Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins
Figure 2
Analysis of CD cleavage characteristics in denatured OVA.
A, Sequence logos of the CD cleavage sites in native OVA (left) and denatured OVA (right). B, The sensitivity of denatured OVA to CD cleavage was examined via SDS-PAGE, in which the denatured protein was incubated with/without CD and pepstatin A for 3 h. C, The median T-HSNs, C-HSNs and U-HSNs in denatured OVA are depicted using box plots. D, Comparison of the HSN distributions between the cleaved and undetected peptides from denatured OVA.