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Prions : a challenge for science, medicine and public health system (2001)

Rabenau, Holger ; Cinatl, Jindrich ; Doerr, Hans Wilhelm 1945-

Basel : Karger

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UID:

b3kat_BV036069354

Format: 1 Online-Ressource (VIII, 164 Seiten) , Illustrationen, Diagramme

ISBN: 9783318006223

Series Statement: Contributions to microbiology Vol. 7

Content: In the past decades, the public has been forced to revise its perception of the apparent triumph of modern hygiene and medical microbiology over infectious diseases. Not only have older infections reemerged but new epidemics, like AIDS, have lead to public uncertainty. With the onset of the bovine spongiform encephalopathy epidemic in Great Britain, novel infectious agents came into the public spotlight, ones that do not cause classical inflammation but a slow and irreversible degeneration of the central nervous system. Sensational from a scientific point of view, these agents, called proteinaceous infectious organisms or prions, were shown to be self-replicating without nucleic acid sequences to encode genomic information.In this volume, leading scientists deal with the medical, scientific and public health questions that prion infections raise. Besides the 'prion or virus' discussion, the structures of prions and their molecular biological analysis as well as the questions of strain variations and species barrier are presented. The etiological, clinical and diagnostic aspects of transmissible spongiform encephalopathies are given special attention. The epidemiology of human and animal prion diseases, disease management and possibilities for inactivation of prions are discussed from a public health perspective. Directed at scientists, physicians and the public health sector, the monograph uses a multidisciplinary approach to present the latest findings on prion infection

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7124-1

Language: English

Subjects: Medicine

RVK:

YG 4517

Keywords: Spongiöse subakute Encephalopathie ; Prion ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung

DOI: 10.1159/isbn.978-3-318-00622-3

URL: Volltext

URL: Volltext (Deutschlandweit zugänglich)

URL: Inhaltsverzeichnis

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Author information: Doerr, Hans Wilhelm 1945-

Author information: Rabenau, Holger

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Prions : a challenge for science, medicine and the public health system (2004)

Rabenau, Holger ; Cinatl, Jindrich ; Doerr, Hans Wilhelm 1945-

Basel : Karger

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UID:

b3kat_BV036069355

Format: 1 Online-Ressource (XI, 221 Seiten) , Illustrationen, Diagramme

Edition: 2nd, revised and extended edition

ISBN: 9783318010329

Series Statement: Contributions to microbiology Vol. 11

Content: This second, completely revised and extended edition of 〈i〉Prions: A Challenge for Science, Medicine and the Public Health System〈/i〉 is a comprehensive, up-to-date review of prions and prion-associated diseases. Leading scientists discuss the structure, molecular biology and origin of prions as well as strain variations and species barriers. Human prion diseases, prion inactivation and risks to public health are considered in detail. The new edition provides an update on basic findings of the last three years since publication of the previous edition and emphasizes practical aspects of fighting human and animal prion diseases. In addition, chapters on regulatory aspects of BSE and CJD as well as on veterinary measures have been included.A valuable single source of information on what is currently known about prions, this book will be of interest to any scientist or clinician who wants to keep up with the latest developments in this fast-moving field

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7656-7

Language: English

Subjects: Medicine

RVK:

YG 4500

RVK:

YG 4517

Keywords: Prion ; Spongiöse subakute Encephalopathie ; Jakob-Creutzfeldt-Syndrom ; Prionkrankheit ; Aufsatzsammlung

DOI: 10.1159/isbn.978-3-318-01032-9

URL: Volltext

URL: Volltext (Deutschlandweit zugänglich)

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Author information: Doerr, Hans Wilhelm 1945-

Author information: Rabenau, Holger

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New aspects of CMV-related immunopathology (2003)

Prösch, Susanna 1955- ; Cinatl, Jindrich ; Scholz, Martin 1960-

Basel : Karger

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UID:

b3kat_BV036069276

Format: 1 Online-Ressource (X, 212 Seiten) , Illustrationen, Diagramme

ISBN: 9783318010060

Series Statement: Monographs in virology Vol. 24

Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell.This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed.The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs

Note: 4th Symposium, Berlin, September 2002

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7618-5

Language: English

Subjects: Medicine

RVK:

YD 7405

Keywords: Cytomegalie ; Infektion ; Immunpathologie ; Konferenzschrift

DOI: 10.1159/isbn.978-3-318-01006-0

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CMV-related immunopathology (1998)

Scholz, Martin 1960- ; Rabenau, Holger ; Doerr, Hans Wilhelm 1945- ; [et al.]

Basel : Karger

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UID:

b3kat_BV036069070

Format: 1 Online-Ressource (XII, 308 Seiten) , Illustrationen, Diagramme

ISBN: 9783318002621

Series Statement: Monographs in virology Vol. 21

Content: Cytomegalovirus (CMV) infection can cause severe diseases with significant morbidity and mortality in immunocompromised patients such as bone marrow or solid-organ transplant recipients, and AIDS patients. Major manifestations include transplant rejection, hepatitis, pneumonitis, encephalitis and retinitis. There is growing evidence that in certain cases CMV disease is closely linked to aberrant immune responses occurring locally within the respective tissues.This book provides important new insights into CMV-related immunopathology, discusses current methods of CMV diagnosis and anti-CMV therapy, and proposes novel antiviral treatment strategies. It contains contributions by leading scientists and clinicians in the field of CMV, who participated in the 'First International Round Table Consensus Meeting', held in Frankfurt, Germany, in August 1997. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working on herpesvirus biology and the development of antiviral drugs

Note: 1st International Consensus Round Table Meeting, Frankfurt, August 1997 ; expert reviews on current and future anti-CMV treatment strategies

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6602-5

Language: English

Subjects: Medicine

RVK:

XD 7400

RVK:

YD 7405

Keywords: Cytomegalie-Virus ; Infektion ; Immunpathologie ; Cytomegalie ; Konferenzschrift

DOI: 10.1159/isbn.978-3-318-00262-1

URL: Volltext

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Author information: Doerr, Hans Wilhelm 1945-

Author information: Rabenau, Holger

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Article

Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3 (2009)

Michaelis, Martin ; Rothweiler, Florian ; Klassert, Denise ; [et al.]

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UID:

gbv_657925934

Format: 6

ISSN: 0008-5472

In: Cancer research, Birmingham, Ala. [u.a.] : AACR, 1941, 69(2009), 2, Seite 416-421, 0008-5472

In: volume:69

In: year:2009

In: number:2

In: pages:416-421

In: extent:6

Language: Undetermined

Author information: Fehse, Boris

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The clinical value of neutrophil extracellular traps (2009)

Lögters, Tim ; Margraf, Stefan ; Altrichter, Jens ; [et al.]

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UID:

gbv_614471192

Format: graph. Darst.

ISSN: 0300-8584

In: Medical microbiology and immunology, Berlin : Springer, 1972, 198(2009), 4, Seite 211-219, 0300-8584

In: volume:198

In: year:2009

In: number:4

In: pages:211-219

Language: English

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