Format:
Online-Ressource (X, 162 p. 50 illus., 47 illus. in color, digital)
ISBN:
9781627033671
Series Statement:
Current Clinical Urology
Content:
Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer
Content:
Penile Cancer: Diagnosis and Management provides a comprehensive overview of penile cancer for medical and surgical urologists oncologists, and other healthcare professionals. This book highlights many of the significant advances made in this field, which include a discussion of penile-sparing surgical and radiotherapeutic approaches to select primary penile tumors typically of lower stage and grade as well as advances in our understanding of the epidemiology, risk factors, and pathophysiology of penile cancer. The book also addresses many of the novel diagnostic and therapeutic surgical approaches to inguinal lymph nodes, including dynamic sentinel node biopsy and minimally invasive surgery. The authors also discuss many of the clinical pearls and surgical considerations that can optimize treatment outcomes while minimizing the morbidity and inherent risk of complications in patients undergoing an open inguinal lymph node dissection. Lastly, the volume presents a discussion of the paradigm shift in the management of bulky inguinal lymph node metastases from penile cancer consisting of neoadjuvant systemic chemotherapy followed by consolidative surgical resection, which can offer an improved likelihood of survival as shown in a recent phase 3 clinical trial. Penile Cancer: Diagnosis and Management will serve as a resource for clinicians and researchers seeking an overview on the current state of knowledge in penile cancer. The editor has gathered leading worldwide experts in this field who have written a very practical and useful textbook for clinicians in an attempt to optimize patient outcomes and promote the pivotal scientific advances made in recent years
Note:
Includes bibliographical references and index
,
Penile Cancer; Copyright; Foreword; Contents; Contributors; 1: Epidemiology and Risk Factors for Penile Cancer; Epidemiology; Risk Factors in the Pathogenesis of Penile Cancer; Human Papilloma Virus; Intracellular Activity of HPV; Presence of Foreskin; Phimosis; Infection; Hygiene; Zoophilia; PUVA Treatment; Socioeconomic Factors; Smoking; Premalignant Dermatoses; Preventative Strategies; Rationale for HPV Vaccination; Circumcision; Condom Use; Conclusion; References; 2: Staging and Risk Stratification in Penile Cancer; Staging Systems for Penile Cancer; Jackson Staging System
,
TNM/AJCC Staging SystemImaging Studies Useful for Staging Penile Cancer; Penile Imaging; Cavernosography; Sonography; Computed Tomography and Positron Emission Tomography; Magnetic Resonance Imaging; Intercavernosal Alprostadil; Endoluminal Coils; Inguinal Imaging; Cross-sectional Imaging; PET/CT; Lymphotropic Nanoparticle Enhanced MRI; Dynamic Sentinel Lymph Node Biopsy; Systemic Imaging; Penile Cancer Prognosis; Population Survival Estimates; Survival Probability; Relative Survival; Case Fatality Ratio; Patient-Related Prognostic Factors; Age; Multimorbidity
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Tumor-Related Prognostic FactorsDegree of Local Invasion (T Stage); Tumor Depth (Thickness); Lymph Node Metastasis (N Stage); Lymphovascular Invasion; Perineural Invasion; Distant Organ Metastases (M Stage); Tumor Grade; Tumor Location on Penis; Histologic Subtype; Human Papilloma Virus; Molecular Markers; Comprehensive Prognostic Tools in Penile Cancer; Solsona and European Association of Urology (EAU) Risk Groups; Gruppo Uro-Oncologico del Nord Est (GUONE) Nomogram; Zini Risk Groups; Thuret Nomogram; Conclusion; References; 3: Pathology of Penile Cancer and Its Precursor Lesions
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Anatomy and Histology of the PenisPremalignant Lesions of the Penis; Squamous Cell Carcinoma of the Penis; Patterns of Growth of Penile Squamous Cell Carcinoma; Morphologic Types of Penile Squamous Cell Carcinoma; Squamous Cell Carcinoma (Usual Type); Papillary Carcinoma, Not Otherwise Specified; Warty (Condylomatous) Carcinoma; Verrucous Carcinoma; Basaloid Carcinoma; Squamous Cell Carcinoma with Sarcomatoid Dedifferentiation; Other Squamous Carcinoma Types; Pathology Reporting and Predictive Pathology Features in Penile Squamous Cell Carcinoma
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Pathologic Reporting of Penile Squamous Cell CarcinomaHistologic Subtype of Primary Tumor; Tumor Grade; Extent of Invasion and TNM Pathologic Stage; Lymphovascular Invasion; Perineural Invasion; Role of Human Papilloma Virus in Penile Squamous Cell Carcinoma; Other Tumors of the Penis; Conclusion; References; 4: Evolving Imaging Modalities in the Diagnosis and Staging of Penile Cancer; Introduction; Staging of the Primary Tumor; Physical Examination; Imaging for Staging of Primary Tumor; Ultrasound; Magnetic Resonance Imaging; Staging of the Regional Lymph Nodes; Physical Examination
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Pathologic Features of the Primary Tumor as a Predictor of Regional Lymph Node Involvement
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1. Epidemiology and Risk Factors for Penile Cancer -- 2. Staging and Risk Stratification in Penile Cancer -- 3. Pathology of Penile Cancer and Its Precursor Lesions -- 4. Evolving Imaging Modalities in the Diagnosis and Staging of Penile Cancer -- 5. Penile-Sparing Approaches to Primary Penile Tumors -- 6. Surgical Concepts and Considerations of Inguinal Lymph Node Dissection for Penile Cancer -- 7. Minimally Invasive Surgical Approaches to Penile Cancer -- 8. Applications of Radiation Therapy in the Management of Penile Cancer -- 9. Multimodal Approach to the Management of Locally Advanced and Metastatic Penile Cancer -- 10. New Horizons in the Diagnosis, Treatment, and Prevention of Penile Cancer.
Additional Edition:
9781627033664
Additional Edition:
Buchausg. u.d.T. Penile cancer New York [u.a.] : Humana Press, 2013 9781627033664
Language:
English
Subjects:
Medicine
Keywords:
Peniskrebs
;
Peniskrebs
;
Aufsatzsammlung
DOI:
10.1007/978-1-62703-367-1
URL:
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