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Content:
The mitochondria of yeast Saccharomyces cerevisiae contains more than 1000 proteins, majority of which are imported from the cytosol. The TIM23 and the TIM22 complexes in the inner mitochondrial membrane are essential transport systems for proper insertion of inner membrane and matrix proteins in mitochondria. Additionally, both complexes recognise different targeting signals on a precursor protein. In this study, the TIM23 and the TIM22 complexes were investigated regarding their structure and substrate spectrum respectively. The TOM and the TIM23 complexes cooperate for importing preseque...
Note:
Dissertation Georg-August-Universität Göttingen 2018
Additional Edition:
Erscheint auch als Druck-Ausgabe Gomkale, Ridhima Insights into mitochondrial presequence and carrier import pathways Göttingen, 2020
Language:
English
Keywords:
Hochschulschrift
URN:
urn:nbn:de:gbv:7-21.11130/00-1735-0000-0005-14B8-5-3
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URL:
https://d-nb.info/1220080691/34
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