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Phage-Antibiotic Synergy (PAS): β-Lactam and Quinolone Antibiotics Stimulate Virulent Phage Growth

Figure 3

Increase in phage titer in the presence of the cephalosporin cefotaxime (CTX).

E. coli strain MFP was infected with phage ΦMFP in Luria liquid medium supplemented at the time of infection with 20 ng/mL of cefotaxime, or left untreated. The multiplicity of infection was ∼5. Chloroform was added at various times after infection to lyse the infected cells.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0000799.g003