Oncolytic Effects of a Novel Influenza A Virus Expressing Interleukin-15 from the NS Reading Frame
Figure 1
Influence of influenza A virus infection on melanoma cell viability.
Cells were infected at a MOI of 1 with IVR-116 (expressing WT NS1), delNS1 or delNS1-IL-15. MTT-assay was performed after 24, 48, and 72 hours post infection (left panel) or cells were infected at MOIs ranging from 1 to 0.01 and MTT-Assay was performed 72 hours post infection (right panel). All data represent mean ± SD of three independent experiments. *significantly different compared to non-infected control (mock), P<0.05.