Format:
1 online resource (206 pages)
ISBN:
9781493915019
Content:
Upper Tract Urothelial Carcinoma represents the first book of its kind to be dedicated solely to UTUC. It's aim is to improve understanding and eventually care of a disease that is greatly understudied and underappreciated, yet commonly dealt with by many medical and urologic oncologists. The volume features new data regarding genetic susceptibility, gene expression studies and causative factors; contemporary concepts and controversies regarding diagnosis and staging of UTUC; prediction tools and their value in treatment decisions within each disease stage and patient selection and treatment options such as endoscopic management, distal ureterectomy, radical nephroureterectomy and chemotherapy. Up-to-date information regarding boundaries of surgical resection, indication and extent of lymphadenectomy is covered as well as the role of perioperative/neoadjuvant chemotherapy in patients with high-risk UTUC. Upper Tract Urothelial Carcinoma will be of great value to all Urologists, Medical Oncologists and fellows in Urologic Oncology as well as upper level residents in training in Urology and Medical Oncology.
Content:
Intro -- Preface -- Contents -- Contributors -- Chapter 1: Epidemiology and Risk Factors for Upper Urinary Urothelial Cancers -- Disease Demographics: Clues to Etiology -- Genetic Factors in Upper Tract Urothelial Carcinogenesis -- Hereditary Upper Tract Urothelial Cell Carcinoma -- High Penetrance Genetic Events -- Lynch Syndrome -- Tumor Spectrum Within Lynch Syndrome -- Detecting Lynch Syndrome -- Clinical Implications of Loss of Mismatch Repair -- Implications for Sporadic Upper Tract Urothelial Carcinoma -- Low Penetrance Genetic Events -- Detoxification Pathways -- Genome-Wide SNP Analysis in UC -- Acquired Exposures and Upper Tract Urothelial Carcinogenesis -- Exposures Shared by Urothelial Carcinoma in the Bladder and Upper Tracts -- Cigarette Smoking -- Occupational Carcinogen Exposure -- Acquired Exposures more Specific to UTUC -- Aristolochic Acid -- Chinese Herbs Nephropathy in Belgium -- Balkan Endemic Nephropathy -- Herbal Medicine Use in Taiwan -- Global Prevalence of AA-Induced UTUC -- Phenacetin and Analgesic Nephropathy -- Previous Urothelial Cancer in the Bladder or Contralateral Upper Tract -- Risk Over Time -- Prognostic Risk Factors for Upper Tract Recurrence -- Tumor Grade at Cystectomy -- Tumor Stage at Radical Cystectomy -- Carcinoma In Situ -- Recurrent UCB and Focality -- Ureteral Margin and Frozen Section Analysis -- History of UTUC -- Upper Tract Surveillance -- Who to Screen for UTUC After UCB -- How to Screen for UTUC After UCB -- Executive Summary -- References -- Chapter 2: Diagnosis and Evaluation of Upper Tract Urothelial Carcinoma (UTUC) -- Introduction -- Elements of Diagnosis -- Clinical Revelation -- Hematuria -- Pain -- Other Clinical Signs -- Asymptomatic Patients -- Imaging -- CT Urography -- MR Urography -- Endoscopy -- Retrograde Ureteropyelography -- Flexible Ureteroscopy and In Situ Biopsies.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
9781493915002
Additional Edition:
Erscheint auch als Druck-Ausgabe 9781493915002
Language:
English
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