Format:
1 online resource (890 pages)
Edition:
5th ed.
ISBN:
9781555819286
Series Statement:
ASM Bks.
Content:
Presents a compilation of bacterial virulence strategies and cutting-edge therapies that have been unraveled in recent years. Serves as a textbook for graduate courses on bacterial pathogenesis. Also a useful resourse for veterinary scientists, food microbiologists, and other established researchers interested in pathogenesis.
Content:
Cover -- Half-Title Page -- Title Page -- Copyright Page -- Contents -- Contributors -- Preface -- Acknowledgments -- I: BACTERIAL-HOST INTERFACE -- 1. Evolution of Bacterial Pathogens Within the Human Host -- INTRODUCTION -- ANTAGONISTIC PLEIOTROPY AND THE FITNESS COST-BENEFIT ANALYSIS -- THE IMPACT OF HOST-PATHOGEN INTERACTIONS ON MICROBIAL EVOLUTION -- Host Selective Pressures: The Innate and Adaptive Immune Systems -- Host Selective Pressures: Antibiotic Resistance -- Microbial Competition -- CONCLUDING REMARKS -- ACKNOWLEDGMENTS -- CITATION -- REFERENCES -- 2. Bacterial Metabolism Shapes the Host-Pathogen Interface -- THE INTERFACE BETWEEN TWO ORGANISMS IS SHAPED BY METABOLIC INTERACTIONS -- BACTERIAL ENERGY METABOLISM DURING INFECTION -- What's for Dinner Inside the Host? -- The Host Is a Crowded and Sometimes Bountiful Place -- The Parts that Make It All Go -- The End of the Line: Using a Novel Electron Sink to Outpace the Competitors -- ION AND NUTRIENT ACQUISITION BY BACTERIAL PATHOGENS -- Transition Metal Ions: Precious Metals for Life -- Nutrient Acquisition -- METABOLIC CONTROL OF HOST-PATHOGEN INTERACTIONS -- Orienteering: Nutrient Sensors Control Metabolism and Niche Adaptations -- Evading Immune System Predation -- CONCLUSION -- ACKNOWLEDGMENTS -- CITATION -- REFERENCES -- 3. Iron Acquisition Strategies of Bacterial Pathogens -- BIOLOGICAL IMPORTANCE OF IRON -- IRON METABOLISM IN HEALTH AND DISEASE -- Host Iron Homeostasis -- Iron-Withholding as a Facet of Innate Immunity -- Hereditary Diseases Compromising Iron-Withholding Within the Host -- OVERVIEW OF BACTERIAL IRON ACQUISITION STRATEGIES -- Coordinated Regulation of Iron Acquisition and Virulence Gene Expression -- ACCESSING HEME IRON -- Extracellular Mechanisms of Heme Capture -- Heme Capture at the Cell Surface.
Note:
Description based on publisher supplied metadata and other sources
,
Preface ; Acknowledgments ; Chapter 1 : Evolution of Bacterial Pathogens Within the Human Host
,
Chapter 2 : Bacterial Metabolism Shapes the Host-Pathogen Interface
,
Chapter 3 : Iron Acquisition Strategies of Bacterial Pathogens
,
Chapter 4 : Sociomicrobiology and Pathogenic Bacteria
,
Chapter 5 : Candida-Bacteria Interactions: Their Impact on Human Disease
,
Chapter 6 : Microbial Endocrinology in the Pathogenesis of Infectious Disease
,
Chapter 7 : Small RNAs in Bacterial Virulence and Communication
,
Chapter 8 : Bacterial Secretion Systems: An Overview
,
Chapter 9 : The Structure and Function of Type III Secretion Systems
,
Chapter 10 : Mechanism and Function of Type IV Secretion During Infection of the Human Host
,
Chapter 11 : Type V Secretion Systems in Bacteria
,
Chapter 12 : The Versatile Type VI Secretion System
,
Chapter 13 : Type VII Secretion: A Highly Versatile Secretion System
,
Chapter 14 : Stress Responses, Adaptation, and Virulence of Bacterial Pathogens During Host Gastrointestinal Colonization
,
Chapter 15 : Bacterial Evasion of Host Antimicrobial Peptide Defenses
,
Chapter 16 : Antigenic Variation in Bacterial Pathogens
,
Chapter 17 : Mechanisms of Antibiotic Resistance
,
Chapter 18 : Chronic Bacterial Pathogens: Mechanisms of Persistence
,
Chapter 19 : The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response
,
Chapter 20 : Surviving Between Hosts: Sporulation and Transmission
,
Chapter 21 : Staying Alive: Vibrio cholerae's Cycle of Environmental Survival, Transmission, and Dissemination
,
Chapter 22 : Hijacking and Use of Host Lipids by Intracellular Pathogens
,
Chapter 23 : Contrasting Lifestyles Within the Host Cell
,
Chapter 24 : Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms
,
Chapter 25 : Cellular Exit Strategies of Intracellular Bacteria
,
Chapter 26 : Novel Targets of Antimicrobial Therapies
,
Chapter 27 : Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections
,
Chapter 28 : The Role of Biotin in Bacterial Physiology and Virulence: a Novel Antibiotic Target for Mycobacterium tuberculosis
,
Chapter 29 : Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases
,
Index.
Additional Edition:
9781555819279
Additional Edition:
Erscheint auch als Druck-Ausgabe 9781555819279
Language:
English
Bookmarklink