Format:
VIII, 520 S.
,
Ill., graph. Darst.
,
235 mm x 155 mm
ISBN:
3642451055
,
3642451055
,
9783642451058
Series Statement:
Handbook of experimental pharmacology 220
Content:
This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington's syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles. --
Content:
This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington's syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles. --
Note:
Literaturangaben
,
The neurotrophin familyNGF, BDNF, NT3, and NT4 / M. Bothwell -- Deciphering proneurotrophin actions / B.L. Hempstead -- Spatiotemporal intracellular dynamics of neurotrophin and its receptors: implications for neurotrophin signaling and neuronal function / F.C. Bronfman, O.M. Lazo, C. Flores, and C.A. Escudero -- Neurotrophins: transcription and translation / A.E. West, P. Pruunsild, and T. Timmusk -- Neurotrophin receptors -- Trk receptors / Katrin Deinhardt and Moses V. Chao -- The biological functions and signaling mechanisms of the p75 neurotrophin receptor / B.R. Kraemer, S.O. Yoon, and B.D. Carter -- Sortilins in neurotrophic factor signaling / S. Glerup, A. Nykjaer, and C.B. Vaegter -- The biology of neurotrophins -- Neurotrophins in the regulation of cellular survival and death / Claire Ceni, Nicolas Unsain, Michele P. Zeinieh, and Philip A. Barker -- BDNF and synaptic plasticity, cognitive function, and dysfunction / B. Lu, G. Nagappan, and Y. Lu -- Nerve growth factor and nociception: from experimental embryology to new analgesic therapy / Gary R. Lewin, Stefan G. Lechner, and Ewan St. John Smith -- Neurotrophins and the regulation of energy balance and body weight / M. Rios -- The biology of neurotrophins: cardiovascular function / Costanza Emanueli, Marco Meloni, Wohaib Hasan, and Beth A. Habecker -- Neurotrophin signalling and transcription programmes interactions in the development of somatosensory neurons / F. Marmigère and P. Carroll -- Neurotrophins in pathological conditions -- Huntington's disease / Chiara Zuccato and Elena Cattaneo -- Motoneuron disease / M. Sendtner -- Neurotrophic factors in spinal cord injury / Vanessa S. Boyce and Lorne M. Mendell -- Neurotrophins and psychiatric disorders / E. Castrén -- Brain-derived neurotrophic factor and Rett syndrome / D.M. Katz -- Modulation of neurotrophin signaling by monoclonal antibodies / A. Rosenthal and J.C. Lin.
Additional Edition:
9783642451065
Language:
English
Keywords:
Neurotropher Faktor
;
Nervensystem
;
Krankheit
;
Pathophysiologie
;
Neurogenese
;
Therapie
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