additional Edition: Print version Essentials and updates in urologic oncology
    Language: English
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  • 3
    Online Resource
    Online Resource
    Philadelphia : Elsevier Health Sciences
    Format: 1 Online-Ressource (169 p)
    ISBN: 9780323476966 , 9780323477154
    Series Statement: The Clinics: Surgery v.43-4
    Content: The Editor has assembled top experts to write authoritative reviews on the latest advances in the diagnosis and treatment of penile, urethral, and scrotal cancers. The issue stresses contrasting approaches and includes articles devoted to the following topics: radiation in primary urethral cancers; the role of node dissection; role of HPV in penile pre-neoplastic and carcinogenesis; advances in penile-sparing surgical approaches in the management of primary penile tumors; minimally invasive approaches to evaluating inguinal nodes in penile cancer patients; multimodal therapy in the management of advanced penile cancer; management of urethral cancer recurrences; Preneoplastic and primary scrotal cancer; and Advances in surgical reconstructive techniques in the management of penile, urethral, and scrotal cancer. The state-of-the article clinical and surgical details in this issue will keep urologists and other healthcare professionals current on the clinical management of these cancers.
    Note: Description based upon print version of record
    Additional Edition: Print version Spiess, Philippe E Penile, Urethral, and Scrotal Cancer, An Issue of Urologic Clinics of North America
    Language: English
    Keywords: Electronic books
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  • 4
    Online Resource
    Online Resource
    New York, NY : Humana Press
    Format: Online-Ressource (XII, 151 p. 61 illus., 46 illus. in color, online resource)
    Edition: 2nd ed. 2017
    ISBN: 9781493966790 , 9781493966776
    Series Statement: Current Clinical Urology
    Content: This fully updated and revised second edition address specifically some of the significant advances made in our understanding of the pathophysiology of penile cancer including discussion of the suspected role of the human papilloma virus in penile carcinogenesis. Similarly, the molecular pathways implicated in precancerous and penile cancer will be discussed as these are the present targets of novel therapeutic approaches to this disease. The text details the recent national and international diagnostic and treatment guidelines that have been developed by both the National Comprehensive Cancer Network© and the European Urological Association establishing evidence based standards upon which the care of penile cancer should be based. The text also covers significant advances made in the diagnostic and therapeutic approach to both primary tumors and inguinal nodal metastases resulting from penile cancer such as penile sparing surgery and minimally invasive inguinal lymph node surgery. The text will similarly highlights the improvement in cancer specific outcome in the management of loco-regionally advanced (N2/3) penile cancer managed by upfront systemic chemotherapy followed by consolidative surgery in appropriately selected patients based on recent prospective phase II data. It also covers the role of radiotherapy in the management of penile cancer for both primary tumors and/or at sites of regional or distant metastases. Finally, some of the novel systemic approaches being devised in the management of advanced penile cancer along with some upcoming international trials soon to be opened which likely will re-define the present therapeutic approaches to penile cancer are discussed. The Second Edition of Penile Cancer: Diagnosis and Treatment will constitute a comprehensive review of the above mentioned subjects in addition to a few select topics of high clinical relevance, with the readership predominantly consisting of urologists, medical and surgical oncologists, and other healthcare professionals
    Content: Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions -- Diagnostic Tools in the Evaluation and Management of Penile Cancer -- Penile-Sparing Surgical Approaches in the Management of Primary Penile Tumours -- Dynamic Sentinel Node Biopsy and FDG-PET/CT for Lymph Node Staging in Penile Cancer -- Surgical Decision Making, Technical Considerations and Clinical Pearls in Therapeutic Inguinal Node Dissection Surgery for Penile Cancer -- Minimally Invasive Surgical Approaches to Inguinal Nodes in the Absence of Palpable Adenopathy -- Pelvic Lymph Node Dissection for Penile Cancer: Answering the Conundrum of When and How It Should Be Conducted -- Multmodal Approach to Locally Advanced and Metastatic Penile Cancer -- The Role of Radiotherapy in the Management of Penile Cancer
    Additional Edition: Druckausg.
    Additional Edition: Printed edition
    Language: English
    Keywords: Peniskrebs
    URL: Volltext  (Lizenzpflichtig)
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  • 5
    Online Resource
    Online Resource
    Totowa, NJ : Humana Press
    Format: Online-Ressource (X, 162 p. 50 illus., 47 illus. in color, digital)
    ISBN: 9781627033671 , 9781627033664
    Series Statement: Current Clinical Urology
    Additional Edition: Buchausg. u.d.T. Penile cancer
    Language: English
    Keywords: Peniskrebs ; Aufsatzsammlung
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  • 6
    Book
    Book
    New York [u.a.] : Humana Press
    Format: X, 162 S. , Ill., graph. Darst.
    ISBN: 9781627033664 , 9781627033671
    Series Statement: Current clinical urology
    Additional Edition: Online-Ausg. Spiess, Philippe E. Penile Cancer
    Language: English
    Keywords: Peniskrebs ; Aufsatzsammlung
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  • 7
    Online Resource
    Online Resource
    New York, NY : Springer New York
    Format: 1 Online-Ressource (155 p)
    Edition: 2nd ed
    ISBN: 9781493966790 , 9781493966776
    Series Statement: Current Clinical Urology
    Content: Preface -- Contents -- Abbreviations -- Contributors -- 1: Understanding the Pathophysiology of Penile Cancer and Its Preneoplastic Lesions -- Epidemiology of Penile Cancer -- Risk Factors for Penile Carcinoma -- Pathophysiology -- Human Papillomavirus -- HPV-Mediated Pathway -- HPV-Independent Pathway -- Penile Cancer Precursor Lesions -- Condyloma Acuminatum -- Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor) -- Bowenoid Papulosis -- Lichen Sclerosus (Balanitis Xerotica Obliterans) -- Carcinoma In Situ (Erythroplasia of Queyrat and Bowen's Disease) -- Histologic Subtypes
    Content: Conclusions -- References -- 2: Diagnostic Tools in the Evaluation and Management of Penile Cancer -- Introduction -- Novel Image-Based Diagnostic Tools -- Evaluation and Management of the Primary Penile Lesion -- Evaluation and Management of Loco-Regional Metastatic Lymphatic Spread -- Penile Cancer Biomarkers -- p53 -- p16INK4a -- Ki-67 -- Proliferating Cell Nuclear Antigen -- C-Reactive Protein -- Cyclin D1 -- Other Biomarkers -- Conclusions -- References -- 3: Penile-Sparing Surgical Approaches in the Management of Primary Penile Tumours -- Introduction -- Basis for Penile-Preserving Surgery
    Content: Topical Therapies -- Suitable for Stage Tis Disease Only -- 5 % 5-Fluorouracil (5-FU) -- Imiquimod -- Laser Therapy -- For Stage Tis, But Has Been Used Up to Stage T2 Lesions -- Penile-Sparing Surgical Techniques -- Circumcision -- For Lesions Confined to the Prepuce -- Total Glans Resurfacing -- For Glanular Tis/Ta and Up to Stage T1a Disease -- Partial Glans Resurfacing -- For Isolated Foci of Tis/Ta Affecting 〈 50 % of Glans -- Moh's Micrographic Surgery -- For Stage T1a, But Has Been Used Up to Stage T3 -- Wide Local Excision/Partial Glansectomy
    Content: For Small, Discrete Lesions on the Glans Up to Stage T1a -- Glansectomy and Reconstruction -- For Stage T1b/T2 Tumours Confined to the Glans -- Distal Corporectomy/Partial Penectomy and Reconstruction -- For Stage T2b/Distal T3 Disease -- Conclusions -- References -- 4: Dynamic Sentinel Node Biopsy and FDG-­PET/CT for Lymph Node Staging in Penile Cancer -- Introduction -- Risk-Adapted Approach -- Dynamic Sentinel Node Biopsy -- FDG-PET/CT -- Conclusion -- References
    Content: 5: Surgical Decision-Making, Technical Considerations, and Clinical Pearls in Therapeutic Inguinal Node Dissection for Penile Cancer -- Surgical Decision-Making in Patients with CN +ve Penile Cancer -- Unresectable Inguinal Lymphadenopathy -- Role of Systemic Therapy in High-Volume Lymph Node Metastasis -- Technical Considerations Among Patients Undergoing Lymphadenectomy for Clinically Positive Nodes -- Initial Resection of Clinically Mobile Nodes Less Than 4 cm with No Overlying Skin Fixation -- Perioperative Care -- Patient Position -- Skin Incision -- Surgical Boundaries
    Content: Clinically Node Positive Inguinal Field
    Note: Description based upon print version of record
    Additional Edition: Print version Spiess, Philippe E Penile Cancer : Diagnosis and Treatment
    Language: English
    Keywords: Electronic books
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  • 8
    Book
    Book
    Philadelphia, Pennsylvania : Elsevier
    Format: xviii Seiten, Seite 419-566 , Illustrationen, Diagramme
    ISBN: 9780323476966
    Series Statement: Urologic clinics of North America volume 43, number 4 (November 2016)
    Language: English
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  • 9
    Online Resource
    Online Resource
    New York, NY : Springer New York
    Format: 1 Online Ressource (XII, 151 p. 61 illus., 46 illus. in color)
    Edition: 2nd ed.
    ISBN: 9781493966790 , 9781493966776
    Series Statement: Current Clinical Urology
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Peniskrebs
    URL: Volltext  (URL des Erstveröffentlichers)
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  • 10
    Book
    Book
    New York, NY : Humana Press
    Format: 1 Online-Ressource (xii, 151 Seiten) , Illustrationen, Diagramme
    Edition: Second edition
    ISBN: 9781493966790 , 9781493966776
    Series Statement: Current clinical urology
    Additional Edition: Erscheint auch als
    Language: English
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