Format:
Online-Ressource (x, 267 p)
,
ill
,
26 cm
Edition:
2nd ed
Edition:
Online-Ausg. Palo Alto, Calif ebrary 2009 Electronic reproduction; Available via World Wide Web
ISBN:
0470185902
,
9780470185902
Content:
A comprehensive and approachable introduction to crystallography - now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diff
Note:
Includes bibliographical references (p. 238-242) and index
,
INTRODUCTION TO MACROMOLECULAR CRYSTALLOGRAPHY; CONTENTS; PREFACE; 1 AN OVERVIEW OF MACROMOLECULAR CRYSTALLOGRAPHY; What Do We Mean by the Structure of Something?; An Analogy; A Lens and Optical Diffraction Patterns; How X-Ray Diffraction Works; The Phase Problem; The Electron Density; 2 CRYSTALLIZATION OF MACROMOLECULES; Crystals Grow from Supersaturated Solutions; Why Crystals Grow; Proteins Present Special Problems for Crystallographers; Properties of Macromolecular Crystals; Crystallization Strategy; Screening and Optimization; Creating the Supersaturated State; Precipitating Agents
,
Factors Influencing Protein Crystal GrowthSome Useful Considerations; Typical Trial Arrays; The Importance of Protein Purity and Homogeneity; Solubilization; Seeding; Automated Crystallization and Robotics; Important Principles; 3 THE NATURE OF CRYSTALS: SYMMETRY AND THE UNIT CELL; The Asymmetric Unit; The Space Group; The Unit Cell; The Lattice Translations; Symmetry and Equivalent Positions; Why So Few Kinds of Unit Cells; Primitive and Centered Lattices; Planes, Miller Indexes, and Convolutions; The Reciprocal Lattice; Crystals as Waves of Electrons in Three-Dimensional Space
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4 WAVES AND THEIR PROPERTIESThe Properties of Waves; Waves as Vectors and Complex Numbers; Addition of Waves; Manipulating Vectors; Some Useful Wave Relationships; The Fourier Synthesis, Planes, and the Electron Density; 5 DIFFRACTION FROM POINTS, PLANES, MOLECULES, AND CRYSTALS; Diffraction Pattern of an Arbitrary Array of Points in Space; Diffraction from Equally Spaced Points Along a Line; Diffraction from a Plane, Families of Planes, and Lattices of Points; Continuous and Discontinuous Transforms; Diffraction from a Crystal; The Structure Factor for a Crystal
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The Structure Factor as a Product of TransformsTemperature Factors; Centers of Symmetry; Friedel's Law; Anomalous Dispersion Effects; The Electron Density Equation; The Phase Problem; 6 INTERPRETATION OF DIFFRACTION PATTERNS; Diffraction Patterns, Planes, and Reciprocal Space; Ewald's Sphere; Crystal Symmetry and the Symmetry of the Diffraction Pattern; Symmetry and Systematic Absences; Analysis of Diffraction Patterns; Symmetry in Diffraction Space; More Thoughts on Space Groups; Other Information in Diffraction Patterns; 7 DATA COLLECTION; What is Involved
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X-ray Sources and the Production of X RaysDetectors and the Recording of Diffraction Intensities; Data Management Procedures; Crystal Mounting and Handling; X-ray Data Processing; Scaling of X-ray Diffraction Data; Real Space and Diffraction Space; 8 SOLVING THE PHASE PROBLEM; Patterson Methods; The Heavy Atom Method; The R Factor and Crystallographic Refinement; Isomorphous Replacement; Formulation of Isomorphous Replacement in Protein Crystallography; Isomorphous Replacement in Practice; Molecular Replacement; Phase Extension Using Noncrystallographic Symmetry
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Anomalous Scattering Approaches
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Electronic reproduction; Available via World Wide Web
Additional Edition:
0470391510
Additional Edition:
0470391545
Additional Edition:
9780470391518
Additional Edition:
9780470391549
Additional Edition:
Print version Introduction to Macromolecular Crystallography
Language:
English
Subjects:
Physics
Keywords:
Kristallographie
;
Makromolekül
;
Röntgenkristallographie
;
Kristallsymmetrie
DOI:
10.1002/9780470391518
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