Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia
Fig 2
(A—F) Transnasal infection of mice with S. aureus (5 x 107 CFU/ mouse) resulted in non-expansive (A), suppurative (B, C) to necrotizing (D) bronchopneumonia with infiltration of neutrophils and lymphocytes into perivascular spaces (E) and protein-rich alveolar edema (F, asterisk). (A–F) Representative images are shown. Bars (A), 1 mm; (C, D, F), 20 μm; (B, E), 50 μm.