Format:
Online-Ressource (V, 110p. 13 illus., 10 illus. in color, digital)
ISBN:
9783540876311
,
1283369532
,
9781283369534
Series Statement:
Reviews of Physiology, Biochemistry and Pharmacology 161
Content:
This title includes: F. Schweda and A. Kurtz: ""Regulation of Renin Release by Local and Systemic Factors""; M. Krauss and V. Haucke: ""Shaping Membranes for Endocytosis; B.M. Jockusch and P.L. Graumann: ""The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells""; B. Colsoul, R. Vennekens and B. Nilius: ""Transient Receptor Potential (TRP) Cation Channels in Pancreatic ss cells
Content:
1 Basic Mechanisms of Insulin Secretion in Beta Cells2 Role of Ion Channels: The Classical View; 3 Expression of TRP Channels in Pancreatic b Cells; 4 Modulation of Insulin Release by TRP Channels; 4.1 TRP Canonicals; 4.2 TRPM2; 4.3 TRPM3; 4.4 TRPM4; 5 TRPM5 as a Modulator of Ca 2+ Oscillations; 6 Lessons Form Knock-Out Models: TRPM2 and TRPM5; 7 An Intestinal TRPM5 Connection: Incretins; 8 TRPM3: A Zinc Connection; 9 TRP Channels and a Possible Role in Diabetes Type II; 10 TRPM5 as a Drug Target; 11 A Critical View: From Mouse to Man; References
Content:
A Matter of Stretching and Squeezing: Mechanical Forces Sculpt the MembraneOutlook; References; The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells; 1 Actin Homologues Are Present in Pro- and Eukaryotes; 2 Actin Filament-Based Dynamics in Eukaryotic and Prokaryotic Cells; 3 Involvement of Eukaryotic Actins in Nuclear Functions; 4 Comparing Pro- and Eukaryotic Actins: Dissimilarities and Similarities; 5 Evolution of the Eukaryotic Cell; 6 The Pathway of the Actin Ancestor; 7 Conclusion; References; Transient Receptor Potential Cation Channels in Pancreatic b Cells
Content:
Blood pressureRegulation of renin release by salt load; References; Shaping Membranes for Endocytosis; Taking a Trip into the Cell; Clathrin-Mediated Endocytosis; Caveolae-Mediated Endocytosis; Clathrin- and Caveolin-Independent Endocytosis; Phagocytosis; Generating Membrane Curvature at the Plasma Membrane; Asymmetric Membrane Expansion: Dipping Fingers into the Sea; Stabilizing Curved Membrane Domains by Biological Basket Weaving; Curving Through BARs; Assisting Curvature Induction: Local Changes in Lipid Composition and Organization
Content:
Reviews of Physiology, Biochemistryand Pharmacology; Contents; Regulation of Renin Release by Local and Systemic Factors; Introduction; The Process of Renin secretion; Intracellular signaling pathways controlling renin release; Cyclic AMP; Cyclic GMP; Calcium; Electrophysiology of JG cells; Role of intercellular communication for renin secretion; Locally acting factors that regulate renin release; Atrial natriuretic peptide; Angiotensin II; Prostaglandins E 2 and I 2; Nitric oxide; The macula densa mechanism; Renal baroreceptor mechanism; Systemic factors controlling renin release
Note:
Includes bibliographical references
Additional Edition:
ISBN 9783540876281
Additional Edition:
Buchausg. u.d.T. ISBN 978-3-540-87628-1
Language:
English
DOI:
10.1007/978-3-540-87631-1
URL:
Volltext
(lizenzpflichtig)
Author information:
Offermanns, Stefan 1964-
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