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Engineering in life sciences (2001)

Weinheim : Wiley-VCH ; 1.2001 -

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UID:

gbv_341913782

Format: Online-Ressource

ISSN: 1618-2863

Note: Gesehen am 10.11.2022

Additional Edition: ISSN 1618-0240

Additional Edition: Erscheint auch als Druck-Ausgabe Engineering in life sciences Weinheim : Wiley-Blackwell, 2001 ISSN 1618-0240

Former: 2003 darin aufgeg Acta biotechnologica

Language: English

Keywords: Zeitschrift

DOI: 10.1002/(ISSN)1618-2863

URL: https://doi.org/10.1002/(ISSN)1618-2863

URL: kostenfrei

URL: https://ezb.ur.de/?2071199-2

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Batch-to-batch variability of two human designer cell lines : AGE1.HN and AGE1.HN.AAT ; carried out by different laboratories under defined culture conditions using a mathematical model (2013)

Freund, Susann ; Rath, Alexander 1978- ; Barradas, Oscar Platas ; [et al.]

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UID:

gbv_772177848

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 13(2013), 6, Seite 580-592, 1618-2863

In: volume:13

In: year:2013

In: number:6

In: pages:580-592

Language: English

DOI: 10.1002/elsc.201200111

URL: Volltext

Author information: Zeng, An-Ping 1963-

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Cultivation of Chlorella vulgaris in microfluid segments and microtoxicological determination of their sensitivity against CuCl2 in the nanoliter range (2011)

Brauer, Dana 1976- ; Cao-Riehmer, Jialan 1979- ; Funfak, Anette 1979- ; [et al.]

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UID:

gbv_68293366X

ISSN: 1618-2863

Content: The cultivation of the monocellular green alga Chlorella vulgaris was implemented into microfluid segments to demonstrate the possibility of an automated screening of toxic effects of the common algaecide CuCl2. Therefore, the nutritional as well as light and carbon dioxide requirements of the algae had to be adapted to the microfluidic device. Generally, sequences of about 350 fluid segments with single volumes of about 500 nL were applied for the dose-response experiments. The growth of algae cultures inside microfluidic segments was noninvasively measured by microflow through techniques using two different optical channels. A multi-endpoint detection was realized by the photometric characterization of cell density by transmission measurements and the measurement of density of autofluorescent cells. The different methods revealed comparable half maximal effective concentrations (EC50) in the range between 34.6 and 39.9 mg/mL for the toxicity of CuCl2 to the green algae C. vulgaris. By reference experiments in microtiter plates lower EC50 were achieved presumably caused by increased alkalinity of the growth medium due to higher photosynthesis. The results show that the microsegmented flow technique is well suited for the automated determination of dose/response functions for microorganisms like C. vulgaris and for the application of multi-endpoint procedures at the nanoliter scale.

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 11(2011), 6, Seite 580-587, 1618-2863

In: volume:11

In: year:2011

In: number:6

In: pages:580-587

Language: English

URL: Volltext

Author information: Brauer, Dana 1976-

Author information: Funfak, Anette 1979-

Author information: Köhler, Michael 1956-

Author information: Cao-Riehmer, Jialan 1979-

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Editorial: microtechnology for life science applications (2011)

Köhler, Michael 1956-

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UID:

gbv_682930253

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 11(2011), 2, Seite 116-117, 1618-2863

In: volume:11

In: year:2011

In: number:2

In: pages:116-117

Language: English

URL: Volltext

Author information: Köhler, Michael 1956-

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Evaluation of criteria for bioreactor comparison and operation standardization for mammalian cell culture (2012)

Platas Barradas, Oscar 1980- ; Jandt, Uwe ; Phan, Linh Da Minh ; [et al.]

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UID:

gbv_733882609

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 12(2012), 5, Seite 518-528, 1618-2863

In: volume:12

In: year:2012

In: number:5

In: pages:518-528

Language: English

DOI: 10.1002/elsc.201100163

URL: Volltext

Author information: Zeng, An-Ping 1963-

Author information: Pörtner, Ralf 1958-

Author information: Platas Barradas, Oscar 1980-

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Influence of the production system on the surface properties of influenza A virus particles (2017)

Hämmerlein, Frank [VerfasserIn] ; Pieler, Michael M. [VerfasserIn] ; Hennig, René [VerfasserIn] ; [et al.]

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UID:

gbv_1002740088

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 17(2017), 10, Seite 1071-1077, 1618-2863

In: volume:17

In: year:2017

In: number:10

In: pages:1071-1077

Language: English

DOI: 10.1002/elsc.201700058

URL: Volltext

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Integration of 3-D cell cultures in fluidic microsystems for biological screenings (2011)

Witte, Hartmut 1961- ; Stubenrauch, Mike ; Fröber, Ulrike 1979- ; [et al.]

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UID:

gbv_657377597

ISSN: 1618-2863

Content: A life support system for the cultivation of adherent 2-D and scaffold-based 3-D cell cultures in a microfluidic device, a Bio-Micro-Electro-Mechanical System (BioMEMS) is presented. The miniaturization level and system set-up allow incubator-independent operation modes and long-term experiments with real-time microscope observation. A dedicated seeding procedure for adherent cells into the microstructures is one key issue of the BioMEMS developed. Several seeding methods for the cells were evaluated. Biocompatibility of all materials, surfaces and methods could be demonstrated. First experiments with several cell types show the feasibility of the approach employing standard laboratory protocols. At present, the modular design and set-up offer a broad application spectrum as well as its future extension to e.g. culti.

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 11(2011), 2, Seite 140-147, 1618-2863

In: volume:11

In: year:2011

In: number:2

In: pages:140-147

Language: English

URL: Volltext

Author information: Fröber, Ulrike 1979-

Author information: Hoffmann, Martin 1966-

Author information: Witte, Hartmut 1961-

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Microbioreactor design for 3-D cell cultivation to create a pharmacological screening system (2011)

Fernekorn, Uta 1975- ; Hampl, Jörg ; Weise, Frank ; [et al.]

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UID:

gbv_682932442

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 11(2011), 2, Seite 133-139, 1618-2863

In: volume:11

In: year:2011

In: number:2

In: pages:133-139

Language: English

URL: Volltext

Author information: Hildmann, Christian 1972-

Author information: Augspurger, Caroline

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Mimicking the biological world: methods for the 3D structuring of artificial cellular environments (2013)

Schober, Andreas 1961- ; Fernekorn, Uta 1975- ; Singh, Sukhdeep 1980- ; [et al.]

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UID:

gbv_766438090

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 13(2013), 4, Seite 352-367, 1618-2863

In: volume:13

In: year:2013

In: number:4

In: pages:352-367

Language: English

URL: Volltext

Author information: Singh, Sukhdeep 1980-

Author information: Williamson, Adam 1980-

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Modeling of PAH Elimination by Adiabatic Steam Stripping and Intraparticle Desorption (2003)

Frishfelds, B. [VerfasserIn] ; Niemeyer, Bernd [VerfasserIn] 1973- ; Höhne, Joachim [VerfasserIn] ; [et al.]

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UID:

gbv_1029138184

ISSN: 1618-2863

In: Engineering in life sciences, Weinheim : Wiley-VCH, 2001, 3(2003), 5, Seite 226-232, 1618-2863

In: volume:3

In: year:2003

In: number:5

In: pages:226-232

Language: English

DOI: 10.1002/elsc.200390032

URL: Volltext

Author information: Niemeyer, Bernd 1973-

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Kooperativer Bibliotheksverbund

Berlin Brandenburg