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Visit-to-visit blood pressure variability and the risk of stroke in the Netherlands: A population-based cohort study

Fig 1

Schematic presentation of the analyses with and without a lag period.

(A) Analyses without lag periods, in which blood pressure (BP) variability is measured over 2 visits with immediate follow-up for stroke incidence thereafter. Blood pressure variability is then updated when the participant visits the research center again. (B) Analyses with lag periods. After blood pressure variability measurement, a lag period of 3, 6, or 9 years is incorporated before follow-up for incident stroke to account for reversed causation.

Fig 1

doi: https://doi.org/10.1371/journal.pmed.1003942.g001