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Nuclear Overhauser Enhancement Mediated Chemical Exchange Saturation Transfer Imaging at 7 Tesla in Glioblastoma Patients

Figure 1

Peritumoral hyperintensity on NOE mediated CEST compared to standard MRI.

Left frontal glioblastoma in a 59 year old man at 3 Tesla, CE-T1 (A) and T2-weighted images (B). On the selected slice the CEST contrast at 7 Tesla, based on MTRasym (C), displays peritumoral hyperintensities at equal extent compared to the edema on T2-weighted images. In contrast to T2-weighted images, the CEST peritumoral hyperintensity displays an irregular border and subareas of different signal intensity.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0104181.g001